Extended wear-time dressing
As an example, in some embodiments is a dressing that may comprise a manifold, a bioresorbable component, and a degradation-modulating component. The degradation-modulating component may cover two or more surfaces of the bioresorbable component. The degradation-modulating component may be further configured to modulate degradation of the bioresorbable component.
1. A negative pressure system for providing negative pressure therapy to a tissue site, the system comprising:
a manifold;
a bioresorbable component having a first surface and a second surface opposite the first surface;
a degradation-modulating component covering the first surface and the second surface of the bioresorbable component and configured to modulate degradation of the bioresorbable component, the degradation-modulating component comprising a polymer having a monomeric unit, the monomeric unit comprising vinyl pyrrolidone, vinyl alcohol, ethylene oxide, propylene oxide, ethylene glycol, acrylic acid, a salt of acrylic acid, an ester of acrylic acid, acrylamido methylpropane sulphonic acid, a salt of acrylamido methylpropane sulphonic acid, an ester of acrylamido methylpropane sulphonic acid, cellulose derivatives, copolymers thereof, blends or mixtures thereof, or combinations thereof,
a cover configured to be placed over the manifold, the bioresorbable component, and the degradation-modulating component; and
a negative-pressure source configured to be fluidly coupled to the manifold.
2. The negative pressure system of claim 1 , wherein the manifold comprises a hydrophobic, open-cell foam.
3. The negative pressure system of claim 1 , wherein the manifold is formed from polyurethane.
4. The negative pressure system of claim 1 , wherein the bioresorbable component exhibits protease-modulating activity.
5. The negative pressure system of claim 1 , wherein of the bioresorbable component comprises collagen and oxidized, regenerated cellulose.