IP Library Granted Patent US 7,070,997
Granted Patent B2
US 7,070,997 · App. 10/340,813 · Granted Jul 4, 2006

Isolated nucleotides encoding tomato senescence-induced eIF-5A

Assignee: Senesco, Inc.
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Quick Facts
Patent No.
US 7,070,997
App. No.
10/340,813
Granted
Jul 4, 2006
Kind
B2
Abstract

Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.

Claims (8)

1. A vector comprising a DNA molecule encoding

(a) a tomato senescence-induced eIF-5A, wherein the DNA molecule is at least 70% homologous to SEQ ID NO:11, and wherein the senescence-induced eIF-5A has translation initiation factor activity; and

(b) regulatory sequences operatively linked to the DNA molecule such that eIF-5A is expressed in a plant cell into which it is transformed.

2. A transgenic plant cell comprising the vector according to claim 1 .

3. A vector comprising a DNA molecule encoding (a) senescence-induced eIF-5A, wherein the DNA molecule comprises SEQ ID NO:11; and (b) regulatory sequences operatively linked to the DNA molecule such that the eIF-5A is expressed in a plant cell into which it is transformed.

4. A transgenic plant cell comprising the vector according to claim 3 .

5. An isolated DNA molecule encoding tomato senescence-induced eIF-5A, wherein the DNA molecule has at least 70% sequence identity with SEQ ID NO:11 and wherein the senescence-induced eIF-5A has translation initiation factor activity.

6. An isolated DNA molecule encoding tomato senescence-induced eIL-5A, wherein the DNA molecule comprises SEQ ID NO:11.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2016
From: THOMPSON, JOHN E.; WANG, TZANN-WEI; LU, DONGEN LILY
To: SENESCO, INC.
Reel/Frame 039417/0250 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2016
From: SENESCO, INC.
To: AGRIBODY TECHNOLOGIES, INC.
Reel/Frame 039417/0254 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Mar 25, 2010
From: YA GLOBAL INVESTMENTS, L.P.
To: SENESCO TECHNOLOGIES, INC.; SENESCO, INC.
Reel/Frame 024128/0676 →
SECURITY AGREEMENT Recorded Feb 5, 2008
From: SENESCO TECHNOLOGIES, INC.; SENESCO, INC.
To: YA GLOBAL INVESTMENTS, L.P.
Reel/Frame 020468/0001 →
Continuity (3)
Division 0959777100 · Jun 19, 2000
Continuation In Part 0934867500 · Jul 6, 1999
Related Publication 20030115636A1 · Jun 19, 2003