IP Library Granted Patent US 7,261,909
Granted Patent B2
US 7,261,909 · App. 10/165,411 · Granted Aug 28, 2007

Method of obtaining a hydroxytyrosol-rich composition from vegetation water

Assignee: Creagri, Inc.
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Quick Facts
Patent No.
US 7,261,909
App. No.
10/165,411
Granted
Aug 28, 2007
Kind
B2
Abstract

The invention provides olive-derived hydroxytyrosol. According to one aspect of the invention, vegetation water is collected from olives. Acid is added to stabilize the vegetation water and prevent fermentation. The mixture is incubated to allow oleoeuropein to convert to hydroxytyrosol, and then fractionated to separate hydroxytyrosol from other components. The hydroxytyrosol is useful as a natural anti-bacterial, anti-viral and fungicidal product for agricultural and pest control applications. In addition, it is useful as a therapeutic and anti-oxidant for a variety of health purposes.

Claims (12)

1. A method of producing a hydroxytyrosol-rich composition, comprising

(a) producing vegetation water from olives;

(b) adding acid to the vegetation water in an amount effective to produce a pH between about 1 and about 5; and

(c) incubating the acidified vegetation water for a period of at least two months, until at least 75% of oleuropein originally present in the vegetation water has been converted to hydroxytyrosol.

2. The method of claim 1 , wherein said incubating is carried out for a period of at least 9 months, and until at least 90% of oleuropein originally present in the vegetation water has been converted to hydroxytyrosol.

3. The method of claim 1 , wherein the vegetation water is produced from depitted olive meat.

4. The method of claim 3 , wherein the incubating is carried out until the vegetation water has a weight ratio of hydroxytyrosol to oleuropein of between about 5:1 and about 200:1.

5. The method of claim 4 , wherein the incubating is carried out until the vegetation water has a weight ratio of hydroxytyrosol to oleuropein of between about 10:1 and about 100:1.

6. The method of claim 3 , wherein the incubating is carried out until the vegetation water has a weight ratio of hydroxytyrosol and tyrosol of between about 3:1 and about 50:1.

7. The method of claim 6 , wherein the incubating is carried out until the vegetation water has a weight ratio of hydroxytyrosol and tyrosol of between about 5:1 to about 30:1.

8. The method of claim 1 , which further comprises fractionating the incubated vegetation water to separate hydroxytyrosol from other components.

9. The method of claim 1 , wherein said acid is added in an amount effective to produce a pH between about 2 and about 4.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 27, 2023
From: CARR & FERRELL LLP; VALDEVIT, EZIO
To: HIDROX, LLC
Reel/Frame 065045/0622 →
SECURITY INTEREST Recorded Mar 1, 2023
From: 2199933 ONTARIO INC.
To: CARR AND FERRELL LLP; VALDEVIT, EZIO
Reel/Frame 062837/0081 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2019
From: CALISCANA, LLC
To: OLIPHENOL, LLC
Reel/Frame 048464/0225 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2019
From: CREAGRI, INC.
To: CREA, ROBERTO
Reel/Frame 048460/0378 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 27, 2019
From: CREA, ROBERTO
To: CALISCANA, LLC
Reel/Frame 048460/0767 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 29, 2011
From: CREA, ROBERTO
To: CREAGRI, INC.
Reel/Frame 027293/0695 →
Continuity (3)
Division 0994474400 · Aug 31, 2001
Provisional Application 6023053500 · Sep 1, 2000
Related Publication 20020198415A1 · Dec 26, 2002