Use of polyphenols to treat skin conditions
View Patent ↗A composition is provided to treat and/or prevent for treating skin conditions including fine lines and wrinkles, acne rosacea, surface irregularities of the skin and hyper-pigmentation melasma of the skin, which includes use of a topically applied composition such as an ointment, lotion, cream, serum, gel or pad applied formulation, containing an effective amount of polyphenols, such as green tea based polyphenols, including but not limited to catechins, such as epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicathechin 3-gallate (ECG) and epicatechin (EC). The formulation is preferably composed of 90 percent polyphenol isolates, derived from green tea with potent antioxidant properties, to assist in minimizing free-radical induced skin damage.
1. A method of treating fine lines and wrinkles in skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a cream having the following ingredients with said ingredients being provided in the below listed percentage by weight:
Ingredient
%
Water
87.57
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Lecithin
5.00
Behenyl Alcohol
1.00
Stearic Acid
0.10
Sodium Hyaluronate
0.01
Glyceryl Stearate
1.00
C12-16 Alcohols
1.00
Germall II
0.30
Palmitic Acid
1.00
Bisabolol
0.10
Polysorbate 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10
Soy Phospholipids
0.25;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
2. A method of treating fine lines and wrinkles in skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
96.92
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Sodium Hyaluronate
0.01
Germall II
0.30
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
3. A method of treating acne rosacca of the skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application contaning a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a cream having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
87.57
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Lecithin
5.00
Behenyl Alcohol
1.00
Stearic Acid
0.10
Sodium Hyaluronate
0.01
Glyceryl Stearate
1.00
C12-16 Alcohols
1.00
Germall II
0.30
Palmitic Acid
1.00
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10
Soy Phospholipids
0.25;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
4. A method of treating acne rosacca of the skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
96.92
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Sodium Hyaluronate
0.01
Germall II
0.30
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
5. A method of treating skin surface irregularities and acne scars in skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
87.57
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Lecithin
5.00
Behenyl Alcohol
1.00
Stearic Acid
0.10
Sodium Hyaluronate
0.01
Glyceryl Stearate
1.00
C12-16 Alcohols
1.00
Germall II
0.30
Palmitic Acid
1.00
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10;
Soy Phospholipids
0.25;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
6. A method of treating skin surface irregularities and acne scars in skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
96.92
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Sodium Hyaluronate
0.01
Germall II
0.30
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
7. A method of treating hyper-pigmentation melasma of the skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a cream having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
87.57
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Lecithin
5.00
Behenyl Alcohol
1.00
Stearic Acid
0.10
Sodium Hyaluronate
0.01
Glyceryl Stearate
1.00
C12-16 Alcohols
1.00
Germall II
0.30
Palmitic Acid
1.00
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10
Soy Phospholipids
0.25;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
8. A method of treating hyper-pigmentation melasma of the skin by topical application, consisting essentially of the steps of:
a. preparing a composition for topical application containing a therapeutically effective amount of at least one polyphenol derived from green tea dispersed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
96.92
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Sodium Hyaluronate
0.01
Germall II
0.30
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10;
b. topically applying said composition to the skin to be treated; and
c. periodically repeating said topical application.
9. A topically applied composition for treating fine lines and wrinkles in skin, acne rosacea, surface irregularities of the skin and hyperpigmentation melasma of the skin consisting essentially of at least one polyphenol compound derived from green tea dispensed in a suitable dermatologically acceptable vehicle, said composition comprises a cream having the following ingredients with said ingredients being provided in the below listed percentage by weight:
Ingredient
%
Water
87.57
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Lecithin
5.00
Behenyl Alcohol
1.00
Stearic Acid
0.10
Sodium Hyaluronate
0.01
Glyceryl Stearate
1.00
C12-16 Alcohols
1.00
Germall II
0.30
Palmitic Acid
1.00
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10
Soy Phospholipids
0.25.
10. A topically applied composition for treating fine lines and wrinkles in skin, acne rosacea, surface irregularities of the skin and hyperpigmentation melasma of the skin consisting essentially of at least one polyphenol compound derived from green tea dispensed in a suitable dermatologically acceptable vehicle, said composition comprising a serum having the following ingredients present in the below-listed percentage by weight:
Ingredient
%
Water
96.92
Carbomer
0.40
Methylparaben
0.10
Tetrasodium EDTA
0.12
Triethanolamine
0.50
Sodium Hyaluronate
0.01
Germall II
0.30
Bisabolol
0.10
Polysorbate - 20
0.20
90% Polyphenol Green Tea Extract
0.25
Cucumber Extract
1.00
Chamomile Extract
0.10.