Granted Patent
Utility
PCT National Stage
US 12,655,403
· Confirmation No. 5070
SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING
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⬇ PDF
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Code | Description | Pages | ||
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| 2026-06-24 | PET.PTA |
Patent Term Adjustment Petition | 15 | View | |
| 2026-06-24 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-06-24 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-06-16 | EGRANT.PDF |
Digitally signed official patent eGrant document | — | View | |
| 2026-06-16 | EGRANT.NTF |
eGrant day-of Notification | 2 | View | |
| 2026-06-03 | ISSUE.NTF |
Issue Notification | 2 | View | |
| 2026-05-28 | PET.OP |
Petition for review by the Office of Petitions | 4 | View | |
| 2026-05-28 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-05-19 | SES.LOSS.PC |
Notification of loss of entitlement to small entity status via PC | 1 | View | |
| 2026-05-08 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2026-05-08 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-05-08 | IFEE |
Issue Fee Payment (PTO-85B) | 2 | View | |
| 2026-03-06 | N271 |
Response to Amendment under Rule 312 | 2 | View | |
| 2026-02-20 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2026-02-20 | A.NA |
Amendment after Notice of Allowance (Rule 312) | — | View | |
| 2026-02-20 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2026-02-20 | DRW |
Drawings-only black and white line drawings | 3 | View | |
| 2026-02-20 | A.NA |
Amendment after Notice of Allowance (Rule 312) | 1 | View | |
| 2026-02-20 | SPEC |
Specification | 1 | View | |
| 2026-02-20 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2026-02-20 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2026-02-19 | M327 |
Miscellaneous Communication to Applicant - No Action Count | 4 | View | |
| 2026-02-11 | NOA |
Notice of Allowance and Fees Due (PTOL-85) | 9 | View | |
| 2026-02-11 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2026-02-11 | IIFW |
Issue Information including classification, examiner, name, claim, renumbering, etc. | 3 | View | |
| 2026-02-11 | SRNT |
Examiner's search strategy and results | 10 | View | |
| 2026-02-11 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2025-11-19 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | — | View | |
| 2025-11-19 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2025-11-19 | CLM |
Claims | 9 | View | |
| 2025-11-19 | REM |
Applicant Arguments/Remarks Made in an Amendment | 2 | View | |
| 2025-11-19 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-11-19 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-08-19 | CTNF |
Non-Final Rejection | 12 | View | |
| 2025-08-19 | SRFW |
Search information including classification, databases and other search related notes | 2 | View | |
| 2025-08-19 | SRNT |
Examiner's search strategy and results | 3 | View | |
| 2025-08-19 | SRNT |
Examiner's search strategy and results | 4 | View | |
| 2025-08-19 | SRNT |
Examiner's search strategy and results | 8 | View | |
| 2025-07-18 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | — | View | |
| 2025-07-18 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | 1 | View | |
| 2025-07-18 | CLM |
Claims | 9 | View | |
| 2025-07-18 | REM |
Applicant Arguments/Remarks Made in an Amendment | 7 | View | |
| 2025-07-18 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-07-18 | 136A |
Authorization for Extension of Time all replies | 2 | View | |
| 2025-07-18 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2025-07-18 | RCEX |
Request for Continued Examination (RCE) | 3 | View | |
| 2025-07-18 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-03-19 | CTFR |
Final Rejection | 58 | View | |
| 2025-03-19 | 892 |
List of references cited by examiner | 1 | View | |
| 2025-03-19 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2025-03-19 | SRNT |
Examiner's search strategy and results | 3 | View | |
| 2025-03-19 | SRNT |
Examiner's search strategy and results | 9 | View | |
| 2024-12-18 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-12-18 | REM |
Applicant Arguments/Remarks Made in an Amendment | 3 | View | |
| 2024-12-18 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2024-12-18 | CLM |
Claims | 2 | View | |
| 2024-12-18 | CLM |
Claims | 9 | View | |
| 2024-12-18 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-10-18 | CTRS |
Requirement for Restriction/Election | 8 | View | |
| 2024-10-18 | 892 |
List of references cited by examiner | 1 | View | |
| 2024-08-12 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2024-08-12 | XT/ |
Extension of Time | 2 | View | |
| 2024-08-12 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2024-08-12 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2024-08-12 | CLM |
Claims | 10 | View | |
| 2024-08-12 | REM |
Applicant Arguments/Remarks Made in an Amendment | 5 | View | |
| 2024-08-12 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2024-04-12 | CTNF |
Non-Final Rejection | 48 | View | |
| 2024-04-12 | 892 |
List of references cited by examiner | 1 | View | |
| 2024-04-12 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2024-04-12 | SRNT |
Examiner's search strategy and results | 2 | View | |
| 2024-03-22 | C.AD.PC |
Change of Address via Patent Center | 1 | View | |
| 2024-03-22 | MFEE.C.AD.PC |
Change of Address via Patent Center | 1 | View | |
| 2024-03-14 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2024-03-14 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 24 | View | |
| 2023-12-29 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-12-29 | REM |
Applicant Arguments/Remarks Made in an Amendment | 435 | View | |
| 2023-12-29 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-12-29 | RCEX |
Request for Continued Examination (RCE) | 3 | View | |
| 2023-12-29 | XT/ |
Extension of Time | 2 | View | |
| 2023-12-29 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2023-12-29 | SPEC |
Specification | 435 | View | |
| 2023-12-29 | AMSB |
Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE) | 1 | View | |
| 2023-12-29 | SPEC |
Specification | 2 | View | |
| 2023-12-29 | CLM |
Claims | 10 | View | |
| 2023-12-29 | REM |
Applicant Arguments/Remarks Made in an Amendment | 14 | View | |
| 2023-12-29 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2023-12-29 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-08-29 | CTFR |
Final Rejection | 51 | View | |
| 2023-08-29 | 892 |
List of references cited by examiner | 1 | View | |
| 2023-08-29 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2023-08-29 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2023-06-08 | CRFD |
Sequence Listing in Computer Readable Format is Defective | — | View | |
| 2023-06-08 | CRFD |
Sequence Listing in Computer Readable Format is Defective | 25 | View | |
| 2023-06-07 | REM |
Applicant Arguments/Remarks Made in an Amendment | 439 | View | |
| 2023-06-07 | SPEC |
Specification | 435 | View | |
| 2023-06-07 | DRW.NONBW |
Drawings-other than black and white line drawings | 75 | View | |
| 2023-06-07 | DRW.NONBW |
Drawings-other than black and white line drawings | 60 | View | |
| 2023-06-07 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-06-07 | XT/ |
Extension of Time | 2 | View | |
| 2023-06-07 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2023-06-07 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2023-06-07 | A... |
Amendment/Request for Reconsideration-After Non-Final Rejection | 1 | View | |
| 2023-06-07 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2023-06-07 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2023-06-07 | SPEC |
Specification | 1 | View | |
| 2023-06-07 | CLM |
Claims | 10 | View | |
| 2023-06-07 | REM |
Applicant Arguments/Remarks Made in an Amendment | 10 | View | |
| 2023-06-07 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2023-06-07 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2023-06-07 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2023-06-07 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2023-06-07 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2023-02-07 | CTNF |
Non-Final Rejection | 60 | View | |
| 2023-02-07 | 892 |
List of references cited by examiner | 1 | View | |
| 2023-02-07 | SRFW |
Search information including classification, databases and other search related notes | 1 | View | |
| 2023-02-07 | 1449 |
List of References cited by applicant and considered by examiner | 5 | View | |
| 2023-02-07 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2023-02-07 | 1449 |
List of References cited by applicant and considered by examiner | 4 | View | |
| 2023-02-07 | BIB |
Bibliographic Data Sheet | 2 | View | |
| 2023-02-07 | SRNT |
Examiner's search strategy and results | 1 | View | |
| 2023-02-07 | 1449 |
List of References cited by applicant and considered by examiner | 9 | View | |
| 2022-11-07 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2022-11-07 | ELC. |
Response to Election / Restriction Filed | 1 | View | |
| 2022-11-07 | CLM |
Claims | 7 | View | |
| 2022-11-07 | REM |
Applicant Arguments/Remarks Made in an Amendment | 4 | View | |
| 2022-09-07 | CTRS |
Requirement for Restriction/Election | 10 | View | |
| 2021-12-22 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-12-22 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-07-30 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 4 | View | |
| 2021-07-30 | FOR |
Foreign Reference | 377 | View | |
| 2021-07-30 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2021-07-30 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2021-07-30 | FOR |
Foreign Reference | 463 | View | |
| 2021-07-30 | FOR |
Foreign Reference | 616 | View | |
| 2021-06-04 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-06-04 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-05-06 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2021-04-13 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-04-13 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-04-12 | N570 |
Communication - Re: Power of Attorney (PTOL-308) | 1 | View | |
| 2021-04-09 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-04-09 | OATH |
Oath or Declaration filed | 2 | View | |
| 2021-04-09 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-04-08 | PA.. |
Power of Attorney | 2 | View | |
| 2021-04-08 | PA.. |
Power of Attorney | 2 | View | |
| 2021-04-08 | PA.. |
Power of Attorney | 2 | View | |
| 2021-04-08 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-04-02 | M903 |
Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed | 2 | View | |
| 2021-04-02 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2021-04-02 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2021-04-02 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2021-03-26 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2021-03-26 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2021-03-26 | PEFR |
Applicant Response to Pre-Exam Formalities Notice | 1 | View | |
| 2021-03-26 | CLM |
Claims | 8 | View | |
| 2021-03-26 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View | |
| 2021-01-26 | WCLM |
Claims Worksheet (PTO-2022) | 1 | View | |
| 2021-01-26 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2021-01-26 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2021-01-26 | 371.FEE.M923 |
371 (National Stage) Supplemental Fees Missing - Form M923 | 2 | View | |
| 2020-10-20 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 19 | View | |
| 2020-05-01 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 9 | View | |
| 2020-05-01 | REF.OTHER |
Other reference-Patent/Application/Search Documents | 3 | View | |
| 2020-05-01 | N417 |
Electronic Filing System Acknowledgment Receipt | 16 | View | |
| 2020-05-01 | REF.OTHER |
Other reference-Patent/Application/Search Documents | 16 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 88 | View | |
| 2020-05-01 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2020-05-01 | TRAN.LET |
Transmittal Letter | 2 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 72 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 300 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 403 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 822 | View | |
| 2020-05-01 | FOR |
Foreign Reference | 582 | View | |
| 2020-04-15 | DRW |
Drawings-only black and white line drawings | 135 | View | |
| 2020-04-15 | SPEC |
Specification | 433 | View | |
| 2020-04-15 | CLM |
Claims | 7 | View | |
| 2020-04-15 | ABST |
Abstract | 2 | View | |
| 2020-04-15 | 371P |
Documents submitted with 371 (National Stage) Applications | 11 | View | |
| 2020-04-15 | P.306 |
PCT/IB/306 - Notification of the Recording of a Change | 1 | View | |
| 2020-04-15 | FRPR |
Certified Copy of Foreign Priority Application | 612 | View | |
| 2020-04-15 | P.N.101.CONV |
PCT/RO/101 - Request form for new International Application - Conventional | 7 | View | |
| 2020-04-15 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View | |
| 2020-04-15 | TRNA |
Transmittal of New Application | 4 | View | |
| 2020-04-15 | ADS |
Application Data Sheet | 11 | View | |
| 2020-04-15 | 371P |
Documents submitted with 371 (National Stage) Applications | 7 | View | |
| 2020-04-15 | 371P |
Documents submitted with 371 (National Stage) Applications | 2 | View | |
| 2020-04-15 | 371P |
Documents submitted with 371 (National Stage) Applications | 1 | View | |
| 2020-04-15 | WFEE |
Fee Worksheet (SB06) | 2 | View | |
| 2020-04-15 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2020-04-15 | A.PE |
Preliminary Amendment | 1 | View | |
| 2020-04-15 | SPEC |
Specification | 1 | View | |
| 2020-04-15 | REM |
Applicant Arguments/Remarks Made in an Amendment | 1 | View |
Inventors
Feng Zhang
Cambridge, MA
Jonathan Gootenberg
Cambridge, MA
David Benjamin Turitz Cox
Cambridge, MA
Omar Abudayyeh
Cambridge, MA
Ian Slaymaker
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
800/8
C12N9/22
C12N15/113
C12N2310/20
A61P43/00
A61K9/50
C07K2319/85
C12N9/78
C12N15/11
C12N15/111
C12N15/85
C12N2320/32
C12N2320/34
C12N2800/80
C12Y305/04001
C12Y305/04004
C12Y305/04005
Prosecution
- Examiner
- NOAKES, SUZANNE MARIE
- Art Unit
- 1656
- Customer No.
- 198696
- Docket No.
- BROD-2365US
- Confirmation No.
- 5070
Publication
- Pub. No.
- US20210130800A1
- Pub. Date
- 2021-05-06
Patent Term Adjustment
-128days
Parent
PCT
is a National Stage Entry of
→
PCT/US2018/057177
Filed 2018-10-23
· Patented Case
Parent
Claims priority from a provisional application
→
App. 62/576,061
Filed 2017-10-23
· Provisional Application Expired
Child
is a Division of
→
App. 19/677,353
Filed 2026-05-14
· Application Undergoing Preexam Processing
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
LICENSE
Recorded 2025-03-21
from
ZHANG, FENG
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2020-11-03
from
ABUDAYYEH, OMAR
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2020-11-03
from
GOOTENBERG, JONATHAN
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2020-11-03
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2020-11-03
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Quick Facts
- Patent No.
- US 12,655,403
- App. No.
- 16/756,139
- Filed
- 2020-04-15
- Granted
- 2026-06-16
- Pub. No.
- US20210130800A1
- Examiner
- NOAKES, SUZANNE MARIE
- Art Unit
- 1656
- PTA
- -128 days
External Links