Pharmaceutical formulations of modafinil
The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
1. A composition comprising modafinil, wherein modafinil comprises about 90% by weight of the composition; a lactose monohydrate, which comprises about 3-10% of the composition by weight; a cross-linked sodium carboxymethyl cellulose, which comprises about 2-5% of the composition by weight; a polyvinyl pyrrolidone, which comprises about 2-5% of the composition by weight; and magnesium stearate, which comprises about 0.2-2.0% of the composition by weight.
2. The composition of claim 1 , wherein modafinil is the levorotatory isomer of modafinil.
3. A composition comprising modafinil, wherein modafinil comprises 70-80% of the composition by weight; a lactose monohydrate from about 3-20% of the composition by weight; a cross-linked sodium carboxymethyl cellulose from about 2-10% of the composition by weight; a polyvinyl pyrrolidone from about 2-10% of the composition by weight, and magnesium stearate from about 0.2-2.0% of the composition by weight.
4. The composition of claim 3 , wherein modafinil is the levorotatory isomer of modafinil.