Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria
A preventive and/or therapeutic agent for dysuria, which comprises as an effective ingredient a cyclohexenone long-chain alcoholic derivative represented by the following formula (1): [wherein, R 1 , R 2 and R 3 each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C 10-28 alkylene or alkenylene group]. This compound alleviates dysuria due to hypofunction of the urinary bladder so that they are useful as a preventive and/or therapeutic agent for dysuria
1. A method of preventing or treating dysuria due to hypofunction of a functioning urinary bladder in a subject in need of such prevention or treatment, which comprises administering an effective amount of a cyclohexenone long-chain alcoholic derivative, represented by the following formula (I):
wherein R 1 , R 2 and R 3 each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C 10-28 alkylene or alkenylene group or a salt solvate or hydrate thereof.
2. A method of treating dysuria in a patient in need of treatment which comprises administering an effective amount of the compound of formula (1) as defined in claim 1 to the patient.
3. The method of claim 2 , wherein said patient is a human being.
4. The method of claim 3 , wherein said administering is through an oral route.
5. The method of claim 3 wherein said administering is through a parenteral route.
6. The method of claim 3 wherein said effective amount is 0.01 to 1,000 mg/day for an adult human.
7. The method of claim 1 , wherein said compound of formula (1) is 3-(15-Hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one.