Therapeutic applications for C-peptide
The present invention relates to administration of C-peptide in a once daily dose for use in the treatment of diabetes and diabetic complications.
1. A method of treating diabetes and/or microvascular diabetic complications comprising administering C-peptide or a pharmaceutical composition comprising C-peptide to a patient once daily wherein said once daily administration does not include a continuous administration or the presence of release rate-controlling agents, wherein said administration is by subcutaneous administration, and wherein said pharmaceutical composition contains 100 to 1800 nmol of C-peptide.
2. The method according to claim 1 , wherein said C-peptide is human C-peptide.
3. The method according to claim 1 , wherein said C-peptide is a fragment EGSLQ (SEQ ID NO: 2).
4. The method according to claim 1 , wherein said patient is a human.
5. The method according to claim 1 , wherein said C-peptide is in an aqueous solution.
6. The method according to claim 1 , wherein said complications are diabetic nephropathy, retinopathy or neuropathy.
7. The method according to claim 6 , wherein said complications are diabetic neuropathy.