Mitogenic oxygenase regulators
The present invention relates to new genes encoding for the production of novel nox enzyme proteins involved in generation of reactive oxygen intermediates that affect cell division. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.
1. An isolated nucleotide sequence wherein the sequence is SEQ ID NO:1.
2. An isolated nucleotide sequence encoding for a protein capable of stimulating superoxide production, wherein the nucleotide sequence comprises SEQ ID NO:1.
3. A vector, wherein the vector comprises the nucleotide sequence of claim 2 .
4. A cell containing the vector of claim 3 .
5. A vector, wherein the vector comprises the nucleotide sequence of SEQ ID NO:1.
6. A cell containing the vector of claim 5 .