Transcutaneous immunization against papillomavirus with papillomavirus virus-like particles
The present invention relates to a method of vaccinating a mammal against papillomavirus by administering papillomavirus virus-like particles transdermally to a mammal under conditions effective to induce an immune response to the papillomavirus.
1. A method of inducing an immune response in a mammal against papillomavirus comprising:
administering papillomavirus virus-like particles transcutaneously to a mammal under conditions effective to induce an immune response to the papillomavirus.
2. The method according to claim 1 further comprising:
administering one or more vaccine booster inoculations of papillomavirus virus-like particles to the mammal.
3. The method according to claim 2 , wherein said booster inoculation is administered parenterally, transdermally, or orally.
4. The method according to claim 3 , wherein the booster is orally administered.
5. The method according to claim 3 , wherein the booster is parenterally administered.
6. The method according to claim 3 , wherein the booster is transdermally administered.
7. The method according to claim 1 , wherein the immune response is an immune response which will protect the mammal from infection by papillomavirus.
8. The method according to claim 1 , wherein the papillomavirus is a human papillomavirus.
9. The method according to claim 8 , wherein the human papillomavirus is Human Papillomavirus Type 6.
10. The method according to claim 8 , wherein the human papillomavirus is Human Papillomavirus Type 11.
11. The method according to claim 8 , wherein the human papillomavirus is Human Papillomavirus Type 16.
12. The method according to claim 8 , wherein the human papillomavirus is Human Papillomavirus Type 18.
13. The method according to claim 8 , wherein the papillomavirus virus-like particles are administered with a pharmaceutically acceptable carrier.