Method and treatment with ketoprofen solution
A readily water-soluble ingestible form of ketoprofen is provided by the reaction of ketoprofen and any edible weak base to yield a palatable, stable, safe pharmaceutical solution for mass medication of animals. Any edible weak base such as sodium bicarbonate may be used with ketoprofen in a ratio of 10 to 1 by weight.
1. A method for the analgesic treatment of a livestock animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
2. The method of claim 1 , wherein the base is selected from the group consisting of sodium bicarbonate, sodium chloride, potassium chloride, sodium sulfate, and potassium sulfate.
3. The method of claim 1 wherein the flavoring agent is selected from the group consisting of cyclohexyl-sulfamic acid, saccharin (o-benzosulfimide), Aspartame (i.e., L-Aspartyl-L-phenylalanine methyl ester), and sugar.
4. A method for the treatment of rheumatoid arthritis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
5. A method for the treatment of osteoarthritis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
6. A method for the treatment of ankylosing spondylitis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
7. A method for the treatment of acute gouty arthritis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
8. A method for the treatment of acute tendinitis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
9. A method for the treatment of bursitis in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
10. A method for the treatment of primary dysmenorrhea in an animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, a flavoring agent, and an edible weak base: wherein said solution is administered to said animal in a non-encapsulated form.
11. The method of claim 1 , wherein the weight ratio of weak base to ketoprofen as about 10:1.
12. A method for the analgesic treatment of a livestock animal comprising administering to said animal a pharmaceutically effective amount of a palatable aqueous solution said solution consisting essentially of ketoprofen, water, and an edible weak base; wherein said solution is administered to said animal in a non-encapsulated form.
13. The method of claim 12 , wherein the weight ratio of weak base to ketoprofen is about 10:1.