Granted Patent
B2
US 7,652,043 · App. 10/574,248 · Granted Jan 26, 2010
WNT pathway antagonists
Assignee:
The Johns Hopkins University
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Abstract
Aromatic compounds for treating various diseases and pathologies are disclosed. The methods use of such compounds are also provided. Accordingly, the present invention makes available methods and compositions for inhibiting aberrant growth states in cells having Wnt receptors.
Claims (4)
1. A compound having structure (I):
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising the compound of claim 1 , in a pharmaceutical acceptable carrier.
3. A process for making a pharmaceutical composition comprising the compound of claim 1 , or its pharmaceutically acceptable salts, crystal forms salts and individual diastereomers thereof, and a pharmaceutically acceptable carrier.
Assignments (2)
CONFIRMATORY LICENSE
Recorded Nov 28, 2017
From: JOHNS HOPKINS UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 044824/0374 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 20, 2006
From: BEACHY, PAUL A.; CHEN, JAMES K.; MANN, RANDALL K.
To: THE JOHNS HOPKINS UNIVERSITY
Reel/Frame 017819/0297 →
Continuity (2)
Provisional Application
6050716300
· Sep 29, 2003