Process for the preparation of phenyl pyrazole compounds
View Patent ↗A process for the preparation of compound (III) which comprises the reaction between a compound of general formula (V) and dicyano acetylene (IV), said reaction carried out in the presence of water (IV), (V), (III) wherein R is selected from CF 3 , or C 1 to C 6 alkyl M is an alkaline or alkaline-earth metal or silver
1. A process for the preparation of compound (III) which comprises the reaction between a compound of general formula (V) and dicyano acetylene (IV), said reaction carried out in the presence of water
wherein R is selected from CF 3 , or C 1 to C 6 alkyl and
M is an alkaline or alkaline-earth metal or silver.
2. A process as claimed in claim 1 wherein R is CF 3 and M is silver.
3. A process as claimed in claim 1 carried out in the presence of an organic solvent which is miscible with water.
4. A process as claimed in claim 3 in which the solvent is acetone or tetrahydrofuran.
5. A process as claimed in claim 1 carried out at a temperature of from −100 to +50° C.
6. A process as claimed in claim 1 carried out wherein the molar ratio of dicyano acetylene to the compound of formula (V) is from 5:1 to 1:5.
7. A process as claimed in claim 2 carried out in the presence of an organic solvent which is miscible with water.