IP Library Granted Patent US 7,208,089
Granted Patent B2
US 7,208,089 · App. 10/627,967 · Granted Apr 24, 2007

Biomimetic membranes

Assignee: MT Technologies, Inc.
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Quick Facts
Patent No.
US 7,208,089
App. No.
10/627,967
Granted
Apr 24, 2007
Kind
B2
Abstract

Biological membrane proteins are incorporated into a co-polymer matrix to produce membranes with a wide variety of functionalities. In one form of the invention, a composite membrane incorporates two different proteins which cooperate to produce electricity from light. In another form, water transport proteins are embedded in a membrane to enable water purification.

Claims (32)

1. A biomimetic membrane, comprising:

a tri-block copolymer matrix simulating a natural biological membrane and natural protein environment; and

membrane proteins incorporated into said matrix to form a membrane/protein composite.

2. The membrane of claim 1 , wherein the membrane/protein composite composes a device which has the function of the incorporated membrane proteins.

3. The membrane of claim 2 , wherein the protein functions include valves, channels, sensors, detectors, pumps, and energy transducers.

4. The membrane of claim 1 , wherein said membrane proteins are selected to transport only water molecules, whereby said biomimetic membrane is a water filter.

5. The membrane of claim 4 , wherein said membrane proteins are selected from the aquaporin family of proteins.

6. The membrane of claim 5 , wherein said matrix is impermeable to water, and wherein said membrane proteins are selected to permit passage of water molecules under pressure.

7. The membrane of claim 6 , wherein said matrix is supported in a water purification device to separate said device into first and second chambers, said membrane proteins permitting only water to flow between said chambers.

8. The membrane of claim 1 , wherein said membrane proteins are genetically engineered proteins.

9. The membrane of claim 8 , wherein two different membrane proteins are incorporated into said matrix.

10. The membrane of claim 9 , wherein said membrane proteins are energy converting proteins.

11. The membrane of claim 1 , wherein said matrix is incorporated in a thin fabric.

12. The membrane of claim 11 , wherein said membrane proteins include bacteriorodopsin and cytochrome oxydase embedded in said matrix for converting optical energy to electrical energy.

13. The membrane of claim 12 , further including first and second electrodes on opposite surfaces of said fabric for receiving said electrical energy.

14. The membrane of claim 1 , wherein said matrix receives oriented bacteriorodopsin and cytochrome oxidase to produce a biosolar cell.

15. The membrane of claim 14 , further including electrodes on opposite sides of said matrix.

16. The membrane of claim 14 , wherein said matrix is a biocompatible polymer impermeable to protons.

17. A hybrid organic/inorganic power source, comprising:

a tri-block copolymer matrix; and

first and second different membrane proteins embedded in said matrix.

18. The power source of claim 17 , further including a thin fabric material, said matrix being embedded in said fabric.

19. The power source of claim 18 , wherein said membrane proteins are natural biological proteins.

20. The power source of claim 19 , wherein said proteins comprise bacteriorodopsin and cytochrome oxidase for converting light energy into electrical energy.

21. The power source of claim 20 , further including electrodes on opposed surfaces of said fabric for receiving said electrical energy.

22. A method of fabricating a biological membrane, comprising:

fabricating a tri-block copolymer matrix; and

inserting in said matrix natural or genetically engineered membrane proteins.

23. The method of claim 22 , further including orienting said membrane proteins in said matrix.

24. The method of claim 22 , further including selecting said proteins to produce a corresponding membrane functionality.

25. The method of claim 22 , further including inserting in said matrix two different membrane proteins.

26. The method of claim 25 , further including exposing said matrix to light to produce electrical energy across said matrix.

Assignments (6)
CORRECTIVE ASSIGNMENT TO REMOVE INCORRECT SERIAL NO. 61/013,281 PREVIOUSLY RECORDED AT REEL: 031772 FRAME: 0514. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Jul 30, 2014
From: AQUAZ A/S
To: APPLIED BIOMIMETIC A/S
Reel/Frame 033452/0851 →
CHANGE OF NAME Recorded Dec 8, 2013
From: AQUAZ A/S
To: APPLIED BIOMIMETIC A/S
Reel/Frame 031772/0514 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2011
From: MT TECHNOLOGIES
To: DANFOSS AQUAZ A/S
Reel/Frame 025691/0199 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 25, 2011
From: MT TECHNOLOGIES, INC.
To: DANFOSS AQUAZ A/S
Reel/Frame 025691/0239 →
CHANGE OF NAME Recorded Jan 25, 2011
From: DANFOSS AQUAZ A/S
To: AQUAZ A/S
Reel/Frame 025691/0418 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 6, 2003
From: MONTEMAGNO, CARLO D.; SCHMIDT, JACOB J.; TOZZI, STEVEN P.
To: MT TECHNOLOGIES, INC.
Reel/Frame 014667/0894 →
Continuity (3)
Provisional Application 6043878400 · Jan 9, 2003
Provisional Application 6039878400 · Jul 29, 2002
Related Publication 20040049230A1 · Mar 11, 2004