Antagonists of neuropilin receptor function and use thereof

Assignee: Children's Medical Center Corporation

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Quick Facts

Patent No.: US 7,731,959
App. No.: 10/104,440
Granted: Jun 8, 2010
Kind: B2

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Abstract

The present invention relates to antagonists of neuropilin receptor fuction and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases.

Claims (1)

1. A method of inhibiting angiogenesis in a host in need thereof which comprises administering to said host an effective amount of an antibody that binds a neuropilin-1 (NP-1) having the amino acid sequence set forth in SEQ ID NO:2.

Assignments (4)

CONFIRMATORY LICENSE Recorded Apr 10, 2020

From: BOSTON CHILDREN'S HOSPITAL

To: NIH-DEITR

Reel/Frame 052367/0814 →

CONFIRMATORY LICENSE Recorded Jun 21, 2010

From: CHILDREN'S HOSPITAL (BOSTON)

To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT

Reel/Frame 024564/0434 →

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2010

From: KLAGSBRUN, MICHAEL; SOKER, SHAY; MIAO, HUA-QUAN

To: CHILDREN'S MEDICAL CENTER CORPORATION