IP Library Granted Patent US 6,947,781
Granted Patent B2
US 6,947,781 · App. 10/734,732 · Granted Sep 20, 2005

Vibratory venous and arterial oximetry sensor

Assignee: Massachusetts Institute of Technology
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Quick Facts
Patent No.
US 6,947,781
App. No.
10/734,732
Granted
Sep 20, 2005
Kind
B2
Abstract

A method and an apparatus for distinguishing concentrations of blood constituents among distinct vascular components in situ. The method has steps of inducing periodic vibration, characterized by a frequency, in a limb of a person in such as manner as to selectively excite a resonant response in a specified blood vessel of the person, an artery or a vein, illuminating the limb of the person with a light source, and synchronously detecting a plethysmographic signal for discriminating response attributable to the specified blood vessel.

Claims (17)

1. A method for distinguishing concentrations of blood constituents among distinct vascular components in situ, the method comprising:

a. inducing periodic vibration, characterized by a frequency, in a limb of a person in such a manner as to selectively excite a resonant response in a specified blood vessel of the person;

b. illuminating the limb of the person with a light source;

c. detecting light from the light source that has traversed the specified blood vessel and generating a plethysmographic signal corresponding thereto; and

d. synchronously detecting the plethysmographic signal for a discriminating response attributable to the specified blood vessel.

2. A method in accordance with claim 1 , wherein the specified blood vessel is a vein.

3. A method in accordance with claim 1 , further including the step of separately monitoring the plethysmographic signal attributable to the specified blood vessel and a plethysmographic signal attributable to a second specified blood vessel.

4. A method in accordance with either of claim 1 or 3 , wherein the step of illuminating the limb includes illuminating with two wavelengths of light.

5. A method in accordance with claim 4 , further including the step of ratioing light detected at each of the two wavelengths of light in order to derive oxygen saturation of blood in the vein.

6. A method in accordance with claim 1 , wherein the step of inducing vibration in the limb includes modulating air pressure applied to at least one inflatable pad enveloping the limb at least in part.

7. An apparatus for inducing a plethysmographic response due to blood in a specified blood vessel of a person, the apparatus comprising:

a. a vibrator for inducing periodic vibration, characterized by a frequency, in a limb of a person in such a manner a to selectively excite a resonant response in the specified blood vessel of the person;

b. a light source for illuminating the limb of the person;

c. a detector for detecting light from the light source that has traversed the specified blood vessel and for generating a plethysmographic signal corresponding thereto; and

d. a signal processor for synchronously detecting the plethysmographic signal and for a discriminating response attributable to the specified blood vessel.

8. An apparatus in accordance with claim 7 , wherein the vibrator is a mechanical perturber.

9. An apparatus in accordance with claim 7 , wherein the vibrator is a fluidic perturber.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 10, 2020
From: FENG, SIMIN; BOULAIS, KEVIN A.; SESSIONS, WALTER D.; RAYMS-KELLER, PEARL; NICHOLS, ROBERT B.; SMITH, WILLIAM F.; LONG, KAREN J.; LOWRY, MICHAEL S.
To: UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
Reel/Frame 055041/0687 →
CONFIRMATORY LICENSE Recorded May 5, 2011
From: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 026223/0338 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2004
From: ASADA, HARUHIKO H.; SHALTIS, PHILLIP
To: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Reel/Frame 014862/0623 →
Continuity (2)
Provisional Application 6043357000 · Dec 13, 2002
Related Publication 20040230107A1 · Nov 18, 2004