Nematode PAN and ZP receptor-like sequences
Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
1. A purified polypeptide comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of SEQ ID NO: 11.
2. The purified polypeptide of claim 1 , wherein the amino acid sequence is at least 90% identical to the amino acid sequence of SEQ ID NO: 11.
3. The purified polypeptide of claim 2 , wherein the amino acid sequence is at least 95% identical to the amino acid sequence of SEQ ID NO: 11.
4. A purified polypeptide comprising the amino acid sequence of SEQ ID NO: 11.