IP Library Granted Patent US 6,976,639
Granted Patent B2
US 6,976,639 · App. 10/006,489 · Granted Dec 20, 2005

Apparatus and method for droplet steering

Assignee: EDC Biosystems, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 6,976,639
App. No.
10/006,489
Granted
Dec 20, 2005
Kind
B2
Abstract

An apparatus and method for droplet steering is disclosed herein. A throated structure having a nozzle defines a converging throat with an inlet and an outlet and a vectored fluid stream directed therethrough. The fluid stream is driven through the system via a vacuum pump. As the fluid approaches the outlet, its velocity increases and is drawn away from the nozzle through a connecting channel. As a droplet is ejected from a liquid therebelow, it will have a first trajectory until it is introduced to the high velocity fluid stream at the perimeter of the interior walls of the nozzle. The fluid accordingly steers the momentum of the droplet such that it obtains a second or corrected trajectory. Alternative variations include an electrically chargeable member, e.g., a pin, positionable to be in apposition to the outlet and capillary tubes for controlling the ejection surface of the pool of source fluid.

Claims (21)

1. A device for altering a trajectory of a droplet comprising:

a throated structure having a nozzle defined therethrough with an entrance port at a proximal end of the nozzle and an exit port at a distal end of the nozzle;

wherein the throated structure further defines at least one channel in fluid communication with the nozzle for receiving a flow of fluid such that the trajectory of the droplet entering the entrance port is alterable by the flow of fluid to a predetermined path as the droplet passes through the exit port;

wherein the distal end of the structure is cylindrically uniform in shape; and

wherein the cylindrically uniform distal end of the structure is 0.5–1 mm in length.

2. A device for altering a trajectory of a droplet comprising:

a throated structure having a nozzle defined therethrough with an entrance port at a proximal end of the nozzle and an exit port at a distal end of the nozzle;

wherein the throated structure further defines at least one channel in fluid communication with the nozzle for receiving a flow of fluid such that the trajectory of the droplet entering the entrance port is alterable by the flow of fluid to a predetermined path as the droplet passes through the exit port; and

wherein the throated structure is 1–150 mm in length.

3. A device for altering a trajectory of a droplet comprising:

a throated structure having a nozzle defined therethrough with an entrance port at a proximal end of the nozzle and an exit port at a distal end of the nozzle;

wherein the throated structure further defines at least one channel in fluid communication with the nozzle for receiving a flow of fluid such that the trajectory of the droplet entering the entrance port is alterable by the flow of fluid to a predetermined path as the droplet passes through the exit port; and

wherein the throated structure is attached to a movable platform configured to translate the throated structure in a planar direction relative to a wellplate disposed adjacently to the proximal end of the nozzle.

4. The device of claim 3 wherein the movable platform is configured to translate the throated structure in a planar direction over a distance of at least 2 mm.

5. The device of claim 3 wherein the movable platform is further configured to rotate the throated structure about a point centrally defined within the throated structure such that the proximal end of the nozzle is angularly disposable relative to the wellplate.

6. A device for altering a trajectory of a droplet comprising:

a plate having a first surface and a second surface, wherein the plate defines a plurality of throated nozzles therein, each nozzle having an entrance port defined in the first surface and an exit port defined in the second surface;

at least one channel defined within the device for receiving a flow of fluid therethrough, the channel being in fluid communication with and common to each nozzle such that the trajectory of a droplet entering the entrance port of any nozzle is alterable by the flow of fluid to a predetermined path as the droplet passes through the exit port; and

wherein the channel through which the fluid flows is defined between a well mask and the first surface, the well mask defining a plurality of orifices each located adjacent to a corresponding entrance port in the first surface.

7. The device of claim 6 wherein each orifice has a preconfigured diameter adapted to prevent the fluid from passing turbulently therethrough.

8. The device of claim 6 wherein each orifice is defined through a capillary tube extending from a surface of the well mask, each of the capillary tubes being adapted for insertion into a reservoir of liquid from which the droplet is ejected.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2020
From: EDC BIOSYSTEMS, INC.
To: LABCYTE INC.
Reel/Frame 052919/0062 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2002
From: WILLIAMS, ROGER O.; VAN TUYL, MICHAEL; FORBUSH, MICHAEL
To: EDC BIOSYSTEMS, INC.
Reel/Frame 012646/0902 →
Continuity (2)
Provisional Application 6034842900 · Oct 29, 2001
Related Publication 20030080208A1 · May 1, 2003