Vasoocclusive coil with enhanced therapeutic strand structure
A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature. The stretch resistant member may be formed from a therapeutic and/or bioactive non-metallic material to enhance the therapeutic properties of the vasoocclusive coil.
1. An apparatus for release and deployment of a stretch resistant therapeutic device within a patient's vasculature, comprising:
a vasoocclusive coil having a proximal end and a distal end, said vasoocclusive coil defining a lumen between said proximal and distal ends;
an elongated pusher member having a distal end adjacent to said proximal end of said vasoocclusive coil;
at least one loop of fiber material attached to said elongated pusher member, said at least one loop of fiber material being severable by heating of said at least one loop of fiber material;
a loop attached to the proximal end of said coil and detachably mounted to said at least one loop of fiber material attached to the pusher member;
an electrical resistance heater wire disposed adjacent to said at least one loop of fiber material, said electrical resistance wire being connected to a control unit for heating and thereby severing said at least one loop of fiber material; and
a stretch resistant member extending through said lumen of said vasoocclusive coil, said stretch resistant member having first and second ends, said stretch resistant member being formed of a therapeutic non-metallic fiber material, and said stretch resistant member being doubled and said stretch resistant member being fixedly attached to said vasoocclusive coil only at said distal end of said vasoocclusive coil forming a loop and said loop being detachably mounted to the distal end of the elongated pusher member by said at least one loop of fiber material to allow for placement of the vasoocclusive coil within the patient's vasculature.
2. The apparatus of claim 1 , wherein said stretch resistant member is formed of a ribbon.
3. The apparatus of claim 1 , wherein said stretch resistant member is formed of a braid.
4. The apparatus of claim 1 , wherein said stretch resistant member is formed of a primary wind.
5. The apparatus of claim 1 , wherein said stretch resistant member is formed of a stranded material.
6. The apparatus of claim 1 , wherein said stretch resistant member is formed of a multi-filament material.
7. The apparatus of claim 1 , wherein said stretch resistant member is formed of a twisted multi-filament material.
8. The apparatus of claim 1 , wherein said therapeutic non-metallic fiber material is selected from the group consisting of silk, collagen, elastin, polyglycolic acid, polylactic acid, poly(D,L-lactic acid-co-glycolic acid), poly(L-lactide), poly(L-lactide-co-D,L-lactide), poly(L-lactide-co-glycolide), poly(glycolide-co-trimethylene carbonate), polyethylene oxide, polydioxanone, polycaprolactone, hylauric acid, polyhydroxylbutyrate, poly(phosphazene), poly(D,L-lactide-co-caprolactone), poly(glycolide-co-caprolactone), polyvinyl alcohol, polyanhydrides thereof, poly(ortho esters) thereof, poly(phoshate esters) thereof, poly(amino acids) thereof, poly(hydroxy butyrates) thereof, copolymers thereof, composites thereof, and combinations thereof.
9. The apparatus of claim 8 , wherein said therapeutic non-metallic fiber material is a bioactive material.
10. The apparatus of claim 8 , wherein said therapeutic non-metallic fiber material is bioabsorbable.
11. The apparatus of claim 8 , wherein said therapeutic non-metallic fiber material is non-absorbable.
12. The apparatus of claim 8 , wherein a therapeutic agent is absorbed by said therapeutic non-metallic fiber material.
13. The apparatus of claim 1 , wherein said therapeutic non-metallic fiber material is formed from a polymer selected from the group consisting of an ethylene-octene copolymer, polypropylene, polyethylene, polyacrylate, polyacrylamide, poly(hydroxyethyl methacrylate), polyurethane, polysiloxane, and copolymers thereof.
14. The apparatus of claim 8 or 13 , wherein the vasoocelusive coil is attached to the first and second ends of the stretch resistant member by heating of the first and second ends of the fiber.
15. The apparatus of claim 1 , wherein said stretch resistant member is radiopaque.
16. The apparatus of claim 1 , wherein said at least one loop of fiber material is formed from a thermoplastic material.
17. The apparatus of claim 1 , wherein said at least one loop of fiber material is formed from polyethylene.