IP Library › Granted Patent US 7,612,880
Granted Patent B2
US 7,612,880 · App. 10/567,104 · Granted Nov 3, 2009

Advanced polarization imaging method, apparatus, and computer program product for retinal imaging, liquid crystal testing, active remote sensing, and other applications

Assignee: Arizona Board of Regents on Behalf of the University of Arizona
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Quick Facts
Patent No.
US 7,612,880
App. No.
10/567,104
Granted
Nov 3, 2009
Kind
B2
Abstract

A method, apparatus, and computer program product for identifying features in a sample by analyzing Mueller matrices to calculate an average degree of polarization, a weighted average degree of polarization, a degree of polarization map, a degree of polarization surface. Also, a method, apparatus, and computer program product for identifying features in a sample by analyzing Mueller matrices to calculate depolarization relative to a retardance axis and/or a diattentuation axis, and to calculate a ratio of diattenuation to polarizance or ratios of row and column magnitudes. Also, a method for retinal polarimetry, including a non-depolarizing light tube configured for insertion into the eye.

Claims (52)

1. A method for identifying features in an object, comprising:

positioning and focusing a polarimeter onto the object;

illuminating the object with a series of at least 16 polarization states;

analyzing a plurality of reflected images corresponding to said at least 16 polarization states;

obtaining a Mueller matrix from the plurality of reflected images; and

calculating a plurality of depolarization parameters, except for the depolarization index, from the Mueller matrix as a contrast mechanism for identifying features of the illuminated object.

2. The method of claim 1 , wherein said depolarization parameters comprise:

at least one of an average degree of polarization or a weighted average degree of polarization of the illuminated object.

3. The method of claim 1 , wherein said depolarization parameters comprise:

at least one of a degree of polarization surface or a degree of polarization map of the reflected images.

4. The method of claim 1 , further comprising:

calculating at least one of a minimum and a maximum degrees of polarization of the reflected images.

5. The method of claim 4 , wherein said step of calculating at least one of a minimum and a maximum degrees of polarization comprises:

calculating both a minimum and a maximum degrees of polarization; and

calculating a difference between said minimum and a maximum degrees of polarization.

6. The method of claim 1 , further comprising:

decomposing said Mueller matrix into a depolarization matrix and at least one of a diattentuation matrix and a retardance matrix.

7. The method of claim 6 , further comprising:

calculating a depolarization relative to a corresponding diattentuation or retardance axis.

8. The method of claim 6 , further comprising:

calculating a depolarization relative to a corresponding diattentuation or retardance off-axis.

9. The method of claim 1 , further comprising: calculating a ratio of diattenuation to polarizance.

10. The method of claim 1 , further comprising:

calculating a ratio of an average magnitude of Mueller matrix rows to an average magnitude of Mueller matrix columns.

11. The method according to any one of claims 1 - 8 or 9 - 10 , wherein said polarimeter comprises at least one of an optical polarimeter, an X-ray polarimeter, an IR polarimeter, or a UV polarimeter.

12. A method of retinal polarimetry, comprising:

emitting laser light to a retina via (a) a polarizer, (b) a first liquid crystal polarization controller, (c) a non-polarizing beam splitter, (d) a rotating half-wave retarder, and (e) an objective lens, the laser light passing through (a), (b) and (c) in this order;

reflecting light from the retina to a co-polarized photodetector via the objective lens to generate reflected images, the rotating half-wave retarder, the non-polarizing beam splitter, a second liquid crystal polarization controller, and a polarizing beam splitter;

obtaining a Mueller matrix from the plurality of reflected images; and

calculating a plurality of depolarization parameters, except for the depolarization index, from the Mueller matrix as a contrast mechanism for identifying features of the illuminated retina.

13. The method of claim 12 , further comprising:

passing light from said polarizing beam splitter to a cross-polarized photodetector.

14. The method of claim 13 , further comprising:

adjusting a light parameter by controlling the retardance of said first and second liquid crystal polarization controllers by changing a respective retardance over more than one wave of retardation.

15. The method of claim 14 , further comprising:

acquiring four sets of images, wherein

a first set of images corresponds to the two liquid crystal polarization controllers being adjusted to +7/8 and +7/8 waves retardance,

a second set of images corresponds to the two liquid crystal polarization controllers being adjusted to +7/8 and +9/8 waves retardance,

a third set of images corresponds to the two liquid crystal polarization controllers being adjusted to +9/8 and +9/8 waves, and

a fourth set of images corresponds to the two liquid crystal polarization controllers being adjusted to +9/8 and +7/8 waves.

16. A method of retinal polarimetry, comprising:

illuminating a retina with polarized light via a probe inserted into the eye;

producing a depolarization parameter and one of a retardance and a diattenuation parameter;

collecting light reflected off the retina with a receiver located outside of the eye or inside of the eye;

analyzing the reflected light with a polarization state analyzer;

obtaining a Mueller matrix image from the reflected light; and

analyzing said Mueller matrix by calculating a plurality of depolarization parameters, except for the depolarization index, from the Mueller matrix as a contrast mechanism for use in identifying features of the retina.

17. The method of claim 2 , further comprising:

generating a polarization image with at least one of the average degree of polarization or the weighted average degree of polarization of the reflected images to detect a structure in the illuminated object.

18. The method of claim 16 , further comprising:

generating a polarization image with at least one of an average degree of polarization or a weighted average degree of polarization of the reflected light to detect a structure in the retina.

19. The method of claim 11 , wherein the polarimeter is a retinal polarimeter.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 30, 2007
From: CHIPMAN, RUSSELL
To: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
Reel/Frame 019620/0354 →
Continuity (2)
Provisional Application 6049280500 · Aug 6, 2003
Related Publication 20070146632A1 · Jun 28, 2007