Low disturbance pulsatile flow system
A flow system device used for testing/creating fluid flow. The system comprises at least one fluid filled loop and a rotor stage for maintaining at least one rotor. The loop is positioned on the rotor. The device also includes a driving motor for rotating the rotor stage and a motion controller for controlling the speed and directional motion of the motor.
1. A flow system device used for creating, monitoring, and controlling specific modifiable fluid flow patterns, said system comprising:
at least one fluid filled loop;
a rotor stage for maintaining at least one rotor, said loop positioned on said rotor;
a driving motor for rotating said rotor stage;
a motion controller for controlling the speed and directional motion of said motor;
an external measurement system to observe, record, and control the contained loop flow within said at least one loop.
2. The flow system device of claim 1 wherein a vascular prosthesis is placed within the tube.
3. The flow system device of claim 2 , wherein said vascular prosthesis is a stent or graft.
4. The flow system device of claim 2 wherein the stents are coated with gold or stainless steel.
5. The flow system device of claim 1 wherein the created fluid flow is bidirectional.
6. The flow system device of claim 5 wherein the specific fluid flow pattern produced and observed is that of coronary flow.
7. The flow system device of claim 1 wherein the loop includes a one way valve.
8. The flow system device of claim 1 wherein the system included six rotors with six corresponding fluid filled loops.
9. The flow system device of claim 1 wherein the fluid is blood.
10. The flow system of claim 1 wherein a biological signal is created.
11. The flow system device of claim 10 wherein the biological signal is a thrombotic signal.
12. The flow system device of claim 10 wherein the fluid flow within the loop is controllable, such that flow dependent variations in the biological signal are generated.
13. The flow system device of claim 1 wherein the fluid flow within the loop is controllable such that the effects of background noise is minimized.
14. The flow system device of claim 1 wherein the loop has the geometric characteristics of a coronary arterial segment.
15. A method of creating, monitoring, and controlling specific, modifiable fluid flow patterns, said method comprises:
providing a fluid flow system including at least one loop, a rotor stage for maintaining at least one rotor, the loop position on the rotor, a driving motor for rotating the rotor stage, a motion controller for controlling the speed and directional motion of the rotor, and an external measurement system to observe, record, and control the contained loop flow;
filling the at least one loop with fluid which is to be tested;
controlling the motor to obtain the desired motion of the fluid within the tube;
measuring the desired effects of the fluid flow.
16. The method of claim 15 wherein the fluid is blood.
17. The method of claim 15 wherein a vascular prosthesis is maintained within the tube.
18. The method of claim 17 wherein the vascular prosthesis is a stent or graft.
19. The method of claim 17 wherein the biologic effect of the vascular prosthesis on the blood is measured.
20. The method of claim 19 wherein the loop has the geometric characteristics of a coronary arterial segment.
21. The method of claim 19 wherein the specific fluid flow pattern produced and observed is that of coronary flow.
22. The method of claim 19 wherein the biological effect is a thrombotic effect.
23. The method of claim 15 wherein the fluid flow within the loop is controlled, such that flow-dependent variations in the desired, measured effects are generated.