Quinoline derivatives, process for preparing them and use for the treatment of diseases mediated by s-CD23
A compound of formula (I): useful in the treatment and prophylaxis of conditions mediated by s-CD23
1. A compound of formula (I):
2. A compound of formula (IA):
3. A pharmaceutical composition which comprises a compound according to claim 1 and optionally a pharmaceutically acceptable carrier therefor.
4. A process for preparing a compound according to claim 1 which process comprises:
(a) deprotecting a compound of formula (II):
wherein P is a protecting group selected from the group consisting of benzyl, tetrahydropyranyl and p-methoxybenzyl, or
(b) formylating a compound of formula (III):
or (c) oxidising a compound of formula (X):
5. A compound of formula (II):
wherein P is a protecting group selected from the group consisting of benzyl, tetrahydropyranyl and p-methoxybenzyl.
6. A compound of formula (III):
7. A compound of formula (X):