Pre-filled columns for flash chromatography with higher separating efficiency
A column for flash chromatography having spherical, or semi-spherical, and porous silica gel having a granule size between 3 and 45 μm and pores between 30 and 300 Å.
1. A method for purifying a product comprising:
performing a flash chromatography process by:
introducing an eluent with at least one product to be purified into a flash chromatography column pre-filled with a spherical and porous silica gel having particle size between 3 and 45 μm and pores between 30 and 300 Å;
causing the eluent to flow through the pre-filled column; and
obtaining a separation of the at least one product to be purified.
2. The method of purifying a product of claim 1 wherein the flash chromatography column contains between 10 mg to 1 kg of the spherical and porous silica gel.
3. The method for purifying a product according to claim 1 wherein the flash chromatography column is adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.
4. A method for purifying a product comprising:
performing a flash chromatography process by:
introducing an eluent with at least one product to be purified into a flash chromatography column pre-filled with a semi-spherical and porous silica gel having particle size between 3 and 45 μm and pores between 30 and 300 Å;
causing the eluent to flow through the pre-filled column; and
obtaining a separation of the at least one product to be purified.
5. The method for purifying a product of claim 4 wherein the flash chromatography column contains between 10 mg to 1 kg of the semispherical and porous silica gel.
6. The method for purifying a product according to claim 4 wherein the flash chromatography column is adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.
7. A pre-filled flash chromatography column for purifying a product, comprising
a plastic tube or syringe body; and
spherical and porous raw silica gel having particle size predominantly between 3 and 45 μm and pores between 30 and 300 Å placed inside the plastic tube or syringe body.
8. The pre-filled flash chromatography column according to claim 7 wherein the flash chromatography column contains between 10 mg to 1 kg of the spherical and porous silica gel.
9. The pre-filled flash chromatography column according to claim 7 adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.
10. A pre-filled flash chromatography column for purifying a product, comprising
a plastic tube or syringe body; and
semi-spherical and porous raw silica gel having particle size predominantly between 3 and 45 μm and pores between 30 and 300 Å placed inside the plastic tube or syringe body.
11. The pre-filled flash chromatography column according to claim 10 wherein the flash chromatography column contains between 10 mg to 1 kg of the semispherical and porous silica gel.
12. The pre-filled flash chromatography column according to claim 10 adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.
13. A pre-filled flash chromatography column for purifying a product, comprising
a low-pressure glass tube or syringe body; and
spherical and porous raw silica gel having particle size predominantly between 3 and 45 μm and pores between 30 and 300 Å placed inside the low-pressure glass tube or syringe body.
14. The pre-filled flash chromatography column according to claim 13 wherein the flash chromatography column contains between 10 mg to 1 kg of the spherical and porous silica gel.
15. The pre-filled flash chromatography column according to claim 13 adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.
16. A pre-filled flash chromatography column for purifying a product, comprising
a low-pressure glass tube or syringe body; and
semi-spherical and porous raw silica gel having particle size predominantly between 3 and 45 μm and pores between 30 and 300 Å placed inside the low-pressure glass tube or syringe body.
17. The pre-filled flash chromatography column according to claim 16 wherein the flash chromatography column contains between 10 mg to 1 kg of the semi-spherical and porous silica gel.
18. The pre-filled flash chromatography column according to claim 16 adapted to purify synthetic products in quantities comprised between 10 mg to 100 g.