IP Library Granted Patent US 6,906,516
Granted Patent B2
US 6,906,516 · App. 10/635,672 · Granted Jun 14, 2005

Artifact reduction in SSFP MRI using weighted sum of combined signals

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 6,906,516
App. No.
10/635,672
Granted
Jun 14, 2005
Kind
B2
Abstract

Artifact reduction in steady state free precession magnetic resonance imaging uses weighting of acquired image data to emphasize higher signals and then establishing an image signal based on the combined weighted signals. In one embodiment, a SSFP imaging sequence uses phase cycling and acquired image data is squared with the squared data then combined. The final image signal is based on the square root of the squared data.

Claims (45)

1. A method of reducing artifacts in steady state free precession (SSFP) signals for use in magnetic resonance imaging comprising the steps of:

a) applying a plurality of SSFP imaging sequences to an object to be imaged,

b) acquiring image data for each of the SSFP imaging sequences,

c) weighting the image data to emphasize higher magnitude signals,

d) combining the weighted image data from all imaging sequences, and

e) establishing an image signal based on the combined weighted image data.

2. The method as defined by claim 1 wherein the plurality of SSFP imaging sequences are phase-cycled.

3. A method of reducing artifacts in steady state free precession (SSFP) signals for use in magnetic resonance imaging comprising the steps of:

a) applying a plurality phase-cycled of SSFP imaging sequences to an object to be imaged,

b) acquiring image data for each of the SSFP imaging sequences,

c) weighting by squaring the image data for each sequence to emphasize higher signals,

d) combining by summing the weighted image data, and

e) establishing an image signal based on the combined weighted image data.

4. The method as defined by claim 3 wherein step e) establishes an image signal from the square root of the sum of the squares of the image data.

5. A method of reducing artifacts in steady state free precession (SSFP) signals for use in magnetic resonance imaging comprising the steps of:

a) applying a plurality of phase-cycled of SSFP imaging sequences to an object to be imaged,

b) acquiring image data for each of the SSFP imaging sequences,

c) weighting the image data to emphasize higher signals based on a computed off-resonance profile using a magnetic field map for the imaged object,

d) combining the weighted image data, and

e) establishing an image signal based on the combined weighted image data.

6. A method of reducing artifacts in steady state free precession (SSFP) signals for use in magnetic resonance imaging comprising the steps of:

a) applying a plurality phase-cycled of SSFP imaging sequences to an object to be imaged,

b) acquiring image data for each of the SSFP imaging sequences wherein N phase-cycled individual SSFP image acquisitions are performed with the n th acquisition incrementing the phase from excitation to excitation by

Δφ=2πn/N 2

c) weighting the image data to emphasize higher signals,

d) combining the weighted image data, and

e) establishing an image signal based on the combined weighted image data.

7. The method as defined by claim 6 wherein step c) squares the image data for each sequence, and step d) sums the squares of the image data.

8. The method as defined claim 7 wherein step e) establishes an image signal from the square root of the sum of the squares of the image data.

9. The method as defined by claim 8 wherein the SSFP image data is two-dimensional.

10. The method as defined by claim 8 wherein the SSFP image data is three-dimensional.

11. A method of reducing artifacts in steady state free precession (SSFP) signals for use in magnetic resonance imaging comprising the steps of:

a) applying a plurality of SSFP imaging sequences to an object to be imaged, wherein each SSFP imaging sequence includes:

i) placing a body in a magnetic field,

ii) applying gradient magnetic fields to the body,

iii) applying a plurality of RE excitation pulses to the body at repetition time, TR, to flip nuclei spins, with RF phase incremental from TR to TR by a phase increment, Δφ

iv) rewinding all gradients over each repetition time, TR,

v) measuring refocused MRI signals at echo times, TE during each sequence, and

vi) repeating steps ii-v) for subsequent sequences with the RE excitation pulses in each sequence being incremented in phase by a different Δφ,

b) acquiring image data for each of the SSFP imaging sequences,

c) weighting the image data to emphasize higher signals,

d) combining the weighted image data, and

e) establishing an image signal based on the combined weighted image data.

12. The method as defined by claim 11 wherein the SSFP image data is three-dimensional.

13. The method as defined by claim 11 wherein the SSFP image data is two-dimensional.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jul 28, 2010
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024753/0450 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 4, 2003
From: BANGERTER, NEAL K.; NISHIMURA, DWIGHT G.
To: BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE
Reel/Frame 014386/0552 →
Continuity (1)
Related Publication 20050030023A1 · Feb 10, 2005