IP Library Granted Patent US 12,558,049
Granted Patent B2
US 12,558,049 · App. 18/478,551 · Granted Feb 24, 2026

Method for generating a contrast-enhanced mammogram recording

Inventor: Mathias Hoernig (Moehrendorf, DE)
Assignee: SIEMENS HEALTHINEERS AG
A61B6/502A61B6/025A61B10/0041A61B10/0233G06T5/50G06T5/92G06T11/60A61B6/12A61B6/481A61B6/482G06T2207/10081G06T2207/20224G06T2207/30068G06T2210/41
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Quick Facts
Patent No.
US 12,558,049
App. No.
18/478,551
Granted
Feb 24, 2026
Kind
B2
Abstract

A method for generating a plurality of contrast-enhanced mammograms of an examination region is described. In the method a plurality of at least two different angular positions is defined for a contrast-enhanced tomosynthesis projection recording of an examination region. At least two low-energy tomosynthesis projection recordings of the examination region are subsequently generated, starting from the at least two different angular positions, in the presence of a contrast agent. Furthermore, at least two high-energy tomosynthesis projection recordings of the examination region are generated, starting from the at least two different angular positions, in the presence of a contrast agent. Finally, at least two contrast-enhanced mammograms are generated by subtracting a respective low-energy tomosynthesis projection recording from a respective high-energy tomosynthesis projection recording for a respective angular position. In addition, a mammography system is described.

Claims (60)

1 . A method for generating a plurality of contrast-enhanced mammograms of an examination region, the method comprising:

defining a plurality of at least two different angular positions for a tomosynthesis projection recording;

generating at least two low-energy tomosynthesis projection recordings of the examination region from the at least two different angular positions in a presence of a contrast agent;

generating at least two high-energy tomosynthesis projection recordings of the examination region from the at least two different angular positions in the presence of the contrast agent; and

generating at least two contrast-enhanced mammograms by subtracting the respective low-energy tomosynthesis projection recording from the respective high-energy tomosynthesis projection recording for a respective angular position.

2 . The method of claim 1 , wherein

the plurality of at least two different angular positions comprises at least three different angular positions,

the at least three different angular positions are divided into first angular positions and second angular positions, wherein the second angular positions comprise at least two different angular positions,

the low-energy tomosynthesis projection recordings are generated s sting-from the first angular positions and the second angular positions,

the high-energy tomosynthesis projection recordings are generated from the second angular positions, and

a recombined tomosynthesis representation is generated based on the low-energy tomosynthesis projection recordings.

3 . The method of claim 2 , wherein

the generating the low-energy tomosynthesis projection recordings at the first angular positions includes,

using a first current-time product for actuating an X-ray source for generating the low-energy tomosynthesis projection recordings, and

the generating the low-energy synthesis projection recordings at the second angular positions includes using a second current-time product for actuating the X-ray source for generating the low-energy tomosynthesis projection recordings; and

the generating the high-energy tomosynthesis projection recordings includes, using the second current-time product for actuating the X-ray source for generating the high-energy tomosynthesis projection recordings.

4 . The method of claim 3 , wherein a value of the second current-time product is higher than a value of the first current-time product.

5 . The method of claim 3 , wherein the second angular positions comprise the angular position 0°.

6 . The method of claim 5 , wherein the first angular positions comprise at least three angular positions.

7 . The method of claim 6 , wherein the second angular positions are defined as a function of at least one of

the angular positions of previous recordings, or

a z-position of a suspected lesion.

8 . The method of claim 7 , further comprising:

generating at least two mid-energy tomosynthesis projection recordings of the examination region from the at least two different angular positions, in a presence of the contrast agent for at least one mid X-ray energy, the mid X-ray energy being between the low energy and the high energy; and

generating material-specific mammograms based on the two mid-energy tomosynthesis projection recordings.

9 . The method of claim 2 , wherein the second angular positions comprise at least the angular positions of −15° and +15°.

10 . The method of claim 2 , wherein the second angular positions comprise the angular position 0°.

11 . The method of claim 2 , wherein the first angular positions comprise at least three angular positions.

12 . The method of claim 11 , wherein the first angular positions comprise between nine and 22 angular positions.

13 . The method of claim 2 , wherein the second angular positions are defined as a function of at least one of

the angular positions of previous recordings, or

a z-position of a suspected lesion.

14 . The method of claim 2 , further comprising:

ascertaining a position of a biopsy needle in at least one of the following image representations,

in contrast-enhanced mammograms of the at least two contrast-enhanced mammograms, which are based on the tomosynthesis projection recordings of the second angular positions,

in the low-energy tomosynthesis projection recordings of the second angular positions, or

in the recombined tomosynthesis representations of the low-energy tomosynthesis projection recordings of at least one of the first angular positions or second angular positions.

15 . The method of claim 1 , further comprising:

generating at least two mid-energy tomosynthesis projection recordings of the examination region from the at least two different angular positions, in a presence of the contrast agent for at least one mid X-ray energy, the mid X-ray energy being between the low energy and the high energy; and

generating material-specific mammograms based on the two mid-energy tomosynthesis projection recordings.

16 . The method of claim 1 , further comprising:

ascertaining one of the following image representations-based on the generated tomosynthesis projection recordings,

a digital recombined low-energy breast tomosynthesis representation,

a synthetic low-energy 2D mammogram,

a contrast-enhanced recombined tomosynthesis representation,

a mammogram processed from a tomosynthesis projection recording for a second angular position,

a contrast-enhanced mammogram for a second angular position, the contrast-enhanced mammogram for the second angular position being one of the at least two contrast-enhanced mammograms, or

a projection recording of a low-energy tomosynthesis projection recording overlaid with an image representation of a contrast-enhanced mammogram; and

supplying the ascertained image representation to a user.

17 . A mammography system including a mammography processor, the mammography processor configured to cause the mammography system to:

define a plurality of at least two different angular positions for a contrast-enhanced tomosynthesis projection recording of an examination region,

generate at least two low-energy tomosynthesis projection recordings of the examination region, from the at least two different angular positions, in a presence of a contrast agent,

generate at least two high-energy tomosynthesis projection recordings of the examination region, from the at least two different angular positions, in the presence of a contrast agent; and

generate at least two contrast-enhanced mammograms by subtracting the respective low-energy tomosynthesis projection recording from the respective high-energy tomosynthesis projection recording for a respective angular position.

18 . A mammography system, comprising:

an X-ray source configured to emit X-ray radiation;

an X-ray detector unit configured to detect the emitted X-ray radiation; and

the mammography processor of claim 17 , the mammography processor configured to actuate the X-ray source and evaluate the X-ray radiation detected by the X-ray detector unit.

19 . A non-transitory computer program product including program segments, which when executed by a computing unit, cause the computing unit to perform the method of claim 1 .

20 . A non-transitory computer-readable medium including program segments, which when executed by a computing unit, cause the computing unit to perform the method of claim 1 .

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2025
From: HÖRNIG, MATHIAS
To: SIEMENS HEALTHINEERS AG
Reel/Frame 072860/0257 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066267/0346 →
Priority Claims (1)
DE 10 2022 210 408.0 · Sep 30, 2022 · national
Continuity (1)
Related Publication 20240108298A1 · Apr 4, 2024
References Cited (2)
US 20120134464A1 · Hoernig · 2012 [cited by examiner]
US 20150327826A1 · Smith · 2015 [cited by examiner]