IP Library › Granted Patent US 7,201,904
Granted Patent B2
US 7,201,904 · App. 10/440,390 · Granted Apr 10, 2007

Epitopes of hepatitis C virus

Assignee: The General Hospital Corporation
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Quick Facts
Patent No.
US 7,201,904
App. No.
10/440,390
Granted
Apr 10, 2007
Kind
B2
Abstract

The invention provides compositions containing HCV epitopes, which are recognized by cytotoxic T lymphocytes. Such polypeptides are used in prophylactic vaccines, immunotherapies, and assays to monitor the progress or success of immune interventions. The compositions are optimized to elicit an immune response in a genetically-diverse population of individuals.

Claims (2)

1. An immunogenic composition comprising a purified Hepatitis C Virus (HCV) polypeptide, wherein said HCV polypeptide is HLA-Cw7 restricted and consists of the amino acid sequence of SEQ ID NO:52.

2. An immunogenic composition comprising a purified Hepatitis C Virus (HCV) polypeptide, wherein said HCV polypeptide is HLA-A29 restricted and consists of the amino acid sequence of SEQ ID NO:51.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jun 13, 2017
From: PARTNERS HEALTHCARE INNOVATION
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 042692/0831 →
CONFIRMATORY LICENSE Recorded Aug 6, 2008
From: GENERAL HOSPITAL CORPORATION DBA MASS
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021344/0087 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 29, 2003
From: LAUER, GEORG; OUCHI, LEI; WALKER, BRUCE D.
To: GENERAL HOSPITAL CORPORATION, THE
Reel/Frame 014537/0539 →
Continuity (2)
Provisional Application 6038127300 · May 16, 2002
Related Publication 20040105868A1 · Jun 3, 2004