Antibody specific for a DNA repair protein
View Patent ↗An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.
1. An isolated, purified antibody or a fragment thereof that specifically binds to a human DNA double strand break repair polypeptide having a molecular weight of 95000 Da as determined by SDS-PAGE wherein the polypeptide comprises SEQ ID NO:2.
2. The antibody of claim 1 which is a polyclonal antibody.
3. The antibody of claim 1 which is a monoclonal antibody.
4. The antibody of claim 1 which binds to amino acids 399–751 of SEQ ID NO:2.
5. The antibody of claim 1 which binds to a polypeptide consisting of SEQ ID NO:2.