Device and method for applying active substances to the surface of a wound

1 - 12 . (canceled)

13 . A device for application of active substances onto a wound surface, the device comprising:

an inlay of a porous material for laying upon the wound surface,

a sealing overlay for covering the wound surface and the inlay, which overlay is sealingly secured to the skin surface,

at least one supply line for a liquid active substance leading into the inlay, which supply line includes a controllable shut-off valve,

at least one drainage line leading from the inlay, which drainage line is connectible to a source of partial vacuum and which drainage line includes a controllable shut-off valve, and

a controller configured to control the shut-off valves such that the shut-off valve of the supply line and the shut-off valve of the drainage line are not simultaneously overlappingly opened and such that an active time interval is established in between the closures of the shut-off valve of the drainage line,

wherein the liquid active substance contains bacteriophages.

14 . A device according to claim 13 , wherein the bacteriophages are lytic bacteriophages.

15 . A device according to claim 13 , wherein the inlay is comprised of an elastic compressible porous material.

16 . A device according to claim 15 , wherein the inlay is comprised of an open-pore foam material.

17 . A device according to claim 13 , wherein the controller determines, following drainage or suctioning, a partial-vacuum time interval in which a predetermined partial-vacuum is maintained in the inlay.

18 . A device according to claim 13 , wherein at least one sensor is introduceable under the sealing overlay, which sensor is operatively connected to the controller and measures at least one of the bacteriophage concentration, the pH value, and the temperature.

19 . A device according to claim 13 , wherein at least one of the bacteriophage concentration, the pH value, and the temperature of the liquid active agent is adjustable.

20 . A process for application of active substances to a wound surface, said process comprising:

providing an inlay of a porous material covering in two dimensions upon the wound surface and the inlay

providing a sealing overlay covering over and sealing the inlay around the edges of the wound,

introducing at least one liquid active substance via at least one supply line into the porous inlay

suctioning the liquid active substance out of the inlay via at least one drainage line,

wherein the introduction and the suctioning of the active substance is time-wise controlled to be in separate time intervals (T 1 or as the case may be T 3 ),

wherein between the introduction and the suctioning an active time interval T 3 is established, and

wherein the liquid active substance contains bacteriophages.

21 . A process according to claim 20 , wherein the bacteriophages are lytic bacteriophages.

22 . A process according to claim 20 , wherein subsequent to the suctioning (T 3 ) of the active substance until the next introduction (T 1 ) a vacuum time interval (T 4 ) is established, in which a partial vacuum is maintained under the covering overlay.

23 . A process according to claim 20 , wherein at least one of the bacteriophage concentration, the pH value and the temperature of the introduced active substance is controlled.

24 . A process according to claim 23 , wherein at least one of the phage concentration, the pH value and the temperature is measured at the wound surface and used for controlling the introduction of the active substance.