Cyclohexyl(alkyl)-propanolamines, preparation method and pharmaceutical compositions containing same

The present invention relates to the compounds of formula (I): in which A is a group of formula (a) or (b) in which R represents a hydrogen or halogen atom, an —S(O) z (C 1 –C 4 )alkyl group, an —NHSO 2 (C 1 –C 4 )alkyl group, an —SO 2 NH(C 1 –C 4 )alkyl group, an —NHSO 2 phenyl-(C 1 –C 4 )alkyl group or an —NHSO 2 phenyl group, said phenyl possibly being substituted with a halogen atom, with a (C 1 –C 4 )alkyl group or with a (C 1 –C 4 )alkoxy group; R 1 represents a hydrogen atom or a (C 1 –C 4 )alkyl group, a —CO(C 1 –C 4 )alkyl group, a phenyl-(C 1 –C 4 )alkyl group or a —COphenyl group, said phenyl also possibly being substituted with a halogen atom or with a (C 1 –C 4 )alkoxy group; R 2 is a hydrogen atom or an —SO 2 (C 1 –C 4 )alkyl group, an —SO 2 phenyl-(C 1 –C 4 )alkyl group or an —SO 2 phenyl group; X completes a ring of 5 to 8 atoms, said ring being saturated or unsaturated, possibly being substituted with one or two (C 1 –C 4 )alkyl groups and bearing one or two carbonyl groups; n, m and z are, independently, 0, 1 or 2; R 3 represents a hydrogen or halogen atom, a (C 1 –C 6 )alkyl group, a (C 1 –C 4 )alkoxy group, a —COO(C 1 –C 4 )alkyl group, a —CO(C 1 –C 4 )alkyl group, an —NHSO 2 (C 1 –C 4 )alkyl group, an —NHSO 2 phenyl-(C 1 –C 4 )alkyl groups, —NO 2 , —CN, —CONR 4 R 5 , —COOH, or a 4,5-dihydro-1,3-oxazol-2-yl or 4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl group; R 4 and R 5 represent, independently, a hydrogen atom, a phenyl, a (C 1 –C 4 )alkyl group or a phenyl-(C 1 –C 4 )alkyl group or R 4 and R 5 with the nitrogen atom to which they are attached, may form a ring of 5 to 7 atoms in total; and to the salts or solvates thereof, to the pharmaceutical compositions containing them, to a process for the preparation thereof and to intermediates in this process.