Device for protein crystallisation
The invention relates to a container ( 1 ) with a base body ( 2 ), comprising a base plate ( 3 ) and side walls ( 4 ) standing out therefrom in an at least approximately perpendicular arrangement, and with wells ( 5 ) disposed in the base body ( 2 ). The wells ( 5 ) are provided in the form of a recess in the base plate ( 3 ) and the side walls ( 4 ) of the base plate ( 3 ) are disposed in at least the approximately opposite direction from the recesses in order to accommodate a volume.
1. A container comprising a base body consisting of a base plate and side walls standing up therefrom in an at least almost perpendicular arrangement, wells disposed in the base body which are provided in the form of a recess in the base plate, the side walls being disposed in an at least substantially opposite direction from the recesses in order to accommodate a volume of the container, and a lattice-type unit within the container for sub-dividing the volume into part-regions.
2. The container as claimed in claim 1 , wherein the wells are arranged in a uniform pattern.
3. The container as claimed in claim 1 , comprising 6, 12, 24, 48, 96, 384 or 1536 wells.
4. The container as claimed in claim 1 , wherein the wells are of a conical or cylindrical design.
5. The container as claimed in claim 2 , wherein the wells have a capacity selected from a range with a lower limit of 0.01 μl, and an upper limit of 50 μl.
6. The container as claimed in claim 1 , wherein the wells have bases disposed in a plane parallel with a container support surface.
7. The container as claimed in claim 1 , wherein the base plate and the wells are disposed in a plane parallel with a container support surface.
8. The container as claimed in claim 1 , wherein the wells are surface treated with aldehyde, silane, epoxy, thiol, polyethylene glycol (PEG), polyoxyethylene-sorbitan-monolaureate, magnetic materials, streptavidin or biotin.
9. The container as claimed in claim 1 , wherein the wells are square, rectangular, conical or semi-spherical as seen from a side view.
10. The container as claimed in claim 1 , wherein the wells are round, quadrangular, hexagonal, octagonal or in the shape of a parallelogram as seen in top view.
11. The container as claimed in claim 1 , wherein the base plate between the wells is at least partially non-transparent.
12. The container as claimed in claim 1 , wherein the surface of the base plate between the wells is surface-treated with a hydrophobic substance or has a hydrophobic mask applied to it.
13. The container as claimed in claim 1 , wherein the base body is made from a material selected from a group consisting of polypropylene, polystyrene, acrylo-butadiene-styrene, polyamide, polycarbonate, polymethyl methacrylate, polysulphone, cyclo-olefin copolymer, polymethyl pentene and/or styrene-acrylonitrile.
14. The container as claimed in claim 1 , wherein the base body is made from several different materials.
15. The container as claimed in claim 1 , wherein a co-ordinate marker is provided for indicating the layout of the wells in the base plate.
16. The container as claimed in claim 1 , wherein the base body is preferably made by an injection-moulding process.
17. The container as claimed in claim 1 , wherein a recess is provided on a longitudinal side and/or on a transverse of the base body.
18. The container as claimed in claim 1 , comprising at least one retaining element on the side walls of the container for a lattice-type unit.
19. The container as claimed in claim 1 , wherein webs of the lattice-type unit are surrounded by a frame.
20. The container as claimed in claim 1 , comprising spacers on the bottom face of the lattice-type units to establish a flow connection between the part-regions.
21. The container as claimed in claim 19 , wherein the webs of the lattice-type units are disposed at right-angles to one another.
22. The container as claimed in claim 19 , wherein the height of the lattice-type units in intersecting regions of the webs is one third to a half higher than it is between the intersecting regions.
23. The container as claimed in claim 19 , wherein the webs and/or the frame are of identical height.
24. The container as claimed in claim 19 , wherein the frame has spacers for holding the lattice-type units at a distance from the side walls of the container.
25. The container as claimed in claim 1 , wherein the external dimensions are slightly smaller than the dimensions of the container.
26. The container as claimed in claim 1 , wherein made from a material selected from a group consisting of polypropylene, polystyrene, acrylo-butadiene-styrene, polyamide, polycarbonate, polymethyl methacrylate, polysulphone, cylo-olefin copolyrmer, polymethyl pentene and/or styrene-acrylo-nitrile.
27. The container as claimed in claim 1 , wherein the wells are at least partially of a transparent synthetic resin.