Patent Assignment
Reel/Frame 051722/0304
Release of Security Interest
Recorded: 2020-01-28
Pages: 10
Assignor
ORBIMED ROYALTY OPPORTUNITIES II, LP
Executed: 2020-01-23
Assignees
PHARMING GROUP N.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
PHARMING TECHNOLOGIES B.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
PHARMING INTELLECTUAL PROPERTY B.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
BROEKMAN INSTITUUT B.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
PHARMING B.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
PHARMING AMERICAS B.V.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
PHARMING HEALTHCARE, INC.
DARWINWEG 24, 2333 CR, LEIDEN, NETHERLANDS
Covered Properties
(65)
Expression of Exogenous Recombinant Proteins from the Milk of Trans- Genic Mammals
Patent:
4,873,316 →
Application:
07/065,994 →
Multiplying Bovine Embryos
Patent:
4,994,384 →
Application:
07/113,791 →
Dna Sequences to Target Proteins to the Mammary Gland for Efficient Secretion
Patent:
5,304,489 →
Application:
07/602,066 →
Peptide Production
Patent:
5,366,894 →
Application:
07/796,439 →
Peptide Production
Patent:
5,322,775 →
Application:
07/796,917 →
Peptide Production
Patent:
5,476,995 →
Application:
07/931,864 →
Homologous Recombination in Mammalian Cells
Patent:
5,612,205 →
Application:
07/989,002 →
Parthenogenic Oocyte Activation
Patent:
5,496,720 →
Application:
08/016,703 →
Method of Cloning Bovine Embryos
Patent:
5,453,366 →
Application:
08/031,815 →
Method of Producing a Transgenic Bovine or Transgenic Bovine Embryo
Patent:
5,633,076 →
Application:
08/154,019 →
Dna Sequences to Target Proteins to the Mammary Gland for Efficient Secretion
Patent:
5,565,362 →
Application:
08/185,574 →
Targeted Synthesis of Protein in Mammary Gland of a Non-Human Transgenic Mammal
Patent:
5,994,616 →
Application:
08/186,836 →
Production of Fibrinogen in Transgenic Animals
Patent:
5,639,940 →
Application:
08/206,176 →
Transgenic Animals Secreting Desired Proteins into Milk
Patent:
6,727,405 →
Application:
08/246,259 →
Process for the Sterile Filtration of Milk
Patent:
5,576,040 →
Application:
08/282,256 →
Method for the Production of Biologically Active Polypeptides in a Mammal's Milk as Fusion Proteins That Are Less Active Than the Free Polypeptides, or Non-Active
Patent:
5,959,171 →
Application:
08/291,074 →
Genetic Construct of Which Protein Coding Dna Comprises Introns and Is Designed for Protein Production in Transgenic Animals
Patent:
5,861,299 →
Application:
08/343,884 →
Genetic Construct of Which Protein Coding Dna Comprises Introns and Is Designed for Protein Production in Transgenic Animals
Patent:
5,650,503 →
Application:
08/359,854 →
Alpha-Lactalbumin Gene Constructs
Patent:
5,852,224 →
Application:
08/381,691 →
Isolation of Lactoferrin from Milk
Patent:
5,919,913 →
Application:
08/406,271 →
Transgenic Non-Human Mammal Milk
Patent:
5,750,172 →
Application:
08/460,959 →
Transgenic Bovine
Patent:
5,741,957 →
Application:
08/461,333 →
Homologous Recombination in Mammalian Cells
Patent:
5,721,367 →
Application:
08/462,986 →
Transgenic Bovines and Milk from Transgenic Bovines
Patent:
6,013,857 →
Application:
08/464,167 →
Isolation of Lactoferrin from Milk
Patent:
5,849,885 →
Application:
08/464,182 →
Production of Human Recombinant Collagen in the Milk of Transgenic Mammals
Patent:
5,962,648 →
Application:
08/473,465 →
Parthenogenic Bovine Oocyte Activation
Patent:
5,843,754 →
Application:
08/473,794 →
Production of Recombinant Polypeptides by Bovine Species and Transgenic Methods
Patent:
6,140,552 →
Application:
08/476,798 →
Production of Collagen in the Milk of Transgenic Mammals
Patent:
6,713,662 →
Application:
08/482,173 →
Production of Human Recombinant Collagen in the Milk of Transgenic Animals
Patent:
5,895,833 →
Application:
08/485,194 →
Phenylalanine-Free Protein and Dna Coding Therefor
Parthenogenic Oocyte Activation
Patent:
6,194,202 →
Application:
08/610,744 →
Purification of Biologically Active Peptides from Milk
Patent:
6,268,487 →
Application:
08/648,235 →
Isolation of Lactoferrin from Milk
Patent:
5,861,491 →
Application:
08/693,274 →
Lysosomal Proteins Produced in the Milk of Transgenic Animals
Patent:
6,118,045 →
Application:
08/700,760 →
Piptide Production as Fusion Protein in Transgenic Mammal Milk
Patent:
6,211,427 →
Application:
08/727,153 →
Factor 1X Production in Transgenic Non-Human Mammals and Factor 1X Dna Sequences with Modified Splice Sites
Patent:
6,046,380 →
Application:
08/742,877 →
Production of Heterologous Protein in Milk of Transgenic Non-Human Mammals Comprising a Construct with an Intron
Patent:
6,548,735 →
Application:
08/781,518 →
Peptide Production as Fusion Protein in Transgenic Mammal Milk
Patent:
6,197,946 →
Application:
08/938,595 →
Useful Properties of Human Lactoferrin and Variants Thereof
Patent:
6,333,311 →
Application:
09/017,043 →
Purification of Alpha-1 Proteinase Inhibitor
Patent:
6,194,553 →
Application:
09/036,796 →
Production of Recombinant Polypeptides by Bovine Species and Transgenic Methods
Patent:
6,066,725 →
Application:
09/158,313 →
Parthenogenic Oocyte Activation
Patent:
6,077,710 →
Application:
09/176,395 →
Development of Normal Offspring Form Oocytes Injected with Freeze-Dried Spermatozoa
Patent:
6,641,526 →
Application:
09/177,391 →
Production of Fibrinogen in Transgenic Animals
Patent:
42,704 →
Application:
09/232,488 →
Production of Human Recombinant Collagen in the Milk of Transgenic Animals
Patent:
6,111,165 →
Application:
09/232,740 →
Method of Cloning Bovines Using Reprogrammed Non-Embryonic Bovine Cells
Patent:
6,011,197 →
Application:
09/239,922 →
Method of Producing a Polypeptide in an Ungulate
Patent:
6,395,958 →
Application:
09/354,276 →
Expression Methods
Patent:
6,525,241 →
Application:
09/355,295 →
Mammalian Transgenesis by Intracytoplasmic Sperm Injection
Patent:
6,376,743 →
Application:
09/371,648 →
Initiation of Full Mammalian Oocyte Activation by Multiple Sperm Components
Patent:
6,593,139 →
Application:
09/478,848 →
In Vitro Activation of Mammalian Oocytes
Patent:
6,680,199 →
Application:
09/576,592 →
Purification of Alpha-1 Proteinase Inhibitor
Patent:
6,525,176 →
Application:
09/612,592 →
Ungulates Produced by Sequential Nuclear Transfer
Patent:
6,603,059 →
Application:
09/688,782 →
Stabilisation of Milk from Transgenic Animals
Fusion Proteins Incorporating Lysozyme
C1 Inhibitor Produced in the Milk of Transgenic Non--Human Mammals
C1 Inhibitor with Short Half-Life Transient Treatment
Use of C1 Inhibitor for the Prevention of Ischemia-Reperfusion Injury
C1 Inhibitor with Short Half-Life Transient Treatment
Patent:
43,691 →
Application:
13/157,176 →
Use of C1 Inhibitor for the Prevention of Ischemia-Reperfusion Injury
Use of Anticoagulants in the Production of Recombinant Proteins in the Milk of Transgenic Animals
Use Of C1 Inhibitor For The Prevention Of Ischemia-Reperfusion Injury
Milking Device
Treatment of Hereditary Angioedema with C1 Inhibitor
Application:
15/122,130 →
Publication:
US 2016/0361394
Related Assignments
(13)
Other recorded transfers of the patents in this record — the chain of ownership.
Change of Name
Jul 18, 2013
From: GTC BIOTHERAPEUTICS, INC.
To: REVO BIOLOGICS, INC.
Reel/Frame 030831/0075 →
Corrective Assignment to Correct the Application Number 08232256 to 08282256 Previously Recorded on Reel 030831, Frame 0075. Assignors Hereby Confirms the Application Number.
Jul 31, 2013
From: GTC BIOTHERAPEUTICS, INC.
To: REVO BIOLOGICS, INC.
Reel/Frame 031012/0924 →
Corrective Assignment to Correct the Application Number 08232256, to 08282256, Previously Recorded on Reel 030831, Frame 0075.
Aug 13, 2013
From: GTC BIOTHERAPEUTICS, INC.
To: REVO BIOLOGICS, INC.
Reel/Frame 031161/0462 →
Change of Name
Aug 15, 2013
From: GTC BIOTHERAPEUTICS, INC.
To: REVO BIOLOGICS, INC.
Reel/Frame 031030/0152 →
Corrective Assignment to Correct the Assignment Recordation Previously Recoded on Reel 030831, Frame 0075. Assignors Hereby Confirms the Following Application Number Was Incorrectly Inputted as 08232256 and Confirms the Change of Name.
Aug 15, 2013
From: GTC BIOTHERAPEUTICS, INC.
To: REVO BIOLOGICS, INC.
Reel/Frame 031058/0292 →
Release of Security Interest
Mar 11, 2014
From: GENERAL ELECTRIC CAPITAL CORPORATION
To: GTC BIOTHERAPEUTICS, INC.
Reel/Frame 032424/0230 →
Release of Security Interest
Mar 14, 2014
From: LFB BIOTECHNOLOGIES S.A.S.U.
To: GTC BIOTHERAPEUTICS, INC.
Reel/Frame 032448/0045 →
Assignment of Assignor's Interest
May 8, 2014
From: REVO BIOLOGICS, INC.
To: LFB USA, INC.
Reel/Frame 032846/0099 →
Security Interest
Dec 7, 2016
From: PHARMING INTELLECTUAL PROPERTY B.V.
To: SILICON VALLEY BANK
Reel/Frame 040839/0865 →
Security Interest
Dec 7, 2016
From: PHARMING GROUP N.V.
To: SILICON VALLEY BANK
Reel/Frame 040594/0031 →
Amended and Restated Intellectual Property Security Agreement
May 16, 2017
From: PHARMING B.V.
To: ORBIMED ROYALTY OPPORTUNITIES II, LP
Reel/Frame 042481/0151 →
Amended and Restated Intellectual Property Security Agreement
May 16, 2017
From: PHARMING INTELLECTUAL PROPERTY B.V.
To: ORBIMED ROYALTY OPPORTUNITIES II, LP
Reel/Frame 042481/0139 →
Amended and Restated Intellectual Property Security Agreement
May 16, 2017
From: PHARMING GROUP N.V.
To: ORBIMED ROYALTY OPPORTUNITIES II, LP
Reel/Frame 042481/0051 →