Method for treatment of tumors using nordihydroguaiaretic acid derivatives
Use of nordihydroguaiaretic derivatives to suppress CDC-2 and survivin, stimulate apoptosis, and treat tumors.
1. A method for treating leukemia, said method consisting essentially of the steps of:
(a) providing a composition consisting essentially of an effective amount of tetra-O-methyl nordihydroguaiaretic acid;
and optionally one or more pharmaceutically acceptable excipients or carriers;
(b) administering the composition to an individual in need of treatment; and
(c) wherein the leukemia treatment consists essentially of administration of said composition for the length of a treatment regimen.
2. The method of claim 1 wherein the individual is a mammal.
3. The method of claim 2 , wherein said mammal is a human.
4. The method of claim 1 , wherein said tetra-O-methyl nordihydromaiaretic acid is administered with at least one pharmaceutically acceptable excipient or carrier.
5. The method of claim 4 , wherein said excipient or carrier is dimethylsulfoxide.