Pyrazolopyrimidines as cyclin dependent kinase inhibitors
View Patent ↗In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
1. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
2. A compound of claim 1 in purified form.
3. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
4. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
5. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
6. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
7. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
8. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
9. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
10. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
11. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
12. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
13. A compound of the formula:
or a pharmaceutically acceptable salt thereof.