Device and method for combining a treatment agent and a gel
A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site.
1. A method comprising:
introducing a first material comprising a treatment agent at a treatment site within a mammalian host; and
introducing a second material, the second material comprising a property of a bioerodable gel at the treatment site,
wherein the treatment site comprises a periadventitial site or a site radially outward of a periadventitial site and the treatment site is accessed through a blood vessel.
2. The method of claim 1 , wherein the first material and the second material are introduced separately as a combination.
3. The method of claim 1 , wherein the second material is a product of a combination of a first component and a second component and one of the first component and the second component comprises the first material.
4. The method of claim 3 , wherein introducing the second material comprises:
introducing a delivery device having a first delivery port and a second separate delivery port, the first delivery port and the second delivery port arranged in one of a co-linear and a co-axial arrangement; and
introducing the first component to the treatment site through the first delivery port; and
introducing the second component to the treatment site through the second delivery port.
5. The method of claim 1 , wherein introducing the first material comprises:
advancing a delivery device a distance into a wall of the blood vessel to the treatment site; and
after advancing the delivery device, introducing the first material through the delivery device.
6. The method of claim 1 , wherein the treatment site is a periadventitial site.
7. The method of claim 1 , wherein introducing the second material follows the introduction of the first material.
8. The method of claim 1 , wherein introducing the second material precedes the introduction of the first material.
9. The method of claim 4 , wherein the treatment site is selected from the group consisting of a thoroscopic surgery site, an orthoscopic surgery site, and a laparoscopic surgery site.
10. A method comprising:
positioning a delivery device at a location in a blood vessel;
advancing the delivery device a distance into a wall of the blood vessel to a treatment site; and
after advancing the delivery device, introducing a first material comprising a treatment agent and a second material comprising a property of a bioerodable gel at the treatment site.
11. The method of claim 10 , wherein the first material and the second material are introduced as a combination.
12. The method of claim 11 , wherein the second material is a product of a combination of a first component and a second component and one of the first component and the second component comprises the first material.
13. The method of claim 12 , wherein introducing the second material comprises:
introducing a delivery device having a first delivery port and a second separate delivery port, the first delivery port and the second delivery port arranged in one of a co-linear and a co-axial arrangement; and introducing the first component to the treatment site through the first delivery port; and introducing the second component to the treatment site through the second delivery port.
14. The method of claim 13 , wherein the treatment site is associated with a blood vessel.
15. The method of claim 14 , wherein introducing the first material comprises:
advancing the delivery device a distance into a wall of the blood vessel to the treatment site; and
after advancing the delivery device, introducing the first material through the delivery device.
16. The method of claim 15 , wherein the treatment site comprises a location, with reference to a lumen of the blood vessel, beyond the medial layer of the blood vessel.
17. The method of claim 16 , wherein the treatment site comprises a periadventitial site.
18. The method of claim 10 , wherein introducing the second material follows the introduction of the first material.
19. The method of claim 10 , wherein introducing the second material precedes the introduction of the first material.