IP Library Granted Patent US 6,912,415
Granted Patent B2
US 6,912,415 · App. 09/993,120 · Granted Jun 28, 2005

Method for acquiring MRI data from a large field of view using continuous table motion

Assignee: Mayo Foundation for Medical Education and Research
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Quick Facts
Patent No.
US 6,912,415
App. No.
09/993,120
Granted
Jun 28, 2005
Kind
B2
Abstract

MRA data is acquired from a large region of interest by translating the patient through the bore of the MRI system as a three-dimensional MRA data set are acquired. Patient table movement is controlled to track a bolus of contrast agent as it passes through the region of interest. Fluoroscopic images may be acquired during the scan to enable accurate bolus tracking. A seamless image of the entire region of interest is reconstructed.

Claims (81)

1. In a magnetic resonance imaging (MRI) system having a defined field of view (FOV), a method for producing an image of a subject over an extended field of view (FOV tot ) which is larger than the FOV, the steps comprising:

a) moving the subject through the MRI system such that the extended field of view (FOV tot ) passes through the defined field of view (FOV);

b) continuously acquire NMR data from the subject as it is moved through the FOV by repeatedly performing an imaging pulse sequence which acquires NMR data comprising a view of the subject using a readout gradient directed along the direction of subject movement;

c) adjusting each view acquired in step b) using subject position information;

d) storing each adjusted view in a data matrix; and

e) reconstructing an image using the data matrix.

2. The method as recited in claim 1 in which the MRI system has a table, and step a) is performed by:

i) placing the subject on the table; and

ii) moving the table.

3. The method as recited in claim 2 in which the table is moved continuously while performing step a).

4. The method as recited in claim 2 in which the table is moved at different velocities while performing step a).

5. The method as recited in claim 2 which includes:

injecting the subject with a contrast agent; and

in which the table is moved at a velocity which tracks the contrast agent as it moves through the extended field of view (FOV tot ).

6. The method as recited in claim 5 which includes:

reconstructing monitoring images during the performance of step a) from data stored in the data matrix.

7. The method as recited in claim 2 in which step c) includes adjusting the location in the data matrix in which the view is stored in step d) along the direction of subject movement as a function of the table location at the time the view is acquired in step b).

8. The method as recited in claim 2 in which step c) includes adjusting the phase of the NMR data in the view as a function of the table location at the time the view is acquired in step b).

9. The method as recited in claim 2 in which step b) further includes:

i) acquiring table location information as each view is acquired; and

the table location information is used in step c) to adjust each corresponding view.

10. The method as recited in claim 9 in which step c) includes:

i) performing a Fourier transformation of the NMR data in the view; and

ii) calculating a location in the data matrix for the transformed view as a function of the table location at the time the view was acquired in step b).

11. The method as recited in claim 1 in which step c) includes adjusting the location in the data matrix in which the view is stored in step d) along the direction of subject movement.

12. The method as recited in claim 1 in which step c) includes adjusting the phase of the NMR data in the view.

13. The method as recited in claim 1 in which step c) includes:

i) adjusting the phase of the NMR data in the view;

ii) Fourier transforming the phase adjusted NMR data in the view; and

iii) adjusting the location in the data matrix in which the Fourier transformed view is stored in step d) as a function of subject location at the time the view is acquired in step b) with respect to a subject reference location.

14. The method as recited in claim 1 in which step c) includes:

i) Fourier transforming the acquired view; and

ii) adjusting the location in the data matrix in which the Fourier transformed view is stored in step d) as a function of subject location at the time the view is acquired in step b) with respect to a subject reference location.

15. The method as recited in claim 1 in which the data matrix is a two-dimensional array of data.

16. The method as recited in claim 1 in which the data matrix is a three-dimensional array of data.

17. In a magnetic resonance imaging (MRI) system, the improvement comprising:

a) a table for supporting a subject and for moving the subject through a defined field of view (FOV) of the MRI system;

b) a pulse generator for operating the MRI system under the direction of a pulse sequence to continuously acquire a series of NMR data views of the subject as the subject is moved through the FOV using a readout gradient directed along the direction of table movement;

c) means for adjusting each acquired view as a function of subject location at the time the view is acquired with respect to a reference subject location;

d) a memory for storing the adjusted views as a data matrix; and

e) means for reconstructing an image from data in the data matrix which has a field of view in the direction of table motion which is larger than the defined FOV.

18. The improvement as recited in claim 17 in which element c) includes:

i) means for Fourier transforming each acquired view; and

ii) means for storing the Fourier transformed view in the data matrix at a location determined by the subject location at the time the view was acquired.

19. The improvement as recited in claim 17 which also includes:

f) means for reconstructing an image from data in the data matrix as the subject is moved through the defined FOV and views are being acquired.

20. The improvement as recited in claim 19 which also includes:

g) means for controlling the velocity of table motion as views are being acquired.

21. In a magnetic resonance imaging (MR) system having a defined field of view (FOV), a method for producing a three-dimensional image of a subject over an extended field of view (FOV tot ) which is larger than the FOV, the steps comprising:

a) moving the subject through the MRI system such that the extended field of view (FOV tot ) passes through the defined field of view (FOV);

b) continuously acquire NMR data from the subject as it is moved through the FOV by repeatedly performing a three-dimensional imaging pulse sequence which acquires NMR data comprising a view of the subject;

c) adjusting each view acquired in step b) using subject position information;

d) storing each view in a data matrix;

e) reconstructing two-dimensional monitor images as step b) is performed using adjusted data stored in the data matrix, each reconstructed monitor image covering substantially less than the extended field of view (FOV tot ); and

f) reconstructing an image over the extended field of view (FOV tot ) using the data matrix.

22. The method as recited in claim 21 in which the MRI system has a table, and step a) is performed by:

i) placing the subject on the table; and

ii) moving the table.

23. The method as recited in claim 22 which includes:

injecting the subject with a contrast agent;

and in which the table is moved at a velocity which tracks the contrast agent as it moves through the extended field of view (FOV tot ).

24. The method as recited in claim 23 in which table motion velocity is adjusted during the performance of steps a) and b) to better track the contrast agent as determined by the reconstructed monitor images.

25. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps comprising:

a) moving the subject through a defined field of view (FOV) of the MRI system along a motion axis;

b) continuously acquiring NMR data from the subject as the subject is moved along said motion axis through the FOV, the NMR data being acquired by:

i) producing an RF excitation pulse in the presence of a slab select gradient pulse to produce transverse magnetization in a three-dimensional volume having a thickness along a slab select gradient axis which is perpendicular to the motion axis;

ii) producing a phase encoding gradient pulse;

iii) acquiring an NMR signal in the presence of a readout gradient field directed along the axis of motion; and

iv) repeating steps i), ii) and iii) and cycling the phase encoding gradient pulse through a set of discrete values to acquire k-space data from the excited three-dimensional volume;

c) storing the acquired k-space data in a data matrix;

d) adjusting the data stored in the data matrix to offset the effect of table motion thereon; and

e) reconstructing an image from the adjusted data stored in the data matrix.

26. The method as recited in claim 25 in which step d) includes:

Fourier transforming data stored in the data matrix along the motion axis; and

shifting the storage location of the Fourier transformed data in the data matrix along the motion axis.

27. The method as recited in claim 25 which includes:

recording the location of the subject as each NMR signal is acquired; and

phase shifting the k-space data corresponding to each NMR signal by an amount determined by the subject location as the NMR signal was acquired.

28. The method as recited in claim 27 which includes:

Fourier transforming the k-space data corresponding to each NMR signal; and

shifting the storage location in the data matrix along the axis of motion of each Fourier transformed NMR signal by an amount determined by the subject location as the NMR signal was acquired.

Assignments (3)
CONFIRMATORY LICENSE Recorded Sep 5, 2008
From: MAYO FOUNDATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021491/0217 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 26, 2001
From: KRUGER, DAVID G.; RIEDERER, STEPHEN J.
To: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
Reel/Frame 012325/0617 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 1998
From: TRAN, KHANH
To: ADVANCED MICRO DEVICES, INC.
Reel/Frame 009216/0072 →
Continuity (2)
Provisional Application 6028255500 · Apr 9, 2001
Related Publication 20020173715A1 · Nov 21, 2002