Disialoundecasaccharide chain asparagine/fatty acid amide and medical drug containing the same
An asparagine-linked disialoundecaoligosaccharide-fatty acid amide, a drug containing the same, and a drug containing an asparagine-linked disialoundecaoligosaccharide.
1. An asparagine-linked disialoundecaoligosaccharide-fatty acid amide which does not have an amino acid other than the asparagine, wherein the disialoundecaoligosaccharide has the formula:
and wherein the fatty acid is one having 8 to 24 carbon atoms.
2. An asparagine-linked disialoundecaoligosaccharide-fatty acid amide according to claim 1 wherein the fatty acid is one having 10 to 22 carbon atoms.
3. An asparagine-linked disialoundecaoligosaccharide-fatty acid amide according to claim 2 wherein the fatty acid is at least one selected from the group consisting of capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, arachic acid, behenic acid and oleic acid.
4. A composition comprising asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 1 and a pharmaceutical additive.
5. A composition according to claim 4 wherein the pharmaceutical additive is at least one selected from the group consisting of lactose, glycerin, glucose, sucrose and mannitol.
6. A drug containing the asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 1 .
7. A drug comprising at least one selected from asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 1 and asparagine-linked disialoundecaoligosaccharide having formula 3:
and a pharmaceutical additive.
8. A composition comprising asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 2 , and a pharmaceutical additive.
9. A composition comprising asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 3 , and a pharmaceutical additive.
10. A composition according to claim 8 wherein the pharmaceutical additive is at least one selected from the group consisting of lactose, glycerin, glucose, sucrose and mannitol.
11. A composition according to claim 9 wherein the pharmaceutical additive is at least one selected from the group consisting of lactose, glycerin, glucose, sucrose and mannitol.
12. A method of treating influenza comprising administering a therapeutically effectively amount of an asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 1 to a subject in need of such treatment.
13. A method of treating influenza comprising administering a therapeutically effective amount of an asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 2 to a subject in need of such treatment.
14. A method of treating influenza comprising administering a therapeutically effective amount of an asparagine-linked disialoundecaoligosaccharide-fatty acid amide of claim 3 to a subject in need of such treatment.
15. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 4 to a subject in need of such treatment.
16. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 5 to a subject in need of such treatment.
17. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 8 to a subject in need of such treatment.
18. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 9 to a subject in need of such treatment.
19. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 10 to a subject in need of such treatment.
20. A method of treating influenza comprising administering a therapeutically effective amount of a composition of claim 11 to a subject in need of such treatment.
21. A method of treating influenza comprising administering a therapeutically effective amount of a drug of claim 6 to a subject in need of such treatment.
22. A method of treating influenza comprising administering a therapeutically effective amount of a drug of claim 7 to a subject in need of such treatment.