Method for antagonizing inhibition effects of alcohol on cell adhesion

Assignees: President and Fellows of Harvard College; The United States of America as represented by the United States Department of Veterans Affairs

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Quick Facts

Patent No.: US 6,977,272
App. No.: 10/270,551
Granted: Dec 20, 2005
Kind: B2

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Abstract

A method of antagonizing inhibition effects of alcohol on cell adhesion is disclosed comprising contacting a cell-adhesion molecule expressing cell with an effective amount of a compound, wherein the compound comprises an alcohol selected from the group consisting of 3-pentanol, 2-pentanol, cyclopentanol, 4-methyl-1-pentanol, 2-methyl-2-pentanol, and 2,6-diisopropylphenol.

Claims (7)

1. A method of antagonizing alcohol inhibition effects on cell adhesion, comprising:

contacting a cell-adhesion molecule expressing cell with an effective amount of a compound; and

wherein the compound comprises an alcohol selected from the group consisting of 3-pentanol, 2-pentanol, cyclopentanol, 4-methyl-1-pentanol, 2-methyl-2-pentanol, and 2,6-diisopropylphenol.

2. The method of claim 1 , wherein:

said cell-adhesion molecule comprises L1 molecule.

3. The method of claim 1 , wherein:

said cell-adhesion molecule expressing cell comprises a neural or fibroblast cell.

Assignments (3)

CONFIRMATORY LICENSE Recorded Nov 8, 2021

From: HARVARD UNIVERSITY

To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT

Reel/Frame 058044/0865 →

CONFIRMATORY LICENSE Recorded Feb 27, 2019

From: PRESIDENT AND FELLOWS OF HARVARD COLLEGE

To: NIH - DEITR