Patent Assignment
Reel/Frame 061102/0145
Merger
Recorded: 2022-08-08
Pages: 60
Assignor
MERCK SHARP & DOHME CORP.
Executed: 2022-04-07
Assignee
MERCK SHARP & DOHME LLC
126 EAST LINCOLN AVENUE, RAHWAY, NEW JERSEY, 07065
Covered Properties
(2014)
Clinical Trial Management System
Patent:
7,054,823 →
Application:
09/655,667 →
Estrogen Receptor Modulators
Novel Peptides as NS3-Serine Protease Inhibitors of Hepatitis C Virus
Mammalian Cytokines; Receptors; Related Reagents and Methods
Nucleoside Derivatives as Inhibitors of Rna-Dependent Rna Viral Polymerase
Use of Substituted Azetidinone Compounds for the Treatment of Sitosterolemia
N-Substituted Nonaryl-Heterocyclic Nmda/NR2B Antagonists
Microarray Reaction Cartridge
Patent:
7,294,478 →
Application:
10/092,285 →
Methods for the Treatment or Inhibition of Ileus
Beta-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Novel Processes for the Preparation of Peripheral Opioid Antagonist Compounds and Intermediates Thereto
Nucleoside Derivatives as Inhibitors of Rna-Dependent Rna Viral Polymerase
Adenosine A2A Receptor Antagonists
Ribavirin Syrup Formulations
Ectocornea Extension Promoters
Adenosine A2A Receptor Antagonists
Adenosine A2A Receptor Antagonists
[1,2,4]-Triazole Bicyclic Adenosine A2A Receptor Antagonists
Pharmaceutical Composition of a Tachykinin Receptor Antagonist
Process for Making Spirolactone Compounds
N-Biphenyl(Substituted Methyl) Aminocycloalkane-Carboxamide Derivatives
Pharmaceutical Formulations of Antineoplastic Agents and Processes of Making and Using the Same
Substituted Amides
Human Monoclonal Antibodies to Interleukin-5
Tetrahydropyranyl Cyclopentyl Tetrahydropyridopyridine Modulators of Chemokine Receptor Activity
Codon-Optimized B-Secretase and Methods of Refolding and Processing
Patent:
7,166,454 →
Application:
10/443,949 →
11-Beta-Hydroxysteroid Dehydrogenase 1 Inhibitors Useful for the Treatment of Diabetes, Obesity and Dyslipidemia
Phenylalanine Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Beta-Amino Tetrahydroimidazo (1, 2-a) Pyrazines and Tetrahydrotrioazolo (4,3-a) Pyrazines as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Process for Making Carbapenem Compounds
Benzimisazo[4,5-F]Isoquinolinone Derivatives
Interactive Product Selection System
Heteroaryl Substituted Tetrazole Modulators of Metabotrophic Glutamate Receptor-5
Hepatitis C Virus Vaccine
Heteroaryl Substituted Pyrazole Modulators of Metabotropic Glutamate Receptor-5
N-Biphenylmethyl Aminocycloalkanecarboxamide Derivatives
Pharmaceutical Treatment Blister Card
Di-Aryl Substituted Tetrazole Modulators of Metabotropic Glutamate Receptor-5
Aminoalkylphenols, Methods of Using and Making the Same
Process for 5-[[2(R)-[1(R)-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3(S)-(4-Fluorophenyl)-4-Morpholinyl]Methyl]-1,2-Dihydro-3H-1,2,4-Triazol-3-One
Methods of Adenovirus Purification
Computer Systems and Methods for Subdividing a Complex Disease into Component Diseases
Piperidino Pyrimidine Dipeptidyl Peptidase Inhibitors for the Treatment of Diabetes
Tiacumicin Production
Tyrosine Kinase Inhibitors
Indoles Having Anti-Diabetic Activity
Estrogen Receptor Modulators
Beta-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors for Diabetes
Phenylcarboxamide Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Phenylalanine Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Method of Treating a Malignancy in a Subject via Direct Picornaviral-Mediated Oncolysis
Computer systems and methods for associating genes with traits using cross species data
Macrocyclic Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
3-Amino-4-Phenylbutanoic Acid Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
3-Amino-4-Phenylbutanoic Acid Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Substituted Pyrazoles, Compositions Containing Such Compounds and Methods of Use
Carboxamide Spirohydantoin Cgrp Receptor Antagonists
Monocyclic Anilide Spirohydantoin Cgrp Receptor Antagonists
Aryl Spirohydantoin Cgrp Receptor Antagonists
Benodiazepine Spirohydantoin Cgrp Receptor Antagonists
Bicyclic Anilide Spirohydantoin Cgrp Receptor Antagonists
Process for the Preparation of Chiral Beta Amino Acid Derivatives by Asymmetric Hydrogenation
Optimized Expression of HPV31 L1 in Yeast
Cgrp Receptor Antagonists
Androgen Receptor Modulators and Methods of Use Thereof
Benzamidazoles, Compositions Containing Such Compounds and Methods of Use
3-Amino-4-Phenylbutanoic Acid Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Methods and compositions for rna interference
Triazole Derivatives as Inhibitors of 11-Beta Hydroxysteroid Dehydrogenase-1
Computer Systems and Methods for Identifying Surrogate Markers
Fused Indoles as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
3-Fluoro-Piperidines as Nmda/NR2B Antagonists
Antibiotic Compounds
Cyclohexylglycine Derivatives as Dipeptidyl Peptidase Inhibitors for the Treatment or Prevention of Diabetes
Benzodiazepine Cgrp Receptor Antagonists
Benzodiazepine Cgrp Receptor Antagonists
N-Alkyl Phenylcarboxamide Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Hexahydrodiazepinones as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Macrocyclic Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Ophthalmic Compositions for Treating Ocular Hypertension
Fused Phenylalanine Derivatives as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Benzylether and Benzylamino Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Optimized Expression of Hpv 45 L1 in Yeast
Antiprotozoal Imidazopyridine Compounds
Method of Designing Sirnas for Gene Silencing
Benzylether and Benzylamino Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Optimized Expression of Hpv 58 L1 in Yeast
Cyclic Guanidines, Compositions Containing Such Compounds and Methods of Use
Phenylamide and Pyridylamide Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Novel Crystalline Forms of an Inhibitor of 11-Beta-Hydroxysteroid Dehydrogenase Type 1
Cgrp Receptor Antagonists
Process for Large Scale Production of Plasmid Dna by E.Coli Fermentation
Stereoselective Synthesis of a 4,4-Disubstituted Cyclohexanepropanoic Acid
Vla-4 Antagonists
Modified Oncolytic Viruses
Heteroaryl Piperidine Glycine Transporter Inhibitors
Optimized Expression of Hpv 52 L1 in Yeast
3,4-Di-Substituted Cyclobutene-1,2-Diones as Cxc-Chemokine Receptor Ligands
Novel Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Novel Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Novel Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Novel Pyrazolopyridines as Cyclin Dependent Kinase Inhibitors
Novel Imidazopyridines as Cyclin Dependent Kinase Inhibitors
Imidazopyrazines as Cyclin Dependent Kinase Inhibitors
Process for the Synthesis of Trifluorophenylacetic Acids
Method of Treating Edematous Retinal Disorders
Ophthalmic Compositions for Treating Ocular Hypertension
Nucleoside Derivatives as Inhibitors of Rna-Dependent Rna Viral Polymerase
11-Beta-Hydroxysteroid Dehydrogenase 1 Inhibitors Useful for the Treatment of Diabetes, Obesity and Dyslipidemia
Mammalian Receptor Protein DCRS5;Methods of Treatment
Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Antibodies Specific for Plasmacytoid Dendritic Cells
Novel Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Mammalian Cytokines; Related Reagents
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Uses of Il-23 Agonists and Antagonists; Related Reagents
Biaryl Substituted Triazoles as Sodium Channel Blockers
Mass Spectrometry Data Analysis Techniques
Synthesis of 2-Hydroxy-N,N-Dimethyl-3-[[2-[1(R)-(5-Methyl-2-Furanyl)Propyl]Amino]-3,4-Dioxo-1-Cyclobuten-1-Yl]Amino]Benzamide
2-Alkynyl-And 2-Alkenyl-Pyrazolo-[4,3-E]-1,2,4-Triazolo-[1,5-C]-Pyrimidine Adenosine A2A Receptor Antagonists
Cgrp Receptor Antagonists
Tetrahydropyranyl Cyclopentyl Tetrahydropyridopyridine Modulators of Chemokine Receptor Activity
Phosphoric Acid Salt of a Dipeptidyl Peptidase-Iv Inhibitor
Novel Processes for the Preparation of Peripheral Opioid Antagonist Compounds and Intermediates Thereto
Cyclic Amine Bace-1 Inhibitors Having a Benzamide Substituent
Cyclic Amine Bace-1 Inhibitors Having a Heterocyclic Substituent
Tetrahydropyranyl Cyclopentyl Tetrahydropyridopyridine Modulators of Chemokine Receptor Activity
Pharmaceutical Formulation Comprising Dinucleoside Polyphosphates and Salts Thereof
Process for Preparing Substituted 5-Amino-Pyrazolo-[4,3-E]-1,2,4-Triazolo-[1,5-C]-Pyrimidines
[1,2,4]-Triazole Bicyclic Adenosine A2A Receptor Antagonists
Substituted Triazoles as Sodium Channel Blockers
Methods of preventing and treating gastrointestinal dysfunction
Heterocyclic Aspartyl Protease Inhibitors
Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Use of Agonists and Antagonists of Il-23 in the Treatment of Viral Infection
Pyrazolotriazines as Kinase Inhibitors
Sulfur Compounds as Inhibitors of Hepatitis C Virus NS3 Serine Protease
Novel Compounds as Inhibitors of Hepatitis C Virus NS3 Serine Protease
Pyrazolo-[4,3-E]-1,2,4-Triazolo-[1,5-C]-Pyrimidine Adenosine A2A Receptor Antagonists
Method of Treating Skin Inflammation
Benzoxazinyl-Amidocyclopentyl-Heterocyclic Modulators of Chemokine Receptors
2-Alkynyl-And 2-Alkenyl-Pyrazolo-[4,3-E]-1,2,4-Triazolo-[1,5-C]-Pyrimidine Adenosine A2A Receptor Antagonists
Constrained Himbacine Analogs as Thrombin Receptor Antagonists
Compositions Containing Opioid Antagonists
Pyrazole Derivatives, Compositions Containing Such Compounds and Methods of Use
Heterocyclic Aspartyl Protease Inhibitors
Cgrp Receptor Antagonists
Anti-Hypercholesterolemic Compounds
Cetp Inhibitors
Compounds for the Treatment of Inflammatory Disorders
Substituted Amide Beta Secretase Inhibitors
Potassium Channel Inhibitors
Macrocyclic Beta-Secretase Inhibitors
Stable Pegylated Interferon Formulation
Acylsulfonamide Compounds as Inhibitors of Hepatitis C Virus NS3 Serine Protease
Novel Imidazopyridines as Cyclin Dependent Kinase Inhibitors
Thrombin Receptor Antagonists
Pyrazolopyrimidines as Protein Kinase Inhibitors
Trisubstituted 7-Aminopyrazolopryimidines
N-Heteroaryl Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Trisubstituted and Tetrasubstituted Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
Potassium Salt of an Hiv Integrase Inhibitor
Mammalian Cytokines; Receptors; Related Reagents and Methods
Treatment of Diabetes Using Antibodies to Il-23, Il-23 Receptor and Il-17
Pyrazolo [1,5-a] Pyrimidine Adenosine A2A Receptor Antagonists
Processes of Making and Using Pharmaceutical Formulations of Antineoplastic Agents
Compounds for the Treatment of Inflammatory Disorders
Pyrazolotriazines as Kinase Inhibitors
Kinase Inhibitors
Heteroaryl Substituted Pyrazinyl-Piperazine-Piperidines with CXCR3 Antagonist Activity
Novel Heterocyclic Substituted Pyridine or Phenyl Compounds with CXCR3 Antagonist Activity
Heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity
Pyridyl and Phenyl Substituted Piperazine-Piperidines with CXCR3 Antagonist Activity
Piperazine-Piperidines with CXCR3 Antagonist Activity
Pyrazinyl Substituted Piperazine-Piperidines with CXCR3 Antagonist Activity
Amine-Linked Pyridyl and Phenyl Substituted Piperazine-Piperidines with CXCR3 Antagonist Activity
Treatments for Flaviviridae Virus Infection
Spirocyclic Thrombin Receptor Antagonists
Trisubstituted 4-Aminopyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
N-Heteroaryl Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
N-Heteroaryl Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors
System and Method for Automated Selection of T-Cell Epitopes
Synthesis of 2-Hydroxy-N,N-dimethyl-3-[[2-[[1(R)-(5-methyl-2-furanyl)propyl]amino]-3,4-dixo-1cyclobuten-1yl]amino]benzamide
Heterocycles as Nicotinic Acid Receptor Agonists for the Treatment of Dyslipidemia
Macrocyclic Heterocyclic Aspartyl Protease Inhibitors
Substituted Isoindolines as Aspartyl Protease Inhibitors
Bicyclic Guanidine Derivatives as Asparyl Protease Inhibitors, Compositions, and Uses Thereof
Substituted Spiro Iminopyrimidinones as Aspartyl Protease Inhibitors, Compositions, and Methods of Treatment
Preparation and Use of Compounds as Aspartyl Protease Inhibitors
Aspartyl Protease Inhibitors
ILT3 binding molecules and uses therefor
Tyrosine Kinase Inhibitors
P2Y6 Receptor Agonists for Treating Lung Diseases
Hcv NS3 Protease Inhibitors
Novel Spirochromanone Derivatives
Spiropiperidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Phenylcarboxamide Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Compounds for the Treatment of Inflammatory Disorders
Novel High Affinity Quinoline-Based Kinase Ligands
Engineered Anti-Il-23 Antibodies
2-Heteroaryl-Pyrazolo-[4,3-E]-1,2,4-Triazolo-[1,5-C]-Pyrimidine Adenosine A2A Receptor Antagonists
7-[2-[4-(6-Fluoro-3-Methyl-1,2-Benzisoxazol-5-Yl)-1-Piperazinyl]Ethyl]-2-(1-Propynyl)-7H-Pyrazolo-[4,3-E]-[1,2,4]-Triazolo-[1,5-C]-Pyrimidin-5AMINE
Substituted Pyrazolo[1,5-a]Pyrimidness as Protein Kinase Inhibitors
Substituted Pyrazolo[1,5-a] Pyrimidines as Protein Kinase Inhibitors
Substituted Pyrazolo[1,5-a]Pyrimidines as Protein Kinase Inhibitors
Substituted Pyrazolo[1,5-a]Pyrimidines as Protein Kinase Inhibitors
Methods for Using Human Monoclonal Antibodies to Interleukin-5
Substituted Pyrazolo[1,5-a]Pyrimidines as Protein Kinase Inhibitors
Solid Dispersions of Opioid Antagonists
Substituted Heterocyclic Compounds with CXCR3 Antagonist Activity
Pyrazolotriazines as Kinase Inhibitors
Process for the Preparation of Enantiomerically Enriched Beta Amino Acid Derivatives
2,4,6-Substituted Pyridyl Derivative Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Novel Opioid Antagonists
1,3,5-Substituted Phenyl Derivative Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Cetp Inhibitors
Cyclohexylalanine Derivatives as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Hiv Integrase Inhibitors
Acyl Indoles, Compositions Containing Such Compounds and Methods of Use
Non-Immunostimulatory Antibody and Compositions Containing the Same
Heterocyclic Aspartyl Protease Inhibitors
Antibiotic Compound
1,2,4-Oxadiazole Derivatives as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Systems and Methods for Reconstructing Gene Networks in Segregating Populations
3-Monosubstituted Tropane Derivatives as Nociceptin Receptor Ligands
Nitrogen-Containing Heterocyclic Compounds and Methods of Use Thereof
Spirocyclic Compounds
Compounds for the Treatment of Inflammatory Disorders and Microbial Diseases
Interleukin-10 Antibodies
Human Antibodies Interacting with Hiv GP41
Covalently Stabilized Chimeric Coiled-Coil Hiv GP41 N-Peptides with Improved Antiviral Activity.
C-Purine Nucleoside Analogs as Inhibitors of Rna-Dependent Rna Viral Polymerase
Aminocyclohexanes as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Pyrrolidin-3-Yl Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Histone Deacetylase Inhibitors
Histone Deacetylase Inhibitors
Histone Deacetylase Inhibitors
Substituted Pyrazoles, Compositions Containing Such Compounds and Methods of Use
Method for Making Beta-Secretase Co-Crystals Complexed with a Ligand
Method of Evaluating Inflammatory Skin Disorders Using Il-17 and/or Il-19
Identification and Application of Antibiotic Synergy
Method for Identifying Drug-Sensitizing Antisense Dna Fragments and Use Thereof
Ophthalmic Compositions for Treating Ocular Hypertension
Oxazoloisoquinoline Derivatives as Thrombin Receptor Antagonists
Novel Compounds as Inhibitors of Hepatitis C Virus NS3 Serine Protease
Compounds for the Treatment of Inflammatory Disorders
Compounds for the Treatment of Inflammatory Disorders
Compounds for the Treatment of Inflammatory Disorders
Benzenesulfonyl-Chromane, Thiochromane, Tetrahydronaphthalene and Related Gamma Secretase Inhibitors
Potassium Channel Inhibitors
Sulfonyl Compounds as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Vla-4 Antagonists
Methods and Compositions for Treatment of Hematologic Cancers
Histone Deacetylase Inhibitors
Amorphous Form of a Phosphoric Acid Salt of a Dipeptidyl Peptidase-Iv Inhibitor
Carboxamide Spirolactam Cgrp Receptor Antagonists
Monocyclic Anilide Spirolactam Cgrp Receptor Antagonists
Aminopiperidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Tricyclic Anilide Spirolactam Cgrp Receptor Antagonists
Aryl Spirolactam Cgrp Receptor Antagonists
Tricyclic Anilide Spirohydantion Cgrp Receptor Antagonists
Bicyclic Anilide Spirolactam Cgrp Receptor Antagonists
Formulations of Suberoylanilide Hydroxamic Acid and Methods for Producing Same
Spiropiperidine Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer' S Disease
Cyclopropyl Piperidine Glycine Transporter Inhibitors
Thiazolyl MGLUR5 Antagonists and Methods for Their Use
Cgrp Receptor Antagonists
Cgrp Receptor Antagonists
Cgrp Receptor Antagonists
Cgrp Receptor Antagonists
Aryloxy-Substituted Benzimidazole Derivatives
2-Aminopyridine Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Process for {3-[2(R)-[(1R)-1-[3,5-Bis(Trifluoromethyl) Phenyl]Ethoxy]-3(S)-(4-Fluorophenyl)Morpholin-4-Yl]Methyl]-5-Oxo-4,5-Dihydro-[1,2,4]-Triazol-1-Yl}Phosphonic Acid
Fused Aminopiperidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Macrocyclic Tertiary Amine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Novel Heterocyclic Substituted Pyridine Compounds with CXCR3 Antagonist Activity
P1-(2'-Deoxycytidine 5'-)P4-(Uridine 5'-)Tetraphosphate, Tetra-(Alkali Metal) Salt, for Treating Cystic Fibrosis
Nucleoside Derivatives as Inhibitors of Rna-Dependent Rna Viral Polymerase
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compunds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Heterocyclic Aspartyl Protease Inhibitors
Substituted Pyrazolo[1,5-a]Pyrimidines as Cyclin Dependent Kinase Inhibitors
Indoles Having Anti-Diabetic Activity
Cgrp Receptor Antagonists
Monocyclic and Bicyclic Himbacine Derivatives Useful as Thrombin Receptor Antagonists
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Sulfur Compounds as Inhibitors of Hepatitis C Virus NS3 Serine Protease
Fused Ring Thrombin Receptor Antagonists
Aspartyl Protease Inhibitors
Pharmaceutical Formulations and Compositions of a Selective Antagonist of Either CXCR2 or Both CXCR1 and CXCR2 and Methods of Using the Same for Treating Inflammatory Disorders
Adenosine A2A Receptor Antagonists
Substituted Bicyclic and Tricyclic Thrombin Receptor Antagonists
Substituted Piperidines That Increase P53 Activity and the Uses Thereof
Nitrogen-Containing Heterocyclic Compounds and Methods of Use Thereof
Heterocyclic Substituted Piperazine Compounds with CXCR3 Antagonist Activity
Methods for Quantitating Small Rna Molecules
Process for Preparing Substituted 5-Amino-Pyrazolo-[4,3-E]-1,2,4-Triazolo[1,5-C]Pyrimidines
Substituted Pyrazolo[1,5-a]pyrimidines as Cyclin Dependent kinase Inhibitors
Substituted Pyrazolo[1,5-a]Pyrimidines as Cyclin Dependent Kinase Inhibitors
2,3,4,6-Substituted Pyridyl Derivative Compounds Useful As Beta-Secretase Inhibitors For The Treatment Of Alzheimer's Disease
Macrocyclic Aminopyridyl Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Pharmaceutical Formulation Containing a Release Rate Controlling Composition
Pharmaceutical Composition Containing an Anti-Nucleating Agent
Estrogen Receptor Modulators
Bicyclic Pyrimidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Tertiary Carbinamines Having Substituted Heterocycles Which Are Active as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Aminomethyl Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Cgrp Receptor Antagonists
Purification Process for Plasmid Dna
Substituted Monocyclic Cgrp Receptor Antagonists
Antidiabetic Bicyclic Compounds
Optimized Expression of Hpv 45 L1 in Yeast
Novel Compounds That Are Erk Inhibitors
ILT3 Binding Molecules and Uses Therefor
Method of Treating Dry Eye Disease with Purinergic Receptor Agonists
Tyrosine Kinase Inhibitors
Polymorphic Crystalline Forms of Tiacumicin B
Antibodies to Il-17A
Bicyclic and Tricyclic Derivatives as Thrombin Receptor Antagonists
Optimized Expression of Hpv 31 L1 in Yeast
18-Membered Macrocycles and Analogs Thereof
Fused-Aromatic Compounds Having Anti-Diabetic Activity
Composition for Inhibition of Cathepsin K
Cgrp Receptor Antagonists
Quinazolinone T-Type Calcium Channel Antagonists
Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Process for Resolving Chiral Piperidine Alcohol and Process for Synthesis of Pyrazolo[1,5-a] Pyrimidine Derivatives Using Same
Process and Intermediates for the Synthesis of (3-Alkyl-5-Piperidin-1-Yl-3,3A-Dihydro-Pyrazolo[1,5-a]Pyrimidin-7-Yl)-Amino Derivatives and Intermediates
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Therapeutic Compositions
Intelligent Refrigerator for Storing Pharmaceutical Product Containers
Benzothiophene Hydroxamic Acid Derivatives with Carbamate, Urea, Amide and Sulfonamide Substitutions
Benzothiophene Hydroxamic Acid Derivatives
Benzothiophene Derivatives
Hcv NS3 Protease Inhibitors
Aminocyclohexanes as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
1-Hydroxycycloalkanecarboxamide Derivatives
Cyclohexyl Sulphones for Treatment of Cancer
Quinolone M1 Receptor Positive Allosteric Modulators
Benzocycloheptapyridines as Inhibitors of the Receptor Tyrosine Kinase Met
Inhibitors of Akt Activtiy
4-Fluoro-Piperidine T-Type Calcium Channel Antagonists
Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment
Modified Malonate Derivatives
Process for Synthesizing a Cetp Inhibitor
Interactive Product Selection System
Cytoskeletal Active Rho Kinase Inhibitor Compounds, Composition and Use
Spirochromanone Derivatives as Acetyl Coenzyme a Carboxylase (Acc) Inhibitors
Process for Synthesizing a Substituted Pyrazole
Heterocyclic Benzodiazepine Cgrp Receptor Antagonists
Hcv NS3 Protease Inhibitors
Cyclic Ketal Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Fused Aminopiperidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
P38 Kinase Inhibiting Agents
Radiolabeled Glycine Trasporter Inhibitors
Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators
Estrogen Receptor Modulators
Potassium Channel Inhibitors
Substituted Diazepan Orexin Receptor Antagonists
Inhibitors of Akt Activity
Non-Nucleoside Reverse Transcriptase Inhibitors
Crystalline Forms of Carbapenem Antibiotics and Methods of Preparation
Patent:
40,794 →
Application:
11/999,720 →
Amide Substituted Indazoles as Poly(Adp-Ribose)Polymerase(Parp) Inhibitors
Substituted Spirochromanone Derivatives
Biaryl Substituted Triazoles as Sodium Channel Blockers
Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors
Papillomavirus Vaccine Compositions
Cgrp Receptor Antagonists
Triazole Derivatives Which Are Smo Antagonists
Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Cetp Inhibitors
Histone Deacetylase Inhibitors with Aryl-Pyrazolyl-Motifs
Spirohydantoin Aryl Cgrp Receptor Antagonists
Bicyclic Spirohydantoin Cgrp Receptor Antagonists
Spirohydantoin Tricyclic Cgrp Receptor Antagonists
Spirolactam Tricyclic Cgrp Receptor Antagonists
Spirolactam Aryl Cgrp Receptor Antagonists
Spirolactam Bicyclic Cgrp Receptor Antagonists
Imidazolidinone Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Tricyclic Compounds Useful as Inhibitors of Kinases
Spirocyclic Compounds
Pharmaceutical Compositions of Combinations of Dipeptidyl Peptidase-4 Inhibitors with Metformin
Self-Emulsifying Formulations of Cetp Inhibitors
Fused Aminopiperidines as Dipeptidyl Peptidase-4 Inhibitors for the Treatment or Prevention of Diabetes
Morpholine Carboxamide Prokineticin Receptor Antagonists
Aminocyclohexanes as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Triazole Derivatives as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Cetp Inhibitors
Cetp Inhibitors
Cholesteryl Ester Transfer Protein Inhibitors
1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors
Macrolide Polymorphs, Compositions Comprising Such Polymorphs, and Methods of Use and Manufacture Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Substituted Azetidinone Compounds, Processes for Preparing the Same, Formulations and Uses Thereof
Novel Heterocyclic Substituted Pyridine or Phenyl Compounds with CXCR3 Antagonist Activity
Crystalline Polymorphs of a Cxc-Chemokine Receptor Ligand
Antibodies to IL-B50
Method of Treating Skin Inflammation
Method of Treatment of Skin Inflammation
Process for Preparing Substituted 5-Amino-Pyrazolo-[4,3-E]-1,2,4-Triazolo[1,5-C]Pyrimidines
Substituted Monocyclic Cgrp Receptor Antagonists
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Polymer Formulations of Cetp Inhibitors
Pyridine derivative potassium channel inhibitors
A Pharmaceutical Composition Comprising Oxyntomodulin Derivatives and a Method for Reducing Body Weight Using the Composition
Inhibitors of Histone Deacetylase
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Diazepan Orexin Receptor Antagonists
Substituted Imidazole 4-Carboxamides as Cholecystokinin-1 Receptor Modulators
Pyridyl Amide T-Type Calcium Channel Antagonists
Substitued [1,2,4]Triazolo[1,5-a]Pyrazines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Disubstituted Aniline Compounds
Dihydropyrazolopyrimidinone Derivatives
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Aryl-Fused Spirocyclic Compounds
Inhibitors of Janus Kinases
Synthesis of 2-Hydroxy-N,N-Dimethyl-3-[[2-[[1(R)-(5-Methyl-2-Furanyl)Propyl]Amino]-3,4-Dioxo-1-Cyclobuten-1-Yl]Amino]Benzamide
Compounds and Methods for Leukotriene Biosynthesis Inhibition
Eukaryotic Cell Display Systems
Piperidines and Related Compounds for the Treatment of Alzheimer's Disease
Methods and Compositions for Regulating Cell Cycle Progression
Benzyl-Substituted Quinolone M1 Receptor Positive Allosteric Modulators
Tyrosine Kinase Inhibitors
Bridged diazepan orexin receptor antagonists
Method of Treatment Using Fatty Acid Synthesis Inhibitors
Piperidine and Pyrrolidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Substituted Imidazole as Bombesin Receptor Subtype-3 Modulators
Tyrosine Kinase Inhibitors
Process for Preparing Chiral Dipeptidyl Peptidase -Iv Inhibitor Intermediates
Optimized Expression of Hpv 58 L1 in Yeast
1B20 PCSK9 Antagonists
1D05 PCSK9 Antagonists
Antibiotic Macrocycle Compounds and Methods of Mnaufacture and Use Thereof
Hcv NS3 Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
Compounds for the Treatment of Inflammatory Disorders
3-Monosubstituted Tropane Derivatives as Nociceptin Receptor Ligands
Compounds for the Treatment of Inflammatory Disorders
Compounds for the Treatment of Inflammatory Disorders
Compounds for the Treatment of Inflammatory Disorders
Engineered Anti-Il-23 Antibodies
Estrogen Receptor Modulators
Substituted 4-Hydroxypyrimidine-5-Carboxamides
Hepatitis C Virus Vaccine
Macrolide Polymorphs, Compositions Comprising Such Polymorphs, and Methods of Use and Manufacture Thereof
Pharmaceutical Formulations of Antineoplastic Agents
Pyrazole Derivatives, Compositions Containing Such Compounds and Methods of Use
Substituted Pyrazoles, Compositions Containing Such Compounds and Methods of Use
Treatments for Flaviviridae Virus Infection
Cgrp Receptor Antagonists
Refolded Recombinant Beta-Secretase Crystals and Methods for Preparing and Using the Same
Antidiabetic Bicyclic Compounds
Macrocyclic Spiropiperidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Hcv NS3 Protease Inhibitors
Hcv NS3 Protease Inhibitors
Hcv NS3 Protease Inhibitors
Hcv NS3 Protease Inhibitors
2-Aminothiazole-4-Carboxylic Amides as Protein Kinase Inhibitors
2-Aminothiazole-4-Carboxylic Amides as Protein Kinase Inhibitors
Anilinopiperazine Derivatives and Methods of Use Thereof
Spiropiperidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Synthetic Expression Vectors for Insect Cells
Novel Opioid Antagonists
Methods for Delivering a Drug to a Hospital Patient for Short-Term Use While Minimizing Long-Term Use of the Drug
Heterocyclic Aspartyl Protease Inhibitors
P38 Kinase Inhibiting Agents
Surface Display of Whole Antibodies in Eukaryotes
Cyclic Amine Bace-1 Inhibitors Having a Heterocyclic Substituent
7-[2-[4-(6-Fluoro-3-Methyl-1,2-Benzisoxazol-5-Yl)-1-Piperazinyl]Ethyl]-2-(1-Propynyl)-7H-Pyrazolo-[4,3-E]-[1,2,4]-Triazolo-[1,5-C]-Pyrimidin-5-Amine
Macrocyclic Quinoxaline Compounds as Hcv NS3 Protease Inhibitors
Tricyclic Heteroaromatic Compounds as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Engineered Anti-Tslp Antibody
Constrained Spirocyclic Compounds as Cgrp Receptor Antagonists
Aspartyl Protease Inhibitors
Substituted Diazepine Sulfonamides as Bombesin Receptor Subtype-3 Modulators
Spirochromanon Derivatives
Nucleoside Cyclic Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection
4,5-Ring Annulated Indole Derivatives for Treating or Preventing of Hcv and Related Viral Infections
Novel Substituted Pyridines That Are Jnk Inhibitors
5, 6-Ring Annulated Indole Derivatives and Use Thereof
Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection
Bicyclic Spiropiperidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Macrocyclic Polymorphs, Compositions Comprising Such Polymorphs, and Methods of Use and Manufacture Thereof
Inhibitors of Janus Kinases and/or 3-Phosphoinositide-Dependent Protein Kinase-1
Monocyclic Anilide Spirolactam Cgrp Receptor Antagonists
Tripyridyl Carboxamide Orexin Receptor Antagonists
Aminoalkylphenols, Methods of Using and Making the Same
Methods of Inhibiting Tumor Growth Using Blocking Antibodies to Il-23R
18-Membered Macrocycles and Analogs Thereof
Macrocyclic Polymorphs, Compositions Comprising Such Polymorphs and Methods of Use and Manufacture Thereof
Novel Cyclic Benzimidazole Derivatives Useful as Anti-Diabetic Agents
Macrocyclic Beta-Secretase Inhibitors
Hiv Integrase Inhibitors
Methods for Preparing Oxazolidinones and Compositions Containing Them
Optimized Expression of Hpv 52 L1 in Yeast
Cgrp Receptor Antagonists with Tertiary Amide, Sulfanamide, Carbamate and Urea End Groups
Aryl Heterocyclic Cgrp Receptor Antagonists
Bicyclic Anilide Heterocyclic Cgrp Receptor Antagonists
Anti-Mdl-1 Antibodies
Crystalline Forms of Dihydropyrazolopyrimidinone
Methods of Using MIR34 as a Biomarker for TP53 Functional Status
Compositions Comprising MIR34 Therapeutic Agents for Treating Cancer
Spiroindalones
Gamma Secretase Modulators
Oxo Bridged Diazepan Orexin Receptor Antagonists
Pyridyl Piperidine Orexin Receptor Antagonists
Gamma Secretase Modulators
Carboxamide Heterocyclic Cgrp Receptor Antagonists
Tricyclic Anilide Heterocyclic Cgrp Receptor Antagonists
Method for Treating Cystic Fibrosis
Substituted Monocyclic Cgrp Receptor Antagonists
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Mammalian Expression Vector Puhab
Macrocyclic Heterocyclic Aspartyl Protease Inhibitors
Cetp Inhibitors
Hepatitis C Virus Vaccine
Novel Antibacterial Agents for the Treatment of Gram Positive Infections
Cyclic Amine Bace-1 Inhibitors Having a Benzamide Substituent
Novel Heterocyclic Substituted Pyridine Compounds with CXCR3 Antagonist Activity
Cetp Inhibitors Derived from Benzoxazole Arylamides
Cetp Inhibitors Derived from Benzoxazole Arylamides
Cetp Inhibitors Derived from Benzoxazole Arylamides
Inhibitors of Janus Kinases
Tetrahydropyranochromene Gamma Secretase Inhibitors
Process and Intermediates for the Synthesis of 1,2-Substituted 3,4-Dioxo-1-Cyclobutene Compounds
4-Carboxybenzylamino Derivatives as Histone Deacetylase Inhibitors
Pyridyl Derivatives as Histone Deacetylase Inhibitors
Soluble Epoxide Hydrolase Inhibitors, Compositions Containing Such Compounds and Methods of Treatment
Benzenesulfonyl-Chromane, Thiochromane, Tetrahydronaphthalene and Related Gamma Secretase Inhibitors
Macrocyclic Compounds As Antiviral Agents
Heterocyclic Amide Compounds as Protein Kinase Inhibitors
Pyrazolo[1,5-A]Pyrimidine Derivatives
Heterocyclic Compounds as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
6-SUBSTITUTED SULFONYL AZABICYCLO[3.2.1]OCTANES USEFUL TO INHIBIT 11Beta-HYDROXYSTEROID DEHYDROGENASE TYPE-1
SUBSTITUTED BICYCLIC PIPERIDINYL-AND PIPERAZINYL- SULFONAMIDES USEFUL TO INHIBIT 11beta-HYDROXYSTEROID DEHYDROGENASE TYPE-1
Method of Treating Inherited Severe Neutropenia
Soluble Guanylate Cyclase Activators
2,3-Substituted Azaindole Derivatives for Treating Viral Infections
Substituted Indole Derivatives and Methods of Use Thereof
Process for the Production of a Crystalline Glucagon Receptor Antagonist Compound
Inhibitors of Janus Kinases
Formulations of Suberoylanilide Hydroxamic Acid and Methods for Producing Same
Formulations of Suberoylanilide Hydroxamic Acid and Methods for Producing Same
Methods for Inhibiting Protein Kinases
Compounds for the Treatment of Inflammatory Disorders
Heterocyclic Aspartyl Protease Inhibitors
Beta-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors for the Treatment of Diabetes
Crystalline Form of R)-3-(4-(2-(2-Methyltetrazol-5-Yl)Pyridin- 5-Yl)-3-Fluorophenyl)-5-Hydroxymethyl Oxazolidin-2-One Dihydrogen Phosphate
Interleukin-10 Antibodies
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Indole Derivatives as CRTH2 Receptor Antagonists
Soluble Guanylate Cyclase Activators
Tricyclic Anilide Spirolactam Cgrp Receptor Antagonists
Quinolizidinone M1 Receptor Positive Allosteric Modulators
Thiazole Derivatives as Protein Kinase Inhibitors
Thiazole Carboxamide Derivatives and Their Use to Treat Cancer
Compounds for Inhibiting Ksp Kinesin Activity
Antidiabetic Tricyclic Compounds
Heterocycle Phenyl Amide T-Type Calcium Channel Antagonists
Substituted Diazepan Orexin Receptor Antagonists
Bicyclic Heterocycle Derivatives and Their Use as Modulators of the Activity of GPR119
Anti-PCSK9 and Methods for Treating Lipid and Cholesterol Disorders
Tryptamine Sulfonamides as 5-HT6 Antagonists
P2X3 Receptor Antagonists for Treatment of Pain
P2X3 Receptor Antagonists for Treatment of Pain
Non-Nucleoside Reverse Transcriptase Inhibitors
3-Heterocyclic Substituted Indole Derivatives and Methods of Use Thereof
3-Aminosulfonyl Substituted Indole Derivatives and Methods of Use Thereof
Novel Modulators of Cell Cycle Checkpoints and Their Use in Combination with Checkpoint Kinase Inhibitors
Morpholinone Compounds as Factor Ixa Inhibitors
Gamma Secretase Modulators
Inhibitors of Janus Kinases
3,4-Substituted Pyrrolidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Alternative Forms of the Phosphodiesterase-4 Inhibitor N-Cyclopropyl-1-{3-[(1-Oxidopryidin-3-Yl)Ethynyl] Phenyl}-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxyamide
Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1
Inhibitors of the Renal Outer Medullary Potassium Channel
Benzylether and Benzylamino Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Genetic Markers Associated with Interferon-Alpha Response
Morpholinone Compounds as Factor Ixa Inhibitors
Process for Preparing N-Alkylated Hydroxypyrimidinone Compounds
Heterocyclic Aspartyl Protease Inhibitors
3-Substituted-4-Oxo-3,4-Dihydro-Imidazo[5,1-D]-1,2,3,5-Tetrazine-8-Carboxylic Acid Amides and Their Use
Methods for Inhibiting Tumor Growth or Reducing Metastatic Burden in a Subject by Administering FDF03 Antibodies
Process for Preparing N-Substituted Hydroxypyrimidinone Carboxamides
Pharmaceutically Acceptable Salts of 2-{4-[(3S)-Piperidin-3-Yl]Phenyl}-2H-Indazole-7-Carboxamide
Beta-Lactamase Inhibitors
Quinolizidinone M1 Receptor Positive Allosteric Modulators
Cetp Inhibitors
Method of Treating Skin Inflammation
Cgrp Receptor Antagonists
Intelligent Refrigerator for Storing Pharmaceutical Product Containers
SYN3 Compositions and Methods
Processes of Making Pharmaceutical Formulations of Antineoplastic Agents
System and Method for Segmenting M-Mode Ultrasound Images Showing Blood Vessel Wall Motion Over Time
Substituted Amide Beta Secretase Inhibitors
Process for {3-[2(R)-[(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy]-3(S)-(4-Fluorophenyl)Morpholin-4-Yl]Methyl]-5-Oxo-4,5-Dihydro-[1,2,4]-Triazol-1-Yl}Phosphonic Acid
Engineered Anti-Tslpr Antibodies
Prodrugs of Cgrp Receptor Antagonists
Quinolizidinone M1 Receptor Positive Allosteric Modulators
Fused Pyridone M1 Receptor Positive Allosteric Modulators
Imidazobenzazepine Cgrp Receptor Antagonists
Substituted 5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Spirocyclic Compounds
Antibodies to Il-17A
Antibodies to Il-17A
Novel Compounds That Are Erk Inhibitors
Therapeutic Compounds
Tetrahydrofuropyridones
Tetrahydrothieno Pyridines
Tetrahydro-1H-Pyrrolo Fused Pyridones
2-Aminoimidazole Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
1,2,4-Triazolo[4,3-C]Pyrimidin-3-One and Pyrazolo[4,3-E]-1,2,4-Triazolo[4,3-C]Pyrimidin-3-One Compounds for Use as Adenosine A2A Receptor Antagonists
AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
Pd-1 Binding Proteins
Quinolizidinone M1 Receptor Positive Allosteric Modulators
Monocyclic Cgrp Receptor Antagonists
Hydroxymethyl Pyrrolidines as Beta 3 Adrenergic Receptor Agonists
Substituted Cyclopropyl Compounds, Compositions Containing Such Compounds and Methods of Treatment
P2Y6 Receptor Agonists for Treating Lung Diseases
Heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity
Bridged Bicyclic Rho Kinase Inhibitor Compounds, Composition and Use
Aminopyrimidines as Syk Inhibitors
Phenyl-Substituted 2-Imino-3-Methyl Pyrrolo Pyrimidinone Compounds as Bace-1 Inhibitors, Compositions, and Their Use
Thiophenyl-Substituted 2-Imino-3-Methyl Pyrrolo Pyrimidinone Compounds as Bace-1 Inhibitors, Compositions, and Their Use
Inhibitors of Janus Kinases
Cyclobutyl Sulfones as Notch Sparing Gamma Secretase Inhibitors
Hcv NS3 Protease Inhibitors
Spiroazaindoles
Glucagon Receptor Antagonists, Compositions, and Methods for Their Use
Process for the Preparation of an Orexin Receptor Antagonist
Heterocyclic Compounds as Factor Ixa Inhibitors
Efficient Production of Heterologous Proteins Using Mannosyl Transferase Inhibitors
Novel Substituted Azabenzoxazoles
SUBSTITUTED [1,2,4]TRIAZOLO[4',3':1,6]PYRIDO[2,3-b]-PYRAZINES OF THE FORMULA D
Inhibitors of Akt Activity
Process for Producing Bicycloaniline Derivatives
Branched 3- and 6-Substituted Quinolines as Cgrp Receptors Antagonists
Tricyclic Indole Derivatives and Methods of Use Thereof
Inhibitors of Janus Kinases
Inhibitors of Janus Kinases
Bicyclic Heterocycle Derivatives and Use Thereof as GPR119 Modulators
Bicyclic Heterocycle Derivatives and Methods of Use Thereof
Pyridyl Amide T-Type Calcium Channel Antagonists
Thiazolyl MGLUR5 Antagonists and Methods for Their Use
15-Valent Pneumococcal Polysaccharide-Protein Conjugate Vaccine Composition
Fused Tricyclic Silyl Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Substituted Naphthyridine Compounds as Inhibitors of Akt Activity
Pharmaceutical Composition Comprising Oxyntomodulin Derivatives and a Method for Reducing Body Weight Using the Composition
Inhibitors of Janus Kinases
N-Heterocyclic M1 Receptor Positive Allosteric Modulators
Oxazole Derivatives Useful as Inhibitors of Faah
Pyrazolo[1,5-A]Pyridines as Mark Inhibitors
3- and 6-Quinolines with N-Attached Heterocyclic Cgrp Receptor Antagonists
Substituted Pyridine and Pyrimidine Derivatives and Their Use in Treating Viral Infections
Ethynyl-Substituted Pyridine and Pyrimidine Derivatives and Their Use in Treating Viral Infections
Azo-Substituted Pyridine and Pyrimidine Derivatives and Their Use in Treating Viral Infections
Ethenyl-Substituted Pyridine and Pyrimidine Derivatives and Their Use in Treating Viral Infections
Non-Amidic Linkers with Branched Termini as Cgrp Receptor Antagonists
Il-8 Biomarker for Monitoring Cancer Treatment with Certain Erk Inhibitors
Monocyclic Amide Cgrp Receptor Antagonists
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Peptides as NS3-Serine Protease Inhibitors of Hepatitis C Virus
Patent:
43,298 →
Application:
13/068,159 →
1,3-Oxazolidin -2-One Derivatives Useful as Cetp Inhibitors
Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment of type 2 diabetes
Method for Selecting Sirnas from a Plurality of Sirnas for Gene Silencing
Identification and Application of Antibiotic Synergy
Heterocyclic Aspartyl Protease Inhibitors
Bicyclic Dihydroimidazolone Cgrp Receptor Antagonists
Compounds for the Treatment of Inflammatory Disorders
Compounds for the Treatment of Inflammatory Diseases
Quinolizidinone M1 Receptor Positive Allosteric Modulators
Spiro-Imidazolone Derivatives as Glucagon Receptor Antagonists
Cgrp Receptor Antagonists
Prodrugs of Oxazolidinone Cetp Inhibitors
Isonicotinamide Orexin Receptor Antagonists
2,4-Disubstituted Pyrrolidine Orexin Receptor Antagonists
2,5-Disubstituted Morpholine Orexin REceptor Antagonists
2,5-Disubstituted Piperidine Orexin Receptor Antagonists
Novel Cyclic Benzimidazole Derivatives Useful as Anti-Diabetic Agents
2,5-Disubstituted Piperidine Orexin Receptor Antagonists
Disubstituted Azepan Orexin Receptor Antagonists
2,3-Disubstituted Piperidine Orexin Receptor Antagonists
Novel Cyclic Benzimidazole Derivatives Useful as Anti-Diabetic Agents
Novel Cyclic Benzimidazole Derivatives Useful as Anti-Diabetic Agents
P2X3, Receptor Antagonists for Treatment of Pain
Benzimidazole and Aza-Benzimidazole Carboxamides
Soluble Guanylate Cyclase Activators
Live, Attenuated Respiratory Syncytial Virus
Quinolone Neuropeptide S Receptor Antagonists
Imidazoisoindole Neuropeptide S Receptor Antagonists
Inhibitors of Fatty Acid Binding Protein (Fabp)
Gamma Secretase Modulators
Gamma Secretase Modulators
Beta G1-Igg Intron for Enhanced Anti-IGF1R Expression
Aryl Methyl Benzoquinazolinine M1 Receptor Positive Allosteric Modulators
Nitrooxy Cycloalkane Derivatives
Biaryl Carboxamides
Novel Crystalline Forms of an Inhibitor of 11-Beta-Hydroxysteroid Dehydrogenase Type 1
Triazole Derivatives for Treatment of Alzheimer's Disease
Glucagon Receptor Antagonist Compounds
Gamma Secretase Modulators
Pyrimidine Derivatives as Gpcr Modulators for Use in the Treatment of Obesity and Diabetes
Bicyclic Heterocycle Derivatives and Methods of Use Thereof
Imidazo[1,2-A]Pyridines and Imidazo[1,2-B]Pyridazines as Mark Inhibitors
Trifluoromethylsulfonamide Gamma Secretase Inhibitor
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Dihydrofolate Reductase Inhibitors
Antibiotic Compositions for the Treatment of Gram Negative Infections
Patent:
8,415,307 →
Application:
13/167,495 →
Fused Ring Thrombin Receptor Antagonists
Process for Large Scale Production of Plasmid Dna by E. Coli Fermentation
Heterocyclic Aspartyl Protease Inhibitors
Spiropyrrolidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Pyrazolo [4,3-C] Cinnolin-3-One M1 Receptor Positive Allosteric Modulators
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Bicyclic Compounds as Inhibitors of Diacylglycerol Acyltransferase
Substituted Quinoxalines as Inhibitors of Fatty Acid Binding Protein
Antagonists of PCSK9
Ether Benzotriazole Derivatives
Surface Display of Whole Antibodies in Eukaryotes
Combination Cancer Therapy with an Akt Inhibitor and Other Anticancer Agents
Imidazole Derivatives Useful as Modulators of Faah and as Faah Imaging Agents
Inhibitors of Akt Activity
Cgrp Receptor Antagonists
P2X3 Receptor Antagonists for Treatment of Pain
P2X3 Receptor Antagonists for Treatment of Pain
P2X3, Receptor Antagonists for Treatment of Pain
Bicyclic Piperidine and Piperazine Derivatives as Gpcr Modulators for the Treatment of Obesity, Diabetes and Other Metabolic Disorders
Inhibitors of Hepatitis C Virus Replication
Inhibitors of Akt Activity
Pyrazolo[1,5-A]Pyrimidine Derivatives as Mtor Inhibitors
Heterocyclic Fused Cinnoline M1 Receptor Positive Allosteric Modulators
P38 Kinase Inhibiting Agents
Benzenesulfonyl-Chromane, Thiochromane, Tetrahydronaphthalene and Related Gamma Secretase Inhibitors
Cytoskeletal Active Rho Kinase Inhibitor Compounds, Composition and Use
Antibiotic Macrocycle Compounds and Methods of Manufacture and Use Thereof
Chromatography Media
Patent:
9,156,879 →
Application:
13/285,433 →
Processes of Making and Using Pharmaceutical Formulations of Antineoplastic Agents
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Pyrrolidine-Derived Beta 3 Adrenergic Receptor Agonists
Fused Tricyclic Aryl Compounds Useful for the Treatment of Viral Diseases
Radiolabeled PDE10 Inhibitors
Hiv Protease Inhibitors
Process for the Synthesis of Azetidinones
MAMMALIAN EXPRESSION VECTOR pUHAB
Antiviral Compounds Composed of Three Aligned Aryl Moieties to Treat Diseases such as Hepatitis C
Antiviral Compounds of Three Linked Aryl Moieties to Treat Diseases Such as Hepatitis C
3-Substituted-8-Substituted-3H-Imidazo[5,1-d][1,2,3,5]tetrazin-4-one Compounds and Their Use
Thiophenes as Glucagon Receptor Antagonists, Compositions, and Methods for Their Use
Substituted-1,3,8-Triazaspiro[4.5]Decane-2,4-Diones
Substituted 4-Hydroxypyrimidine-5-Carboxamides
FUSED TRICYCLIC COMPOUNDS AS NOVEL mTOR INHIBITORS
Substituted 4-Hydroxypyrimidine-5-Carboxamides
Platelet-Activating Factor Receptor Antagonists
Quinolinone PDE2 Inhibitors
Hepatitis C Virus NS3 Protease Inhibitors
Enantio- and Stereo-Specific Syntheses of Beta-Amino-Alpha- Hydroxy Amides
Anti-Gitr Antibodies
4, 5, 6-Trisubstituted Pyrimidine Derivatives as Factor Ixa Inhibitors
Process for Preparing a 2-Alkynyl Substituted 5-Amino-Pyrazolo-[4,3-E]-1,2,4-Triazolo[1,5-C]Pyrimidine
Substituted Cyclopropyl Compounds, Compositions Containing Such Compounds and Methods of Treatment
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Substituted Aminopiperidines as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
Pentafluorosulfur Imino Heterocyclic Compounds as Bace-1 Inhibitors, Compositions, and Their Use
Ether Benzotriazole Derivatives
Heterocyclic Amide Compounds as Protein Kinase Inhibitors
Pentafluorosulfur Imino Heterocyclic Compounds as Bace-1 Inhibitors, Compositions and Their Use
Novel Pyrrolidine Derived Beta 3 Adrenergic Receptor Agonists
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions and Their Use
Pyranyl Aryl Methyl Benzoquinazolinone M1 Receptor Positive Allosteric Modulators
Novel Pyrrolidine Derived Beta 3 Adrenergic Receptor Agonists
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Modulators of Cell Cycle Checkpoints and Their Use in Combination with Checkpoint Kinase Inhibitors
Gyrase Inhibitors
Heterocyclic-Fused Pyrazolo[4,3-C] Pyridin-3-One M1 Receptor Positive Allosteric Modulators
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Heterocyclic Aspartyl Protease Inhibitors
Primary Amine Diazeniumdiolate Heterocyclic Derivatives
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
Heterocyclic Aspartyl Protease Inhibitors
Aspartyl Protease Inhibitors
Method of Treatment Using Fatty Acid Synthesis Inhibitors
Compositions Containing Opioid Antagonists
Novel Opioid Antagonists
Tiacumicin Production
Preparation of Crystalline Forms of Dihydropyrazolopyrimidinone
Tricyclic Gyrase Inhibitors
Novel Pyrrolidines as Glucagon Receptor Antagonists, Compositions, and Methods for Their Use
Novel Compounds That Are Erk Inhibitors
Crystalline Hydrochloride Salts of C-Met Kinase Inhibitors
Inhibitors of Fatty Acid Binding Protein (Fabp)
Quinolinone-Pyrazolone M1 Receptor Positive Allosteric Modulators
Heterocycle Amide T-Type Calcium Channel Antagonists
Diuretics
Method for Producing Proteins in Pichia Pastoris That Lack Detectable Cross Binding Activity to Antibodies Against Host Cell Antigens
Diaryl Ether Derivatives as Notch Sparing Gamma Secretase Inhibitors
Substituted Piperidines That Increase P53 Activity and the Uses Thereof
AX1 PCSK9 Antagonists
AX132 PCSK9 Antagonists
Solid Pharmaceutical Compositions Containing an Integrase Inhibitor
Bridged Bicyclic Piperidine Derivatives and Methods of Use Thereof
Diuretics
Engineered Anti-Tslp Antibody
Substituted Biaryl Derivatives and Methods of Use Thereof
Drug Products, Dry Powder Inhalers and Polyflux Collider Arrangements
Quinolizidinone Carboxamide M1 Receptor Positive Allosteric Modulators
SUBSTITUTED [1,2,4]TRIAZOLO[4,3-alpha]QUINOXALINES AS ADENOSINE A2a RECEPTOR ANTAGONISTS
Pyrimidine Ether Derivatives and Methods of Use Thereof
Pyridoquinazolinone M1 Receptor Positive Allosteric Modulators
Quinoline Amide M1 Receptor Positive Allosteric Modulators
Aminopyrimidines as Syk Inhibitors
Aminopyrimidines as Syk Inhibitors
Methods of Treating Multiple Sclerosis, Rheumatoid Arthritis and Inflammatory Bowel Disease Using Agonists Antibodies to Pilr-Alpha
Aminobenzoquinazolinone M1 Receptor Positive Allosteric Modulators
Cell Line 3M
Oxadiazole Beta Carboline Derivatives as Antidiabetic Compounds
PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
Substituted Aminotetrahydrothiopyrans and Derivatives Thereof as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
Pyrazolo[1,5-A]Pyrimidines as Mark Inhibitors
Cycloalkyl-Fused Tetrahydroquinolines as CRTH2 Receptor Modulators
Production of Glycoproteins with Reduced O-Glycosylation
Engineered Anti-Il-23P19 Antibodies
Engineered Anti-Tslp Antibody
Engineered Anti-Tslp Antibody
Methods for Delivering a Drug to a Hospital Patient for Short-Term Use While Minimizing Long-Term Use of the Drug
Heterocyclic Aspartyl Protease Inhibitors
Interleukin-10 Antibodies
Thiazolyl MGLUR5 Antagonists and Methods for Their Use
Pyridyl Piperidine Orexin Receptor Antagonists
Anti-ILT5 Antibodies and ILT5-Binding Antibody Fragments
Immunoregulation by Anti-ILT5 Antibodies and ILT5-Binding Antibody Fragments
8-METHYL-1-PHENYL-IMIDAZOL[1,5-a]PYRAZINE COMPOUNDS AS Lck INHIBITORS AND USES THEREOF
Preparation of Lamivudine Form I
Diazeniumdiolate Cyclopentyl Derivatives
Novel Cyclic Benzimidazole Derivatives Useful as Anti-Diabetic Agents
Substituted Pyridine and Pyrimidine Derivatives and Their Use in Treating Viral Infections
Method for Increasing N-Glycosylation Site Occupancy on Therapeutic Glycoproteins Produced in Pichia Pastoris
Positive Allosteric Modulators of MGLUR2
Inhibitors of Catechol O-Methyl Transferase and Their Use in the Treatment of Psychotic Disorders
Efficient Production of Heterologous Proteins Using Mannosyl Transferase Inhibitors
Cyclic Amine Bace-1 Inhibitors Having a Benzamide Substituent
Cytoskeletal Active Rho Kinase Inhibitor Compounds, Composition and Use
Tazobactam Arginine Compositions
Patent:
8,476,425 →
Application:
13/628,742 →
Substituted Pyrimidines
Oxazole Derivatives Useful as Modulators of Faah
Oxazole Derivatives Useful as Modulators of Faah
Soluble Guanylate Cyclase Activators
Process for Synthesizing 6-Bromo-3-1-(1-Methyl-1H-Pyrazol-4-Yl)-5-(3(R)-Piperidinyl)Pyrazolo[1,5-A]Pyrimidin-7-Amine
Novel Spiropiperidine Prolylcarboxypeptidase Inhibitors
Prolylcarboxypeptidase Inhibitors
Heterocyclic Quinolizine Derived M1 Receptor Positive Allosteric Modulators
Novel Prolylcarboxypeptidase Inhibitors
Novel Prolylcarboxypeptidase Inhibitors
Substituted Seven-Membered Heterocyclic Compounds as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
Novel Beta 3 Adrenergic Receptor Agonists
2-Pyridyloxy-4-Nitrile Orexin Receptor Antagonists
Therapeutic Combination of Daptomycin and Protein Synthesis Inhibitor Antibiotic, and Methods of Use
Fused Bicyclic Oxazolidinone Cetp Inhibitor
Naphthalene Carboxamide M1 Receptor Positive Allosteric Modulators
Diazeniumdiolate Cyclohexyl Derivatives
Soluble Guanylate Cyclase Activators
Method for Preparing Antibodies Having Improved Properties
Positive Allosteric Modulators of MGLUR2
Novel Prolylcarboxypeptidase Inhibitors
Novel Prolylcarboxypeptidase Inhibitors
Novel Heterocyclic Compounds as Erk Inhbitors
Heterocyclic Fused Phenanthrolinone M1 Receptor Positive Allosteric Modulators
Posaconazole Intravenous Solution Formulations Stabilized by Substituted Beta-Cyclodextrin
Tetrahydroquinoline Amide M1 Receptor Positive Allosteric Modulators
Amino-Pyridine-Containing Spleen Tyrosine Kinase (Syk) Inhibitors
Pyrazolo [4,3-C] Cinnolin-3-One M1 Receptor Positive Allosteric Modulators
Spirocyclic Compounds
4-Carboxybenzylamino Derivatives as Histone Deacetylase Inhibitors
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Indole Derivatives as CRTH2 Receptor Antagonists
Isoindolone M1 Receptor Positive Allosteric Modulators
Substituted Imidazolones, Compositions Containing Such Compounds and Methods of Use
Spiroxazolidinone Compounds
Aldosterone Synthase Inhibitors
Novel Pyrrolidine Derived Beta 3 Adrenergic Receptor Agonists
Novel Cyclic Azabenzimidazole Derivatives Useful as Anti-Diabetic Agents
Fused-Imidazoyl Compounds Useful as Antimicrobial Agents
Positive Allosteric Modulators of MGLUR2
Pyrazolopyrimidine Pde 10 Inhibitors
Substituted Pyrazolo[1,5-a]pyrido[3.2-e]pyrimidin-6-one Inhibitors of Mammalian Target of Rapamycin
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS mTOR INHIBITORS
Indazole Derivatives Useful as Erk Inhibitors
Alkoxy Pyrimidine PDE10 Inhibitors
Fused Pyrazole Derivatives as Novel Erk Inhibitors
Dihydrobenzoquinazolinone M1 Receptor Positive Allosteric Modulators
Tazobactam Arginine Compositions
Inhibiting Transient Receptor Potential Ion Channel TRPA1
Antibiotic Macrocycle Compounds and Methods of Manufacture and Use Thereof
Antibiotic Compositions for the Treatment of Gram Negative Infections
Formulations for Cathepsin K Inhibitors
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
1,3,4-Oxadiazole and 1,3,4-Thiadiazole Beta-Lactamase Inhibitors
Isoxazole Beta-Lactamase Inhibitors
1,2,4-Oxadiazole and 1,2,4-Thiadiazole Beta-Lactamase Inhibitors
Beta-Lactamase Inhibitors
Fused Tricyclic Inhibitors of Mammalian Target of Rapamycin
Fused Tetracycle Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Quinazolinone-Type Compounds as CRTH2 Antagonists
Process for the Preparation of an Orexin Receptor Antagonist
Bicyclic Diamines as Janus Kinase Inhibitors
Leucine-Rich Repeat Kinase Enzyme Activity
Inhibitors of the Renal Outer Medullary Potassium Channel
Soluble Guanylate Cyclase Activators
Novel Compounds That Are Erk Inhibitors
Recombinant Subunit Dengue Virus Vaccine
Novel Pyrrolidine Derived Beta 3 Adrenergic Receptor Agonists
Inhibitors of the Renal Outer Medullary Potassium Channel
Cyclic Amine Substituted Oxazolidinone CETP Inhibitor
Diazeniumdiolate Heterocyclic Derivatives
N-SULFONYLATED TETRAHYDROQUINOLINES AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Selective Glycosidase Inhibitors and Uses Thereof
Piperidinone Carboxamide Indane Cgrp Receptor Antagonists
Bridged Bicyclic Rho Kinase Inhibitor Compounds, Compositions and Use
Inhibitors of the Renal Outer Medullary Potassium Channel
Hcv NS3 Protease Inhibitors
Yeast Strain for the Production of Proteins with Modified O-Glycosylation
Mineralocorticoid Receptor Antagonists
Positive Allosteric Modulators of the Alpha 7 Nicotinic Acetylcholine Receptor and Uses Thereof
Rorgammat Inhibitors
Surface, Anchored Fc-Bait Antibody Display System
Tricyclic Heterocycles Useful as Dipeptidyl Peptidase-Iv Inhibitors
Indazole Derivatives Useful as Erk Inhibitors
Fused Heterocyclic Indane Carboxamide Cgrp Receptor Antagonists
Fused Heterocyclic Azaindane Carboxamide Cgrp Receptor Antagonists
Quinoxalines and Aza-Quinoxalines as CRTH2 Receptor Modulators
Quinolines and Aza-Quinolines as CRTH2 Receptor Modulators
Fused Bicyclic Heterocycles Useful as Dipeptidyl Peptidase-Iv Inhibitors
Process for the Preparation of an Orexin Receptor Antagonist
Tetracyclic Xanthene Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Piperidinone Carboxamide Spirohydantoin Cgrp Receptor Antagonists
Amidopyrazole Inhibitors of Interleukin Receptor-Associated Kinases
Stable Formulations of Antibodies to Human Programmed Death Receptor Pd-1 and Related Treatments
Gamma Secretase Inhibitors
Pyrrolidine-Fused Thiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
C5-C6 Oxacyclic-Fused Thiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Aryl Methyl Benzoquinazolinone M1 Receptor Positive Allosteric Modulators
Cephalosporin Compound
Patent:
8,809,314 →
Application:
14/020,230 →
Hiv Protease Inhibitors
IL-8 level as a determinant of responsivity of a cancer to treatment
Bridged and Fused Antidiabetic Compounds
Non-Nucleoside Reverse Transcriptase Inhibitors
Substituted 1,3-Benzothiazol-2(3H)-Ones and [1,3]Thiazolo[5,4-B]Pyridin-2(1H)-Ones as Positive Allosteric Modulators of MGLUR2
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Methods for Preparing Oxazolidinones and Compositions Containing Them
Oxazole Derivatives Useful as Inhibitors of Faah
Pavec
Substituted Cycloproply Compounds, Compositions Containing Such Compounds and Methods of Treatment
5-Substituted Iminothiazines and Their Mono- and Dioxides as Bace Inhibitors, Compositions, and Their Use
Mineralocorticoid Receptor Antagonists
2'-Azido Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
2'-Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
2'-Cyano Substituted Nucleoside Derivatives and Methods of Use Thereof Useful for the Treatment of Viral Diseases
Aldosterone Synthase Inhibitors
Alkyne Benzotriazole Derivatives
Cyclohexene Benzotriazole Derivatives
Aminomethyl Biaryl Benzotriazole Derivatives
Diazeniumdiolate Cyclohexyl Derivatives
Bipyridylaminopyridines as Syk Inhibitors
Pyridyl Aminopyridines as Syk Inhibitors
Aminopyrimidines as Syk Inhibitors
N-Methyl Tetrahydroquinoline M1 Receptor Positive Allosteric Modulators
N-Linked Quinolineamide M1 Receptor Positive Allosteric Modulators
Aryloxmethyl Cyclopropane Derivatives as PDE10 Inhibitors
N-Linked Lactam M1 Receptor Positive Allosteric Modulators
Immobilized Transaminases and Process for Making and Using Immobilized Transaminase
Method for Preparing Fc Containing Polypeptides Having Improved Properties
Novel Crystalline Forms of a Dipeptidyl Peptidase-Iv Inhibitor
Process for Preparing Chiral Dipeptidyl Peptidase-Iv Inhibitors
Tricyclic Heterocycles Useful as Dipeptidyl Peptidase-Iv Inhibitors
Imidazopyridin-2-One Derivatives
Substituted Cyclopropyl Compounds, Compositions Containing Such Compounds, and Methods of Treatment
Factor Ixa Inhibitors
Substituted Imidazopyridines as HDM2 Inhibitors
Cyclic Amide Bace-1 Inhibitors Having a Benzamide Substituent
Inhibiting the Transient Receptor Potential A1 Ion Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Methods of Modulating Cytokine Activity; Related Reagents
Preparation of Crystalline Forms of Dihydropyrazolopyrimidinone
Novel Opioid Antagonists
Cephalosporin Compositions and Methods of Manufacture
Ceftolozane-Tazobactam Pharmaceutical Compositions
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Preparation and Use of Compounds as Protease Inhibitors
5'-Substituted Nucleoside Analogs and Methods of Use Thereof for the Treatment of Viral Diseases
5'-Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Fused Tricyclic Compounds as Mtor Inhibitors
Selective Glycosidase Inhibitors and Uses Thereof
Crystal Forms of a Hcv Protease Inhibitor
Methods and Intermediates for Preparing Macrolactams
Process and Intermediates for Preparing Macrolactams
Substituted Benzopiperazines as Cetp Inhibitors
Pyrimidine PDE10 Inhibitors
Inhibitors of the Renal Outer Medullary Potassium Channel
2-Spiro-Substituted Iminothiazines and Their Mono-and Dioxides as Bace Inhibitors, Compositions and Their Use
Cold Storage System for Storing Pharmaceutical Product Containers
Ceftolozane Antibiotic Compositions
Anti-Gitr Antibodies
Ceftolozane-Tazobactam Pharmaceutical Compositions
Solid Forms of Ceftolozane
Patent:
8,906,898 →
Application:
14/289,224 →
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Yeast Strain for the Production of Proteins with Terminal Alpha-1,3-Linked Galactose
Gamma Secretase Inhibitors
Heterocyclic-Substituted Benzofuran Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Tetracyclic Heterocycle Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Substitued Benzofuran Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Conditional Replicating Cytomegalovirus as a Vaccine for Cmv
Compositions and Methods for Treating Cancer
Inhibitors of the Renal Outer Medullary Potassium Channel
Cycloalkylnitrile Pyrazole Carboxamides as Janus Kinase Inhibitors
Acyclic Cyanoethylpyrazoles as Janus Kinase Inhibitors
Cyanomethylpyrazole Carboxamides as Janus Kinase Inhibitors
Triazolopyridyl Compounds as Aldosterone Synthase Inhibitors
Substituted Pyrimidines
Pyrazolopyridyl Compounds as Aldosterone Synthase Inhibitors
Substituted Pyrimidines
Triazolyl PDE10 Inhibitors
1,3 Substituted Azetidine PDE10 Inhibitors
Azaindoles as Janus Kinase Inhibitors
2-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors
Phenyl Carboxamide-Containing Spleen Tyrosine Kinase (Syk) Inhibitors
3-Pyridyl Carboxamide-Containing Spleen Tyrosine Kinase (SYK) Inhibitors
Pharmaceutical Compositions That Inhibit Disproportionation
Mineralocorticoid Receptor Antagonists
Mineralocorticoid Receptor Antagonists
Mineralocorticoid Receptor Antagonists
Substituted Piperidinyl Compounds Useful as GPR119 Agonists
2,5-Disubstituted Thiomorpholine Orexin Receptor Antagonists
Factor Ixa Inhibitors
Novel Compounds That Are Erk Inhibitors
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Benzoxazolinone Compounds with Selective Activity in Voltage-Gated Sodium Channels
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Methods for Increasing N-Glycan Occupancy and Reducing Production of Hybrid N-Glycans in Pichia Pastoris Strains Lacking ALG3 Expression
Nano-Suspension Process
MACROCYCLES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
Isoxazolopyridine Orexin Receptor Antagonists
Piperidinyl Alkyne Orexin Receptor Antagonists
Engineered Lower Eukaryotic Host Strains for Recombinant Protein Expression
Gamma Secretase Modulators
Process for Synthesizing a CETP Inhibitor
Aminopyrimidinones as Interleukin Receptor-Associated Kinase Inhibitors
Methods of Preparing Lyophilized Spherical-Shaped Pellets of Biological Materials
Biomarkers for Tslp Treatment
QUINOLINE CARBOXAMIDE AND QUINOLINE CARBONITRILE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE
Triazolopyridinone PDE10 Inhibitors
Hcv NS3 Protease Inhibitors
Substituted Cyclopropyl Compounds Useful as GPR119 Agonists
Method for Preparation of Aluminum Hydroxyphosphate Adjuvant
Pyrrolopyrimidines as Janus Kinase Inhiitors
Inhibitors of the Renal Outer Medullary Potassium Channel
Substituted Piperidines as HDM2 Inhibitors
Vaccines Against Clostridium Difficile Comprising Recombinant Toxins
Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Preparation and Use of Bicyclic Himbacine Derivatives as Par-1 Receptor Antagonists
Bis-Quarternary Cinchona Alkaloid Salts as Asymmetric Phase Transfer Catalysts
Process for Making Cgrp Receptor Antagonists
Thrombin Inhibitors
Imidazolyl Methyl Piperidine T-Type Calcium Channel Antagonists
Aldosterone Synthase Inhibitors
Tetrahydronaphthyridine and Related Bicyclic Compounds for Inhibition of Rorgamma Activity and the Treatment of Disease
BICYCLIC SULFONE COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Cyclic Amine Substituted Heterocyclic Cetp Inhibitors
Process for the Preparation of an Intermediate for an Orexin Receptor Antagonists
Permeable Glycosidase Inhibitors and Uses Thereof
Spirolactam Cgrp Receptor Antagonists
Process for Making Cgrp Receptor Antagonists
Aliphatic Spirolactam Cgrp Receptor Antagonists
Surface Anchored Light Chain Bait Antibody Display System
Pyridine Cgrp Receptor Antagonists
Solid Dosage Formulations of an Orexin Receptor Antagonists
Pyrazolyl Derivatives as Syk Inhibitors
Imidazolyl Analogs as Syk Inhibitors
Substituted Pyridine Spleen Tyrosine Kinase (Syk) Inhibitors
Substituted Diazine and Triazine Spleen Tyrosine Kinease (Syk) Inhibitors
Sulfonamide Derivatives and Methods of Use Thereof for Improving the Pharmacokinetics of a Drug
Mineralocorticoid Receptor Antagonists
Treating Diabetes with Dipeptidyl Peptidase-Iv Inhibitors
Treating Diabetes with Dipeptidyl Peptidase-Iv Inhibitors
Antidiabetic Tricyclic Compounds
Novel Azabenzimidazole Hexahydrofuro[3,2-B]Furan Derivatives
Novel Azabenzimidazole Tetrahydrofuran Derivatives
Novel Azabenzimidazole Tetrahydropyran Derivatives
Novel Benzimidazole Hexahydrofuro[3,2-B]Furan Derivatives
Novel Benzimidazole Tetrahydrofuran Derivatives
Novel Benzimidazole Tetrahydropyran Derivatives
4-HETEROARYL SUBSTITUTED BENZOIC ACID COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
N-ALKYLATED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
3-CYCLOHEXENYL AND CYCLOHEXYL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
3-AMINOCYCLOALKYL COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
Substituted Phenyl-Spleen Tyrosine Kinase (Syk) Inhibitors
Tricyclic Gyrase Inhibitors
Crystalline Form of a Reverse Transcriptase Inhibitor
Novel Compounds That Are Erk Inhibitors
Novel Compounds That Are Erk Inhibitors
Triazolyl Derivatives as Syk Inhibitors
Substituted Isoquinolines as CRTH2 Receptor Modulators
Tricyclic Substituted Thiadiazine Dioxide Compounds as Bace Inhibitors, Compositions and Their Use
Tricyclic Substituted Thiadiazine Dioxide Compounds as Bace Inhibitors, Compositions and Their Use
Indoline Compounds as Aldosterone Synthase Inhibitors
Inhibitors of IRAK4 Activity
Inhibitors of IRAK4 Activity
Substituted Spiropiperidinyl Compounds Useful as GPR120 Agonists
2-Pyridyloxy-3-Ester-4-Nitrile Orexin Receptor Antagonists
2'-Disubstituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
2'-Cyano Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
N-Substituted Indazole Sulfonamide Compounds with Selective Activity in Voltage-Gated Sodium Channels
Benzoxazolinone Compounds with Selective Activity in Voltage-Gated Sodium Channels
2-Pyridyloxy-3-Substituted-4-Nitrile Orexin Receptor Antagonists
Secondary Alcohol Substituted Triazoles as PDE10 Inhibitors
Cyclopropyl Imidazopyridine PDE10 Inhibitors
Cyclobutyl Benzimidazoles as Pde 10 Inhibitors
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Thrombin Inhibitors
Pyrimidine PDE10 Inhibitors
Substituted Pyridone Derivatives as PDE10 Inhibitors
2'-Alkynyl Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Immunoregulation by Anti-ILT5 Antibodies and ILT5-Binding Antibody Fragments
Substituted Imidazopyridines as HDM2 Inhibitors
Inhibitors of Hepatitis C Virus Replication
C.difficile Toxin B CROP Domain Peptides, Antibodies and Complexes Thereof
Patent:
9,181,632 →
Application:
14/479,735 →
Fused Bicyclic Oxazolidinone CETP Inhibitor
Treating Infections with Ceftolozane/Tazobactam in Subjects Having Impaired Renal Function
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Glucose-Responsive Insulin Conjugates
Piperidinone Carboxamide Indane Cgrp Receptor Antagonists
Cathepsin Cysteine Protease Inhibitors
Novel Crystalline Forms of a Dipeptidyl Peptidase-Iv Inhibitors
Methods for Treating Intrapulmonary Infections
Spiropyrrolidine Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease
Mineralocorticoid Receptor Antagonists
Inhibitors of the Renal Outer Medullary Potassium Channel
Heterocyclic Aspartyl Protease Inhibitors
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
MAMMALIAN EXPRESSION VECTOR pUHAB
Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use
Hcv NS3 Protease Inhibitors
Anti-ILT5 Antibodies and ILT5-Binding Antibody Fragments
Compositions and Methods for Treating Cancer
Inhibitors of the Renal Outer Medullary Potassium Channel
2-Pyridylamino-4-Nitrile-Piperidinyl Orexin Receptor Antagonists
Spirocyclic Sulfones as Gamma Secretase Inhibitors
Disulfide Masked Prodrug Compositions and Methods
Nucleoside Kinase Bypass Compositions and Methods
O-Glycosylated Carboxy Terminal Portion (Ctp) Peptide-Based Insulin and Insulin Analogues
Regioselective N-2 Arylation of Indazoles
Biocatalytic Transamination Process
Process for Making Reverse Transcriptase Inhibitors
Medication Injector with Near-Empty Alert
Iminothiadiazine Dioxides Containing a Thioamide, Amidine, or Amide Oxime Group as Bace Inhibitors, Compositions, and Their Use
Inhibitors of the Renal Outer Medullary Potassium Channel
Indazole Compounds as Aldosterone Synthase Inhibitors
Amino-Pyrimidine-Containing Spleen Tyrosine Kinase (Syk) Inhibitors
Factor IXa Inhibitors
Factor IXa Inhibitors
Factor IXa Inhibitors
Substituted Pyrrolopyrimidines as HDM2 Inhibitors
Process for Purifying Insulin and Analogues Thereof
4-Pyridinonetriazine Derivatives as Hiv Integrase Inhibitors
Novel Glucokinase Activator Compounds, Compositions Containing Such Compounds, and Methods of Treatment
Novel 2-Pyridinecarboxamide Derivatives, Compositions Containing Such Compounds, and Methods of Treatment
Therapeutic Thiazolidinone Compounds
Spirocyclic Cetp Inhibitors
Thiazole-Substituted Aminopyridines as Spleen Tyrosine Kinase Inhibitors
C5-Spiro Iminothiadiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
C6-Azaspiro Iminothiadiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
C5,C6 Oxacyclic-Fused Thiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
2-Pyridyloxy-4-Ester Orexin Receptor Antagonists
3-Ester-4 Substituted Orexin Receptor Antagonists
2-Pyridyloxy-3-Nitrile-4-Substituted Orexin Receptor Antagonists
Antibodies That Bind to Human Programmed Death Ligand 1 (Pd-L1)
Dual Chamber Mixing Syringes and Methods of Using Same
Glycosidase Inhibitors and Uses Thereof
Piperazine-Substituted [1,2,4]Triazolo[1,5-C]Quinazolin-5-Amine Compounds with A2A Antagonist Properties
Heterobicyclo-Substituted [1,2,4]Triazolo[1,5-C]Quinazolin-5-Amine Compounds with A2A Antagonist Properties
Posaconazole Intravenous Solution Formulations Stabilized by Substituted Beta-Cyclodextrin
4'-Substituted Nucleoside Reverse Transcriptase Inhibitors
Cell Line 3M
Mdl-1 Ligand
RORgammaT INHIBITORS
4-Fluoropiperidine Orexin Receptor Antagonists
Heterocycle-Substituted Tetracyclic Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
2,6,7,8 Substituted Purines as HDM2 Inhibitors
Btk Inhibitors
Substituted Benzamides and Substituted Pyridinecarboxamides as Btk Inhibitors
2,6,7 Substituted Purines as HDM2 Inhibitors
Tetracyclic Heterocycle Compounds and Methods of Use Thereof for the Treatment of Hepatitis C
Tetracyclic Heterocycle Compounds and Methods of Use Thereof for the Treatment of Hepatitis C
Tetracyclic Heterocycle Compounds and Methods of Use Thereof for the Treatment of Hepatitis C
Composition of Tiacumicin Compounds
Antidiabetic Bicyclic Compounds
Immobilized Transaminases and Process for Making and Using Immobilized Transaminase
Inhibitors of the Renal Outer Medullary Potassium Channel
Novel Indole Derivatives Useful as Anti-Diabetic Agents
Substituted Pyridizinone Derivatives as PDE10 Inhibitors
Immobilized Ketoreductases and Process for Making and Using Immobilized Ketoreductase
2-Pyridyloxy-4-Ether Orexin Receptor Antagonists
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
S-Imino-S-Oxo-Iminothiazine Compounds as Bace Inhibitors, Compositions, and Their Use
S-Imino-S-Oxo-Iminothiadiazine Compounds as Bace Inhibitors, Compositions, and Their Use
C2-Azaspiro Iminothiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
Inhibitors of the Renal Outer Medullary Potassium Channel
Adapted Lepidopteran Insect Cells for the Production of Recombinant Proteins
Cycloalkyl Nitrile Pyrazolo Pyridones as Janus Kinase Inhibitors
Geminally Substituted Cyanoethylpyrazolo Pyridones as Janus Kinase Inhibitors
N-(2-Cyano Heterocyclyl) Pyrazolo Pyridones as Janus Kinase Inhibitors
Acyclic Cyanoethylpyrazolo Pyridones as Janus Kinase Inhibitors
Factor XIa Inhibitors
Methods and Compositions for Treating Cancer by Identifying One or More Erk Mutations
SUBSTITUTED PYRIDO[1,2-a]PYRAZINES AS HIV INTEGRASE INHIBITORS
Hydroxy-Substituted Orexin Receptor Antagonists
Thiazole-Substituted Aminoheteroaryls as Spleen Tyrosine Kinase Inhibitors
Thiazole-Substituted Aminopyrimidines as Spleen Tyrosine Kinase Inhibitors
Alpha 7 Nicotinic Acetylcholine Receptor Modulators and Uses Thereof-Iii
Novel Compounds That Are Erk Inhibitors
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment of Diabetes
Aryl Methyl Benzoquinazolinone M1 Receptor Positive Allosteric Modulators
Immunoassay for Soluble Pd-L1
Process for Making CGRP Receptor Antagonists
Ceftolozane Antibiotic Compositions
Recombinant Subunit Dengue Virus Vaccine
Process for Preparing Chiral Dipeptidyl Peptidase-Iv Inhibitors
Imidazopyridyl Compounds as Aldosterone Synthase Inhibitors
Triazolopyridyl Compounds as Aldosterone Synthase Inhibitors
Assay for Determining Endogenous Levels of Analyte in Vivo
Fused Tricyclic Heterocyclic Compounds as Hiv Integrase Inhibitors
Imidazole Derivatives and Methods of Use Thereof for Improving the Pharmacokinetics of a Drug
Fused Tricyclic Heterocyclic Compounds as Hiv Integrase Inhibitors
Process for the Preparation of Chiral Tert-Butyl 4-((1R,2S,5R)-6-(Benzyloxy)-7-Oxo-1,6-Diazabicyclo[3.2.1]Octane-2-Carboxamido)Piperidine-1-Carboxylate Derivatives and (2S,5R)-7-Oxo-N-Piperidin-4-Yl-6-(Sulfoxy)-1,6-Diazabicyclo[3.2.1]Octane-2-Carboxamide
Cmv Neutralizing Antigen Binding Proteins
Heterocyclic Compounds and Methods of Use Thereof for the Treatment of Hepatitis C
Dengue Virus Vaccine Compositions and Methods of Use Thereof
Substituted Benzofuran Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Cyclic Phosphonate Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Oral Pharmaceutical Formulation of Omarigliptin
Bicyclic Ureas and Thiadiazolidine-1, 1-Dioxides as Cetp Inhibitors
Inhibitors of the Renal Outer Medullary Potassium Channel
Piperazine Derivatives as Hiv Protease Inhibitors
Thiazole Orexin Receptor Antagonists
Oxazole Orexin Receptor Antagonists
Preparation and Use of 7A-Amide Substituted- 6,6-Difluoro Bicyclic Himbacine Derivatives as Par-1 Receptor Antagonists
Preparation and Use of 3-Pyridyl Substituted- 6,6-Difluoro Bicyclic Himbacine Derivatives as Par-1 Receptor Antagonists
Modulation of Tumor Immunity
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Treating Cancer with a Combination of a Pd-1 Antagonist and Dinaciclib
2,2-Difluorodioxolo A2A Receptor Antagonists
Methods of Immunization with Varicella Zoster Virus Antigen
Insulin Receptor Partial Agonists
Triazolo-Pyrazinyl Derivatives Useful as Soluble Guanylate Cyclase Activators
Forms of R)-3-(4-(2-(2-Methyltetrazol-5-Yl)Pyridin-5-Yl)-3-Fluorophenyl)-5-Hydroxymethyl Oxazolidin-2-One Dihydrogen Phosphate
Aminotetrahydropyrans as Dipeptidyl Peptidase-Iv Inhibitors for the Treatment or Prevention of Diabetes
Non-Nucleoside Reverse Transcriptase Inhibitors
C5-Spiro Iminothiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
Tricyclic Gyrase Inhibitors
Formulations for Cgrp Receptor Antagonists
Application:
15/021,471 →
Publication:
US 2016/0220552
Antidiabetic Tricyclic Compounds
TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
Substituted Quinolizine Derivatives Useful as Hiv Integrase Inhibitors
Glucose-Responsive Insulin Conjugates
Novel Pyrrolidine Derived Beta 3 Adrenergic Receptor Agonists
Cathepsin Cysteine Protease Inhibitors
3,3'-Disubstituted Indolines as Inhibitors of Cholesterol Ester Transfer Protein
Method of Obtaining Thermostable Dried Vaccine Formulations
Method of Microwave Vacuum Drying Spherical-Shaped Pellets of Biological Materials
Thermostable Respiratory Synctial Virus (Rsv) Vaccine Compositions
Methods and Intermediates for Preparing Macrolactams
Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds and Methods of Use
Inhibitors of the Renal Outer Medullary Potassium Channel
Process for Preparing Tetracyclic Heterocycle Compounds
Pseudopolymorphs of an Hcv NS5A Inhibitor and Uses Thereof
Dual Molecular Delivery of Oligonucleotides and Peptide Containing Conjugates
Peptide Containing Conjugates for Dual Molecular Delivery of Oligonucleotides
Antidiabetic Bicyclic Compounds
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Piperidine or Piperazine Linked Imidazole and Triazole Derivatives and Methods of Use Thereof for Improving the Pharmacokinetics of a Drug
Aryl Linked Imidazole and Triazole Derivatives and Methods of Use Thereof for Improving the Pharmacokinetics of a Drug
Method for Preparing Crystalline Insulin
Bicycloamine-Substituted-N-Benzenesulfonamide Compounds with Selective Activity in Voltage-Gated Sodium Channels
Antidiabetic Substituted Heteroaryl Compounds
Quinoline Carboxamide and Quinoline Carbonitrile Derivatives as mGluR2-Negative Allosteric Modulators, Compositions, and Their Use
Quinoline Carboxamide and Quinoline Carbonitrile Derivatives as mGluR2-Negative Allosteric Modulators, Compositions, and Their Use
Ceftolozane-Tazobactam Pharmaceutical Compositions
Process for Making Reverse Transcriptase Inhibitors
Gamma Secretase Modulators
Inhibitors of the Renal Outer Medullary Potassim Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Process for Making Substituted Quinazoline Compounds
Immunohistochemical Proximity Assay for Pd-1 Positive Cells and Pd-Ligand Positive Cells in Tumor Tissue
2-Pyridyloxy-3-Ester-4-Ether Orexin Receptor Antagonists
2-Pyridyloxy-4-Methyl Orexin Receptor Antagonists
Soluble Guanylate Cyclase Activators
Soluble Guanylate Cyclase Activators
2-ACYLAMIDOMETHYL AND SULFONYLAMIDOMETHYL BENZOXAZINE CARBAMATES FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Carbamate Benzoxazine Propionic Acids and Acid Derivatives for Modulation of Rorgamma Activity and the Treatment of Disease
TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Erk Inhibitors
Iminothiadiazepane Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Fused Bicyclic Isoxazolines as Inhibitors of Cholesterol Ester Transfer Protein
Hiv Protease Inhibitors
Isoquinoline Derivatives as MGAT2 Inhibitors
Fused Tetracyclic Heterocyclic Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
C-6 Spirocarbocyclic Iminothiadiazine Dioxides as BACE Inhibitors, Compositions, and Their Use
Hiv Protease Inhibitors
Thiazole-Substituted Aminoheteroaryls as Spleen Tyrosine Kinase Inhibitors
Btk Inhibitors
Btk Inhibitors
Spirocyclic Hetercycle Compounds Useful as Hiv Integrase Inhibitors
Thiazole-Substituted Aminoheteroaryls as Spleen Tyrosine Kinase Inhibitors
Thiazole-Substituted Aminoheteroaryls as Spleen Tyrosine Kinase Inhibitors
Thioether-Piperidinyl Orexin Receptor Antagonists
2-Amino-3-Ester-Pyridyl Orexin Receptor Antagonists
Piperidinyloxy Lactone Orexin Receptor Antagonists
Diazepane Orexin Receptor Antagonists
Inhibitors of the Renal Outer Medullary Potassium Channel
Pyrimidone Carboxamide Compounds as PDE2 Inhibitors
Metallo-Beta-Lactamase Inhibitors
Antidiabetic Compounds
Prefilled Disposable Injection Device
Tablet Formulation for Cgrp Active Compounds
Cathepsin Cysteine Protease Inhibitors
FACTOR XIa INHIBITORS
FACTOR XIa INHIBITORS
FACTOR XIa INHIBITORS
Method for Treating Cancer
Lipid Nanoparticle Vaccine Adjuvants and Antigen Delivery Systems
Hiv Protease Inhibitors
Purifying Insulin Using Cation Exchange and Reverse Phase Chromatography in the Presence of an Organic Modifier and Elevated Temperature
Piperazine Derivatives as Hiv Protease Inhibitors
2-Pyrazine Carboxamides as Spleen Tyrosine Kinase Inhibitors
Polymeric Nanoparticles and Methods of Making and Using Same
Trka Kinase Inhibitors, Compositions and Methods Thereof
Trka Kinase Inhibitors, Compositions and Methods Thereof
Trka Kinase Inhibitors, Compositions and Methods Thereof
Trka Kinase Inhibitors, Compositions and Methods Thereof
Pyrazolopyridyl Compounds as Aldosterone Synthase Inhibitors
Surface, Anchored Fc-Bait Antibody Display System
Glucose-Responsive Insulin Conjugates
Indoline Compounds as Aldosterone Synthase Inhibitors
Antiviral Beta-Amino Acid Ester Phosphodiamide Compounds
Cyclic Di-Nucleotide Compounds as Sting Agonists
CRZ1 Mutant Fungal Cells
Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Btk Inhibitors
Gyrase Inhibitors
Anti-Pembrolizumab Antibodies
Fused Tricyclic Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Prodrugs of Hiv Reverse Transcriptase Inhibitors
Phosphate Based Linkers for Intracellular Delivery of Drug Conjugates
Sitagliptin Tannate Complex
FACTOR IXa INHIBITORS
Factor Ixa Inhibitors
Pharmaceutical Salts of an Orexin Receptor Antagonist
FACTOR XIa INHIBITORS
Beta-Tetrazolyl-Propionic Acids as Metallo-Beta-Lactamase Inhibitors
Antidiabetic Tricyclic Compounds
FACTOR XIa INHIBITORS
Prefilled Disposable Injection Device
C2-Carbocyclic Iminothiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
Imidazo-Pyrazine Derivatives Useful as Soluble Guanylate Cyclase Activators
Pyrrolo[2,3-C]Pyridines as Imaging Agents for Neurofibrillary
Alpha-7 Nicotinic Acetylcholine Receptor Modulators and Uses Thereof
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Reactions of Thiadiazolyl-Oximinoacetic Acid Derivative Compounds
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Process for Preparing Chiral Dipeptidyl Peptidase-Iv Inhibitors
Chromatography Process for Purification of Insulin and Insulin Analogs
[5,6]-Fused Bicyclic Antidiabetic Compounds
Antidiabetic Bicyclic Compounds
Antidiabetic Bicyclic Compounds
[7,6]-Fused Bicyclic Antidiabetic Compounds
Monocyclic Isoxazolines as Inhibitors of Cholesterol Ester Transfer Protein
Factor XIa Inhibitors
Factor XIa Inhibitors
FACTOR XIa INHIBITORS
Antibody Neutralizing Human Respiratory Syncytial Virus
PD1/CTLA4 Binders
CTLA4 Binders
PD1 and/or LAG3 Binders
HYDROXYALKYLAMINE- and HYDROXYCYCLOALKYLAMINE-SUBSTITUTED DIAMINE-ARYLSULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS
Hpv Vaccine Formulations Comprising Aluminum Adjuvant and Methods of Producing Same
Soluble Guanylate Cyclase Stimulators
6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridin-5-One Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Anti-Coagulation Factor Xi Antibodies
Regioselective N-2 Arylation of Indazoles
Heterobicyclo-Substituted [1,2,4]Triazolo[1,5-C]Quinazolin-5-Amine Compounds with A2A Antagonist Properties
Process for Making Chloro-Substituted Nucleoside Phosphoramidate Compounds
Methods for the Treatment and Prophylaxis of Hiv and Aids
Alpha-7 Nicotinic Acetylcholine Receptor Modulators and Uses Thereof-I
Forms of R)-3-(4-(2-(2-Methyltetrazol-5-Yl)Pyridin-5-Yl)-3-Fluorophenyl)-5-Hydroxymethyl Oxazolidin-2-One Dihydrogen Phosphate
Allosteric Modulators of Nicotinic Acetylcholine Receptors
RORgammaT INHIBITORS
Anti-LAG3 Antibodies and Antigen-Binding Fragments
Solid Pharmaceutical Compositions Containing An Integrase Inhibitor
Methods of Treating Diabetes by Administering a Glucagon Receptor Antagonist in Combination with a Cholesterol Absorption Inhibitor
Glycan-Based Antibody-Drug Conjugates
Novel Crystalline Forms of a Bace Inhibitor, Compositions, and Their Use
Intermediates in the Synthesis of Cephalosporin Compounds
Substituted Phosphoramidate Compounds and Uses Thereof
Synthesis of Cephalosporin Compounds
Salt Forms of Ceftolozane
Pharmaceutical Compound
Method for Preparing Crystalline Insulin or Insulin Analog Compositions
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE
Compounds Inhibiting Leucine-Rich Repeat Kinase Enzyme Activity
Tetrahydroisoquinoline Derivatives Useful as Inhibitors of Diacylglyceride O-Acyltransferase 2
Tetrahydroisoquinoline Derivatives Useful as Inhibitors of Diacylglyceride O-Acyltransferase 2
Isoquinoline Derivatives Useful as Inhibitors of Diacylglyceride O-Acyltransferase 2
S-Imino-S-Oxo Iminothiazine Compounds as Bace Inhibitors, Compositions, and Their Use
Diazine-Fused Amidines as Bace Inhibitors, Compositions, and Their Use
Inhibitors of Hif Prolyl Hydroxylase
Inhibitors of Hif Prolyl Hydroxylase
Inhibitors of Hif Prolyl Hydroxylase
Novel Crystalline Forms of a Bace Inhibitor, Compositions, and Their Use
Inhibitors of IRAK4 Activity
Inhibitors of IRAK4 Activity
Inhibitors of IRAK4 Activity
Inhibitors of IRAK4 Activity
C5-C6-Fused Tricyclic Iminothiadiazine Dioxide Compounds as Bace Inhibitors, Compositions, and Their Use
Nargenicin Compounds and Uses Thereof as Antibacterial Agents
Co-Agonists of the Glucagon and Glp-1 Receptors
Ethyl N-Boc Piperidinyl Pyrazolo Pyridones as Janus Kinase Inhibitors
Process for Making Nucleoside Phosphoramidate Compounds
Oxazole Orexin Receptor Antagonists
Piperidine Oxadiazole and Thiadiazole Orexin Receptor Antagonists
Piperidine Isoxazole and Isothiazole Orexin Receptor Antagonists
Pyrazole, Triazole and Tetrazole Orexin Receptor Antagonists
Pyrazole Orexin Receptor Antagonists
Sglt-2 Inhibitors for Treating Metabolic Disorders in Patients with Renal Impairment or Chronic Kidney Disease
Process for Preparing Substituted Indole Compounds
Aminopyrazine Compounds with A2A Antagonist Properties
Process for Producing Recombinant Trypsin
Process for Refolding Recombinant Chymotrypsin
Recombinant Expression of Chlamydia Momp Antigen
C5-C6-Oxacyclic Fused Iminopyrimidinone Compounds as Bace Inhibitors, Compositions, and Their Use
5,5-Bicyclic Oxazole Orexin Receptor Antagonists
Methyl Diazepane Orexin Receptor Antagonists
Bridged Diazepane Orexin Receptor Antagonists
Hydroxmethyl Piperidine Orexin Receptor Antagonists
Methyl Oxazole Orexin Receptor Antagonists
Erk Inhibitors
Erk Inhibitors
6,5-Bicyclic Octahydropyrrolopyridine Orexin Receptor Antagonists
Heteroaryl Orexin Receptor Antagonists
Novel Tricyclic Compounds as Inhibitors of Mutant Idh Enzymes
Novel Tricyclic Compounds as Inhibitors of Mutant Idh Enzymes
Novel Tricyclic Compounds as Inhibitors of Mutant Idh Enzymes
Ethyldiamine Orexin Receptor Antagonists
Formulation Inhibiting Effects of Low Acid Environment
Process for the Preparation of Tert-Butyl 4-((2S,5R)-6-(Benzyloxy)-7-Oxo-1,6-Diazabicyclo[3.2.1]Octane-2-Carboxamido)Piperidine-1-Carboxylate and Analogs Thereof
Spirocyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Spirocyclic Heterocyclic Compounds Useful As HIV Integrase Inhibitors
Factor IXa Inhibitors
Pyrrolidine Orexin Receptor Antagonists
Amidoethyl Azole Orexin Receptor Antagonists
Fused Heteroaryl Derivatives as Orexin Receptor Antagonists
Dengue Virus Vaccine Compositions and Methods of Use Thereof
(S)-N-(3-(6-Isopropoxypyridin-3-Yl)-1H-Indazol-5-Yl)-1-(2-(4-(4-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)-3,6-Dihydropyridin-1(2H)-Yl)-2-Oxoethyl)-3-(Methylthio)Pyrrolidine-3-Carboxamide Compositions for Pharmaceutical Preparations
(S)-N-(3-(6-Isopropoxypyridin-3-Yl)-1H-Indazol-5-Yl)-1-(2-(4-(4-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)-3,6-Dihydropyridin-1(2H)-Yl)-2-Oxoethyl)-3-(Methylthio)Pyrrolidine-3-Carboxamide Compositions for Pharmaceutical Preparations
Thiadiazolyl - Oximinoacetic Acid Derivative Compounds
Pyrazolyl Carboxylic Acid and Pyrazolyl Urea Derivative Compounds
Benzamide Imidazopyrazine Btk Inhibitors
Tertiary Alcohol Imidazopyrazine Btk Inhibitors
SUBSTITUTED IMIDAZO[1,5-a]PYRAZINES AS BTK INHIBITORS
Btk Inhibitors
Btk Inhibitors
Synthesis of Cephalosporin Compounds
FACTOR XIa INHIBITORS
Iminothiadiazine Dioxides Bearing an Amine-Linked Substituent as Bace Inhibitors, Compositions, and Their Use
Inhibitors of the Renal Outer Medullary Potassium Channel
Inhibitors of the Renal Outer Medullary Potassium Channel
Aminoquinazoline Compounds as A2A Antagonist
SUBSTITUTED PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
Factor IXa Inhibitors
Crystals of Anti-Human Pd-1 Monoclonal Antibodies
Triazolyl Pyrimidinone Compounds as PDE2 Inhibitors
Process for Preparing Recombinant Insulin Using Microfiltration
Carboxamide Inhibitors of IRAK4 Activity
Pyrazolopyrimidine Inhibitors of IRAK4 Activity
Pyrrolopyridazine Inhibitors of IRAK4 Activity
Pyrrolotriazine Inhibitors of IRAK4 Activity
Thienopyrazine Inhibitors of IRAK4 Activity
Pyrazolyl Pyrimidinone Compounds as PDE2 Inhibitors
Phosphate Substituted Quinolizine Derivatives Useful as Hiv Integrase Inhibitors
Prefilled Disposable Injection Device
Trka Kinase Inhibitors, Compositions and Methods Thereof
Process for Making Phosphoramidate Protected Nucleoside Compounds
Indazole and Azaindazole Btk Inhibitors
Blood-Based Biomarkers of Tumor Sensitivity to Pd-1 Antagonists
FACTOR XIa INHIBITORS
Heteroaryl-Pyrimidinone Compounds as PDE2 Inhibitors
Pyrimidinone Amide Compounds as PDE2 Inhibitors
6-Alkyl Dihydropyrazolopyrimidinone Compounds as PDE2 Inhibitors
Fused Tricyclic Heterocyclic Compounds Useful For Treating HIV Infection
Substituted Imidazo[1,2-a]Pyrazines as Soluble Guanylate Cyclase Activators
Imidazo-Pyrazinyl Derivatives Useful as Soluble Guanylate Cyclase Activators
Dihydropyrazolopyrimidinone Compounds as PDE2 Inhibitors
Sustained Release Formulation and Tablets Prepared Therefrom
Process for Preparing Substituted Tetracyclic Heterocycle Compounds
Substituted Pyrazolo/Imidazolo Bicyclic Compounds as PDE2 Inhibitors
Substituted Triazolo Bicyclic Compounds as PDE2 Inhibitors
Tetrahydronaphthyridine and Related Bicyclic Compounds for Inhibition of Rorgamma Activity and the Treatment of Disease
Non-Nucleoside Reverse Transcriptase Inhibitors
Anti-Coagulation Factor Xi Antibodies
Anti-Gitr Antibodies
Methods for Treating Intrapulmonary Infections
Tricyclic Gyrase Inhibitors
4-Heteroaryl Substituted Benzoic Acid Compounds as Rorgammat Inhibitors and Uses Thereof
Novel Compounds That Are Erk Inhibitors
Biocatalytic Transamination Process
FACTOR XIa INHIBITORS
Immunohistochemical Assay for Detecting Expression of Programmed Death Ligand 1 (Pd-L1) in Tumor Tissue
CHROMANE, ISOCHROMANE AND DIHYDROISOBENZOFURAN DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE
Preparation and Use of 7A-Heterocycle Substituted- 6,6-Difluoro Bicyclic Himbacine Derivatives as Par-1 Receptor Antagonists
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS
Pyrrolo[2,3-C]Pyridines as Imaging Agents for Neurofibrilary Tangles
Substituted Quinolizine Derivatives Useful as Hiv Integrase Inhibitors
Allosteric Modulators of Nicotinic Acetylcholine Receptors
TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Antidiabetic Bicyclic Compounds
Lyosphere Critical Reagent Kit
Application:
15/734,346 →
Publication:
US 2021/0223262
Bicyclic Heterocyclic Compounds as PDE2 Inhibitors
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Metallo-Beta-Lactamase Inhibitors
Metallo-Beta-Lactamase Inhibitors
Substituted Aminoquinazoline Compounds as A2A Antagonist
Substituted Bicyclic Fused Ring Compounds as Indoleamine-2,3-Dioxygenase Inhibitors
Substituted Quinolinones as PDE9 Inhibitors
Phenyl-Cyanoquinolinone PDE9 Inhibitors
Oxy-Cyanoquinolinone PDE9 Inhibitors
Genetic Markers Associated with Response to CRTH2 Receptor Antagonists
Anti-Tigit Antibodies
Cyclic Di-Nucleotide Compounds as Sting Agonists
A Process for Obtaining Insulin with Correctly Formed Disulfide Bonds
Long-Acting Co-Agonists of the Glucagon and Glp-1 Receptors
Substituted 1H-Indole-2-Carboxamide Compounds as Indoleamine-2,3-Dioxygenase Inhibitors
Antibody That Binds to Human Programmed Death Ligand 2 (Pd-L2) and Uses Thereof
4'-Substituted Nucleoside Reverse Transcriptase Inhibitors and Preparations Thereof
Process for Making M1 Receptor Positive Allosteric Modulators
Antibody Peptide Conjugates That Have Agonist Activity at Both the Glucagon and Glucagon-Like Peptide 1 Receptors
Antibody Drug Conjugate for Anti-Inflammatory Applications
Aryl Acylsulfonamides as BLT1 Antagonists
Process for Preparing Formulations for Gastrointestinal-Targeted Therapies
Aryl Acylsulfonamides as BLT1 Antagonists
Aryl Sulfonamides as BLT1 Antagonists
Novel Tricyclic Compounds as Inhibitors of Mutant Idh Enzymes
SUBSTITUTED BICYCLIC PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
SUBSTITUTED INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
HETEROARYL SUBSTITUTED BENZOIC ACIDS AS RORgammaT INHIBITORS AND USES THEREOF
Macrocyclic Spirocarbamate Derivatives as Factor Xia Inhibitors, Pharmaceutically Acceptable Compositions and Their Use
Factor Xia Inhibitors
Cyanopyridine Derivatives as Liver X Receptor Beta Agonists, Compositions, and Their Use
Co-Agonists of the Glucagon and Glp-1 Receptors
Spirocyclic Pyridotriazine Derivatives Useful As HIV Integrase Inhibitors
Amido-Substituted Pyridotriazine Derivatives Useful as Hiv Integrase Inhibitors
Metering Injector for Delivering Liquid, and Method of Using Same
Novel Processes for Making Substituted Quinazoline Compounds Using Hydrogen Bonding Catalysts
FACTOR XIa INHIBITORS
Pharmaceutical Compositions Containing Doravirine, Tenofovir Disoproxil Fumarate and Lamivudine
Homobispiperidinyl Derivatives as Liver X Receptor Beta Agonists, Compositions and Their Use
C5-C6-Carbocyclic Fused Iminothiadiazine Dioxides as Bace Inhibitors, Compositions, and Their Use
Antiviral Phosphodiamide Prodrugs of Tenofovir
Factor XIa Inhibitors
Process for Making Tetracyclic Heterocycle Compounds
Aminopyrazine Compounds with A2A Antagonist Properties
Anti-Tigit Antibodies
Tetracyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Process for Preparing Chiral Dipeptidyl Peptidase-Iv Inhibitors
Ceftolozane Antibiotic Compositions
Intermediates for Preparing Cgrp Receptor Antagonists
Antiviral Aliphatic Ester Prodrugs of Tenofovir
Surface Anchored Light Chain Bait Antibody Display System
Cyclic Di-Nucleotide Compounds as Sting Agonists
Cyclic Di-Nucleotide Compounds as Sting Agonists
Humanized Antibody for Treating or Preventing Cognitive Disorders, Process for Producing the Same, and Agent for Treating or Preventing Cognitive Disorders Using the Same
Nargenicin Compounds and Uses Thereof as Antibacterial Agents
7-Aminocephem Derivative Compounds
Modulation of Tumor Immunity
Antibody Neutralizing Human Respiratory Syncytial Virus
Antibody Neutralizing Human Respiratory Syncytial Virus
Antibody Neutralizing Human Respiratory Syncytial Virus
Anti-ILT4 Antibodies and Antigen-Binding Fragments
Forms of R)-3-(4-(2-(2-Methyltetrazol-5-Yl)Pyridin-5-Yl)-3-Fluorophenyl)-5-Hydroxymethyl Oxazolidin-2-One Dihydrogen Phosphate
Forms of R)-3-(4-(2-(2-Methyltetrazol-5-Yl)Pyridin-5-Yl)-3-Fluorophenyl)-5-Hydroxymethyl Oxazolidin-2-One Dihydrogen Phosphate
Dual Molecular Delivery of Oligonucleotides and Peptide Containing Conjugates
Processes for the Preparation of a Bace Inhibitor
SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS PDE9 INHIBITORS
Insulin Receptor Partial Agonists
Method for Preparing Antibodies Having Improved Properties
Soluble Guanylate Cyclase Stimulators
Novel Compounds That Are Erk Inhibitors
Solid Dosage Formulations of an Orexin Receptor Antagonist
Spirocyclic Quinolizine Derivatives Useful as HIV Integrase Inhibitors
Novel Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Antiviral Oxime Phosphoramide Compounds
DIAMINO-ALKYLAMINO-Linked ARYLSULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS
Substituted Piperidinyl Thiazolyl Acetamides as Glycosidase Inhibitors and Uses Thereof
Anti-LAG3 Antibodies and Antigen-Binding Fragments
3-(1H-Pyrazol-4-Yl)Pyridine Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Thermally Stable Rotavirus Vaccine Formulations and Methods of Use Thereof
Prefilled Disposable Injection Device
Phosphonate Linkers and Their Use to Facilitate Cellular Retention of Compounds
Methods of Preparing Hydroxylamine Derivatives Useful in the Preparation of Anti-Infective Agents
C5-C6-Oxacyclic Fused Iminothiadiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use
Bicyclic Aryl Monobactam Compounds and Methods of Use Thereof for the Treatment of Bacterial Infections
C5-C6-Oxacyclic Fused Iminothiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use
In Silico Process for Selecting Protein Formulation Excipients
Antidiabetic Bicyclic Compounds
N1-Phenylpropane-1,2-Diamine Compounds with Selective Activity in Voltage-Gated Sodium Channels
Novel Substituted Imidazopyridine Compounds as Inhibitors of Indoleamine 2,3-Dioxygenase and/or Tryptophan-2,3-Dioxygenase
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Insulin Dimer-Incretin Conjugates
Hepatitis C Virus Inhibitors
Cmv Neutralizing Antigen Binding Proteins
Insulin Receptor Partial Agonists and Glp-1 Analogues
Anti-Coagulation Factor Xi Antibodies
Formulations for Cgrp Receptor Antagonists
Application:
16/125,924 →
Publication:
US 2019/0070161
Surface, Anchored Fc-Bait Antibody Display System
Chewable Dosage Forms Containing Sitagliptin and Metformin
Surface Display of Whole Antibodies in Eukaryotes
6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridin-5-One Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Tablet Formulation for Cgrp Active Compounds
Application:
16/178,641 →
Publication:
US 2019/0209478
Synthesis of Cephalosporin Compounds
Novel Substituted Biaryl Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Insulin Receptor Partial Agonists
Compositions Comprising Streptococcus Pneumoniae Polysaccharide-Protein Conjugates and Methods of Use Thereof
Anti-LAG3 Antibodies and Antigen-Binding Fragments
Anti-LAG3 Antibodies and Antigen-Binding Fragments
Carbocyclic Nucleoside Reverse Transcriptase Inhibitors
Anti-LAG3 Antibodies and Antigen-Binding Fragments
Sglt-2 Inhibitors for Treating Metabolic Disorders in Patients with Renal Impairment or Chronic Kidney Disease
Metallo-Beta-Lactamase Inhibitors
Process for Making Chloro-substituted Nucleoside Phosphoramidate Compounds
Anti-Pd-1/LAG3 Bispecific Antibodies
TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE
Intermediates in the Synthesis of Cephalosporin Compounds
Process for Preparing Beta 3 Agonists and Intermediates
Insulin Receptor Partial Agonists
Fused Pyrazine Derivatives Useful as Soluble Guanylate Cyclase Stimulators
Methods for Using Triazolo-Pyrazinyl Soluble Guanylate Cyclase Activators in Fibrotic Disorders
Solid Forms of Ceftolozane and Processes for Preparing
3-Aryl- Heteroaryl Substituted 5-Trifluoromethyl Oxadiazoles as Histonedeacetylase 6 (HDAC6) Inhibitors
Cyclic Phosphate Substituted Nucleoside Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Compounds Useful for Altering the Levels of Bile Acids for the Treatment of Diabetes and Cardiometabolc Disease
Compounds Useful for Altering the Levels of Bile Acids for the Treatment of Diabetes and Cardiometabolc Disease
Heterocycle-Substituted Tetracyclic Compounds and Methods of Use Thereof for the Treatment of Viral Diseases
Chromane-Substituted Tetracyclic Compounds and Uses Thereof for the Treatment of Viral Diseases
Novel Substituted N'-Hydroxycarbamimidoyl-1,2,5-Oxadiazole Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Antiviral Prodrugs of Tenofovir
Process for Preparing Beta-Lactamase Inhibitor Hydroxylurea Intermediates
Substituted 1-Methyl-1,2,3,4-Tetrahydroisoquinoline Molecules as PCSK9 Allosteric Binders
Patient Training Device for Use with a Safety Syringe Injector
KDM5 Inhibitors
Piperidine Derivatives as Liver X Receptor Beta Agonists, Compositions, and Their Use
Aryl and Heteroaryl Ether Derivatives as Liver X Receptor Beta Agonists, Compositions, and Their Use
N-Aryl and N-Heteroaryl Piperidine Derivatives as Liver X Receptor Beta Agonists, Compositions, and Their Use
Treating Cancer with a Combination of a Pd-1 Antagonist and an Il-27 Antagonist
Application:
16/342,283 →
Publication:
US 2019/0270802
ILT3 Ligand
Purification Process for Removal of Tyrosine Sulfation Antibody Variants; Purified Compositions
Antiviral Aryl-Amide Phosphodiamide Compounds
Substituted Bicyclic Heteroaryl Allosteric Modulators of Nicotinic Acetylcholine Receptors
Diamino-Alkylamino-Linked Arylsulfonamide Compounds with Selective Activity in Voltage-Gated Sodium Channels
Substituted 6-Membered Aryl or Heteroaryl Allosteric Modulators of Nicotinic Acetylcholine Receptors
SUBSTITUTED INDAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
Sting Agonist Compounds
CHROMANE, ISOCHROMANE AND DIHYDROISOBENZOFURAN DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE
Piperidinone Carboxamide Azaindane Cgrp Receptor Antagonists
Application:
16/396,056 →
Publication:
US 2019/0275024
Oxazolidinone Compounds and Methods of Use Thereof as Antibacterial Agents
PD1 and/or LAG3 Binders
PD1 and/or LAG3 Binders
PD1 and/or LAG3 Binders
Antibody Neutralizing Human Respiratory Syncytial Virus
Tetracyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Antidiabetic Heterocyclic Compounds
Factor XIIa Inhibitors
Factor XIIa Inhibitors
Indole Derivatives Useful as Inhibitors of Diacylglyceride O-Acyltransferase 2
Indazole Derivatives Useful as Inhibitors of Diacylglyceride O-Acyltransferase 2
Hydroxy Isoxazole Compounds Useful as GPR120 Agonists
Manually-Actuated Injection Device for High-Viscosity Drugs
Antidiabetic Spirochroman Compounds
Tricyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Heterocyclic Compounds as Hiv Protease Inhibitors
Aminopyrazoles as Janus Kinase Inhibitors
Antiviral Benzyl-Amine Phosphodiamide Compounds
6,5-Fused Heteroaryl Piperidine Ether Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
6,6-Fused Heteroaryl Piperidine Ether Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Heteroaryl Piperidine Ether Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Substituted Quinolizine Derivatives Useful as Hiv Integrase Inhibitors
Methods for Making Polysaccharide-Protein Conjugates
Novel Substituted Sulfoximine Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Enhancing Immunogenicity of Streptococcus Pneumoniae Polysaccharide-Protein Conjugates
Polysaccharide-Protein Conjugates Utilizing Diphtheria Toxin Fragment B as a Carrier
Methods for Improving Filterability of Polysaccharide-Protein Conjugate Reactions
Application:
16/487,628 →
Publication:
US 2020/0061542
Oxazolidinone Compounds and Methods of Use Thereof as Antibacterial Agents
Glucose Responsive Insulin Comprising a Tri-Valent Sugar Cluster for Treatment of Diabetes
Novel Substituted N'-Hydroxycarbamimidoyl-1,2,5-Oxadiazole Compounds as Indoleamine 2,3-Dioxygenase Ido Inhibitors
Formulation for Parenteral Administration
Addition of Nucleases Directly to Cell Culture to Facilitate Digestion and Clearance of Host Cell Nucleic Acids
Addition of Nucleases Directly to Cell Culture to Facilitate Digestion and Clearance of Host Cell Nucleic Acids
Application:
16/498,831 →
Publication:
US 2020/0392468
Compositions and Methods for Treating Cancer with a Combination of an Antagonist of Pd-1 and an Anti-CTLA4 Antibody
Application:
16/499,674 →
Publication:
US 2020/0115451
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS
BENZO[b]THIOPHENE COMPOUNDS AS STING AGONISTS
Treating Infections with Ceftolozane/Tazobactam in Subjects Having Impaired Renal Function
Purifying Insulin Using Cation Exchange and Reverse Phase Chromatography in the Presence of an Organic Modifier and Elevated Temperature
Ceftolozane Antibiotic Compositions
Anti-Lap Antibody Variants
Methods of Treating or Reducing the Risk of Cardiovascular Events and Related Diseases Using Sglt-2 Inhibitors
Drug Delivery System for the Delivery of Antiviral Agents
Hsv Antigenic Peptides and Hsv Protein Vaccines
Pharmaceutical Formulation Comprising Incretin-Insulin Conjugates
Stable Formulations of Programmed Death Receptor 1 (Pd-1) Antibodies and Methods of Use Thereof
Stable Formulations of Anti-CTLA4 Antibodies Alone and in Combination with Programmed Death Receptor 1 (Pd-1) Antibodies and Methods of Use Thereof
Application:
16/609,671 →
Publication:
US 2020/0262922
Formulations of Anti-LAG3 Antibodies and Co-Formulations of Anti-LAG3 Antibodies and Anti-Pd-1 Antibodies
Stable Formulations of Anti-Tigit Antibodies Alone and in Combination with Programmed Death Receptor 1 (Pd-1) Antibodies and Methods of Use Thereof
Application:
16/610,188 →
Publication:
US 2020/0354453
Cyclic Di-Nucleotide Compounds as Sting Agonists
Newcastle Disease Viruses and Uses Thereof
Azabicyclo[4.1.0]Heptane Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
5-(Pyridin-3-Yl)Oxazole Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
3-(1H-Pyrazol-4-Yl)Pyridine Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
3-(1H-Pyrazol-4-Yl)Pyridine Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
A Novel Crystalline Form of a Bace Inhibitor, Compositions, and Use
Substituted Phenyl Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Substituted Pyridinyl Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Metallo-Beta-Lactamase Inhibitors and Methods of Use Thereof
Combinations of PD-1 Antagonists and Benzo[b]thiophene STING Agonists for Cancer Treatment
Benzo[b]thiophene STING Agonists for Cancer Treatment
Methods for Preparing Stabilized Amorphous Drug Formulations Using Acoustic Fusion
Long-Acting Co-Agonists of the Glucagon and Glp-1 Receptors
Compounds for Reducing the Viscosity of Biological Formulations
Application:
16/644,107 →
Publication:
US 2020/0206350
Pneumococcal Polysaccharides and Their Use in Immunogenic Polysaccharide-Carrier Protein Conjugates
Pneumococcal Polysaccharides and Their Use in Immunogenic Polysaccharide-Carrier Protein Conjugates
Heteroaryl Allosteric Modulators of Nicotinic Acetylcholine Receptors
Compositions and Methods for Treating Cancer with a Combination of Programmed Death Receptor (Pd-1) Antibodies and a CXCR2 Antagonist
Chromane Monobactam Compounds for the Treatment of Bacterial Infections
Sglt-2 Inhibitors for Treating Metabolic Disorders in Patients with Renal Impairment or Chronic Kidney Disease
SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINES AS PDE9 INHIBITORS
3-(1H-Pyrazol-4-Yl)Pyridine Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
9-Substituted Amino Triazolo Quinazoline Derivatives as Adenosine Receptor Antagonists, Pharmaceutical Compositions and Their Use
CTLA4 Binders
Methods for Treating Cancer with a WEE1 Inhibitor
Inclusion Complexes of an Hcv NS5B Inhibitor and Uses Thereof
Methods for the Treatment and Prophylaxis of Hiv and Aids
Compositions Comprising Streptococcus Pneumoniae Polysaccharide-Protein Conjugates and Methods of Use Thereof
Anti-CD27 Antibodies
Application:
16/724,984 →
Publication:
US 2020/0131272
Humanized Antibody for Treating or Preventing Cognitive Disorders, Process for Producing the Same, and Agent for Treating or Preventing Cognitive Disorders Using the Same
Novel Substituted Cyclobutylbenzene Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Novel Substituted Phenyloxetane and Phenyltetrahydrofuran Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Novel Substituted Cyclobutylpyridine and Cyclobutylpyrimidine Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Indazolyl-Spiro[2.2]Pentane-Carbonitrile Derivatives as LRRK2 Inhibitors, Pharmaceutical Compositions, and Uses Thereof
Indazolyl-Spiro[2.3]Hexane-Carbonitrile Derivatives as LRRK2 Inhibitors, Pharmaceutical Compositions, and Uses Thereof
Novel Substituted Tetrahydroquinolin Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Adjuvanted Vaccines
Application:
16/759,167 →
Publication:
US 2020/0325020
Stable Formulations of Cytomegalovirus
Application:
16/760,571 →
Publication:
US 2021/0299247
Novel Substituted Biaryl Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
PRMT5 Inhibitors
PRMT5 Inhibitors
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
Purine Inhibitors of Human Phosphatidylinositol 3-Kinase Delta
SUBSTITUTED IMIDAZO[1,2-c]QUINAZOLINES AS A2A ANTAGONISTS
Formulations of Dengue Virus Vaccine Compositions
Application:
16/769,837 →
Publication:
US 2020/0390877
Cyclic Di-Nucleotide Compounds as Sting Agonists
Conjugate Based Systems for Controlled Insulin Delivery
Pharmaceutical Compositions of Tedizolid Phosphate
5-Alkyl Pyrrolidine Orexin Receptor Agonists
(S)-N-(3-6-Isopropoxypyridin-3-3YL)-1H-Indazol-5-Yl)-1-(2-(4-4(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)-3,6-Dihydropyridin-1(2H-Yl)-2-Oxoethyl)-3(Methylthio)Pyrrolidine-3-Carboxamide Compositions for Pharmaceutical Preparations
Pharmaceutical Compositions Containing Doravirine, Tenofovir Disoproxil Fumarate and Lamivudine
Process for Making Beta 3 Agonists and Intermediates
Pharmaceutical Compositions of a Peptide
Anti-Tigit Antibodies
Novel Substituted Biaryl Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
C5-C6-Oxacyclic Fused Iminothiazine Dioxide Compounds Bearing an Ether Linker as BACE Inhibitors, Compositions, and Their Use
Inhibitors of Hepatitis C Virus Replication
Combination Method for Treatment of Cancer
Application:
16/861,660 →
Publication:
US 2020/0297788
Anti-Coagulation Factor Xi Antibodies
Anti-Coagulation Factor Xi Antibodies
Anti-Coagulation Factor Xi Antibodies
Anti-Coagulation Factor Xi Antibodies
Synthesis of Cephalosporin Compounds
(S)-N-(3-(6-Isopropoxypyridin-3-Yl)-1H-Indazol-5-Yl)-1-(2-(4-(4-(1-Methyl-1H-1,2,4-Triazol-3-Yl)Phenyl)-3,6-Dihydropyridin-1(2H)-Yl)-2-Oxoethyl)-3-(Methylthio)Pyrrolidine-3-Carboxamide Compositions for Pharmaceutical Preparations
Cyclic Di-Nucleotide Compounds as Sting Agonists
Patent:
11,453,697 →
Application:
16/904,888 →
Biaryl Monobactam Compounds and Methods of Use Thereof for the Treatment of Bacterial Infections
Substituted Tetrahydroisoquinoline Compounds Useful as GPR120 Agonists
Anti-Tigit Antibodies
Stabilized Rsv F Proteins and Uses Thereof
Anti-Pd-1 Antibodies
Methods for Treating Cancer or Infection Using a Combination of an Anti-Pd-1 Antibody, an Anti-LAG3 Antibody, and an Anti-Tigit Antibody
Application:
16/966,100 →
Publication:
US 2021/0363243
Methods for Treating Cancer with Anti-Pd-1 Antibodies
Methods for Treating Cancer with Anti Pd-1 Antibodies and Anti CTLA4 Antibodies
Application:
16/966,988 →
Publication:
US 2021/0047409
Complex Molecule Substructure Identification Systems, Apparatuses and Methods
Cut Vertex Method for Identifying Complex Molecule Substructures
Arginase Inhibitors and Methods of Use
Arginase Inhibitors and Methods of Use
Tyrosine-Specific Functionalized Insulin and Insulin Analogs
Oxo-Tetrahydro-Isoquinoline Carboxylic Acids as Sting Inhibitors
Long-Acting Co-Agonists of the Glucagon and Glp-1 Receptors
Antibody Peptide Conjugates That Have Agonist Activity at Both the Glucagon and Glucagon-Like Peptide 1 Receptors
Tetracyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Phosphonate Linkers and Their Use to Facilitate Cellular Retention of Compounds
Aza-Benzothiophene Compounds as Sting Agonists
Azide Insulin Analogues
Application:
17/045,197 →
Publication:
US 2021/0163568
Scalable Chromatography Process for Purification of Human Cytomegalovirus
Novel [1.1.1] Bicyclo Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Novel Substituted Rig-I Agonists: Compositions and Methods Thereof
Patent:
11,542,505 →
Application:
17/047,271 →
Tricyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Application:
17/048,811 →
Publication:
US 2021/0115044
Process for Synthesis of a Phenoxy Diaminopyrimidine Compound
Methods for Producing Streptococcus Pneumoniae Capsular Polysaccharide Carrier Protein Conjugates from Lyospheres
Methods for Producing Streptococcus Pneumoniae Capsular Polysaccharide Carrier Protein Conjugates
Application:
17/049,245 →
Publication:
US 2021/0252125
Methods for Providing a Homogenous Solution of Lyophilized Mutant Diptheria Toxin in Dimethylsulfoxide
Spiropiperidine Allosteric Modulators of Nicotinic Acetylcholine Receptors
Rapid Method to Predict Stabilities of Pharmaceutical Compositions Containing Protein Therapeutics and Non-Reducing Sugars
Application:
17/052,687 →
Publication:
US 2021/0236640
Lyophilization Bag
Application:
17/053,251 →
Publication:
US 2021/0236384
Tricyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
Novel Substituted [1.1.1] Bicyclo Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
[3.3.1] Bicyclo Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Formulations of Raltegravir
Application:
17/059,864 →
Publication:
US 2021/0290548
Processes for the Preparation of Sugammadex
Fc-Containing Polypeptides Having Improved Properties and Comprising Mutations at Positions 243 and 264 of the Fc-Region
Fused Tricyclic Heterocyclic Compounds as Hiv Integrase Inhibitors
Application:
17/081,094 →
Publication:
US 2021/0040096
Method of Microwave Vacuum Drying Spherical-Shaped Pellets of Biological Materials
Application:
17/081,484 →
Publication:
US 2021/0048247
Oxazolidinone Compounds and Methods of Use Thereof as Antibacterial Agents
Application:
17/093,833 →
Publication:
US 2021/0061777
Antibody Neutralizing Human Respiratory Syncytial Virus
Humanized Antibody for Treating or Preventing Cognitive Disorders, Process for Producing the Same, and Agent for Treating or Preventing Cognitive Disorders Using the Same
Purified Compositions of Enteroviruses and Methods of Purification with Glutathione Affinity Chromatography
Application:
17/125,002 →
Publication:
US 2021/0187049
Treating Infections with Ceftolozane/Tazobactam in Subjects Having Impaired Renal Function
Application:
17/165,758 →
Publication:
US 2022/0054460
4'-Substituted Nucleoside Reverse Transcriptase Inhibitors and Preparations Thereof
Application:
17/166,512 →
Publication:
US 2021/0154221
Hpv Vaccine
Drug Delivery System for the Delivery of Antiviral Agents
Application:
17/193,493 →
Publication:
US 2021/0186867
Substituted 6-Membered Aryl or Heteroaryl Allosteric Modulators of Nicotinic Acetylcholine Receptors
HUMAN INTERLEUKIN-2 CONJUGATES BIASED FOR THE INTERLEUKIN-2 RECEPTOR BETA GAMMAc DIMER AND CONJUGATED TO A NONPEPTIDIC, WATER-SOLUBLE POLYMER
Enzymatic Synthesis of 4'-Ethynyl Nucleoside Analogs
Hiv Drug Combination for Increasing Barrier Against Resistance
Phosphinic Amide Prodrugs of Tenofovir
Methods of Separating Host Cell Lipases from a Production Protein in Chromatographic Processes
Application:
17/261,365 →
Publication:
US 2022/0267369
Inhibitors of Histone Deacetylase Useful for the Treatment or Prevention of Hiv Infection
PRMT5 Inhibitors
PRMT5 Inhibitors
PRMT5 Inhibitors
PRMT5 Inhibitors
A Virus Neutralization Assay Utilizing Imaging Cytometry
Novel Substituted Tetrahydroquinoline Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Novel Aryloxypiperidine Pyrazole Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Combination Therapy of a Pd-1 Antagonist and LAG3 Antagonist for Treating Patients with Non-Microsatellite Instability-High or Proficient Mismatch Repair Colorectal Cancer
Application:
17/274,531 →
Publication:
US 2021/0317214
Expression Vectors for Eukaryotic Expression Systems
Novel Arylalkyl Pyrazole Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Formulations of Anti-Rsv Antibodies and Methods of Use Thereof
Factor XIa Inhibitors
3-(1H-Pyrazol-4-Yl)Pyridine Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor
Formulations of Antiviral Compounds
Application:
17/286,620 →
Publication:
US 2021/0361663
Novel Substituted Pyrazole Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Anti-Human Pd-1 Antibody Crystals and Methods of Use Thereof
Inhibitors of Histone Deacetylase Useful for the Treatment or Prevention of Hiv Infection
Dosing Regimen of Anti-Tigit Antibody for Treatment of Cancer
Application:
17/288,641 →
Publication:
US 2021/0403557
Novel Substituted Tricyclic Compounds as Indoleamine 2,3-Dioxygenase Inhibitors
Analytical Tool for Characterization of Lipid Nanoparticles
Application:
17/289,095 →
Publication:
US 2021/0388023
2-Amino-N-Heteroaryl-Nicotinamides as NAV1.8 Inhibitors
Application:
17/289,123 →
Publication:
US 2021/0387966
2-Amino-N-Phenyl-Nicotinamides as NAV1.8 Inhibitors
Dosing Regimen of Anti-LAG3 Antibody and Combination Therapy with Anti-Pd-1 Antibody for Treating Cancer
Application:
17/289,810 →
Publication:
US 2021/0347889
Stable Formulations of Programmed Death Receptor 1 (Pd-1) Antibodies and Methods of Use Thereof
Application:
17/290,816 →
Publication:
US 2021/0380694
Co-Formulations of Anti-LAG3 Antibodies and Anti-Pd-1 Antibodies
Novel Substituted Piperazine Amide Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
4-Amino or 4-Alkoxy-Substituted Aryl Sulfonamide Compounds with Selective Activity in Voltage-Gated Sodium Channels
Cell-Based Bioidentity Test for Insulin
Application:
17/299,034 →
Publication:
US 2022/0026414
Cyclic Di-Nucleotide Compounds as STING Agonists
Application:
17/299,350 →
Publication:
US 2022/0024964
Cyclic Di-Nucleotide Compounds as STING Agonists
Application:
17/299,355 →
Publication:
US 2022/0033435
Cyclic Di-Nucleotide Compounds as STING Agonists
Application:
17/299,359 →
Publication:
US 2022/0033431
Method for Identifying High Affinity Monoclonal Antibody Heavy and Light Chain Pairs from High Throughput Screens of B-Cell and Hybridoma Libraries
Application:
17/299,559 →
Publication:
US 2022/0034902
Cyclobutyl Pyrazolopyrimidine PDE9 Inhibitors
Pyrazolopyrimidine PDE9 Inhibitors
Application:
17/299,648 →
Publication:
US 2022/0017526
Compositions Comprising Streptococcus Pneumoniae Polysaccharide-Protein Conjugates and Methods of Use Thereof
Application:
17/312,442 →
Publication:
US 2022/0296695
Arginase Inhibitors and Methods of Use
Eye Wash Station Inspection Guard
Application:
17/317,993 →
Publication:
US 2021/0355664
Diacylglyceride O-Acyltransferase 2 Inhibitors
Inhibitors of Hepatitis C Virus Replication
Application:
17/324,799 →
Publication:
US 2022/0356182
Vial Holder
Application:
17/336,435 →
Publication:
US 2021/0379596
Syringe Holder
Application:
17/336,464 →
Publication:
US 2021/0379278
Anti-ILT4 Antibodies and Antigen-Binding Fragments
Anti-ILT4 Antibodies and Antigen-Binding Fragments
Surface Display of Whole Antibodies in Eukaryotes
Aryl Sulfonamides as BLT1 Antagonists
High Affinity Antibodies Targeting Tau Phosphorylated at Serine 413
Enhancing Immunogenicity of Streptococcus Pneumoniae Polysaccharide-Protein Conjugates
Application:
17/369,177 →
Publication:
US 2021/0330777
Enhancing Immunogenicity of Streptococcus Pneumoniae Polysaccharide-Protein Conjugates
Application:
17/369,230 →
Publication:
US 2021/0330778
Compositions Comprising Streptococcus Pneumoniae Polysaccharide-Protein Conjugates and Methods of Use Thereof
Genetic Markers Associated with Response to CRTH2 Receptor Antagonists
Application:
17/377,514 →
Publication:
US 2021/0348235
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Application:
17/377,924 →
Publication:
US 2022/0025042
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Application:
17/378,000 →
Publication:
US 2022/0033497
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Application:
17/378,030 →
Publication:
US 2022/0025043
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Antibodies Specific for Immunoglobulin-Like Transcript 3 (ILT3) and Uses Thereof
Anti-Pd-1/LAG3 Bispecific Antibodies
Application:
17/384,539 →
Publication:
US 2021/0363256
Anti-Pd-1/LAG3 Bispecific Antibodies
Application:
17/384,561 →
Publication:
US 2021/0371530
Insulin-Incretin Conjugates
Application:
17/386,958 →
Publication:
US 2023/0105982
Process for Preparing Beta 3 Agonists and Intermediates
Bicycloheptane Pyrrolidine Orexin Receptor Agonists
Tetrahydroquinazoline Derivatives as Selective Cytotoxic Agents
Pneumococcal Conjugate Vaccine Formulations
Application:
17/412,550 →
Publication:
US 2022/0031837
Pyrimidone Derivatives as Selective Cytotoxic Agents Against Hiv Infected Cells
Methods of Using Butyrophilin Antibodies for Treating Hiv Infection
Application:
17/415,031 →
Publication:
US 2022/0064291
Novel Crystalline Forms of an Nrtti Compound
Expression Vectors for Eukaryotic Expression Systems
Application:
17/416,286 →
Publication:
US 2022/0073945
Supplemented Serum-Containing Culture Medium for Enhanced Arpe-19 Growth and Human Cytomegalovirus Vaccine Production
Application:
17/420,177 →
Publication:
US 2022/0090005
Oxazolidinone Compounds and Methods of Use Thereof as Antibacterial Agents
Inhibitors of Histone Deacetylase Useful for the Treatment or Prevention of Hiv Infection
Pyrrolidine Orexin Receptor Agonists
Gene Expression Based Biomarker of Tumor Response to Pd-1 Antagonists
Application:
17/430,448 →
Publication:
US 2022/0112564
Anti-Cancer Combination Therapies Comprising Ctla-4 and Pd-1 Blocking Agents
Inhibitors of Histone Deacetylase Useful for the Treatment or Prevention of Hiv Infection
Stable Formulations of Cyclic Dinucleotide Sting Agonist Compounds and Methods of Use Thereof
Application:
17/441,087 →
Publication:
US 2022/0175811
Methods for Making Polysaccharide-Protein Conjugates
Anti-Lap Antibody Variants and Uses Thereof
Application:
17/465,247 →
Publication:
US 2022/0017612
Solid Dosage Formulations of an Orexin Receptor Antagonist
Prefilled Disposable Injection Device
Process for Making Beta 3 Agonists and Intermediates
Stable Formulations of Programmed Death Receptor 1 (PD-1) Antibodies and Hyaluronidase Variants and Fragments Thereof and Methods of Use Thereof
Application:
17/482,650 →
Publication:
US 2022/0089738
Process for Preparing Pharmaceutical Compositions
Manually-Actuated Injection Device for High-Viscosity Drugs
Cyclic Phosphate Substituted Nucleoside Derivatives and Methods of Use Thereof for the Treatment of Viral Diseases
Application:
17/496,215 →
Publication:
US 2022/0040214
PD1 and/or LAG3 Binders
Methods for Production of Capsular Polysaccharide Protein Conjugates from Streptococcus Pneumoniae Serotype 19F
Container System and Method for Freezing and Thawing a Liquid Product
Pneumococcal Conjugate Vaccine Formulations
Application:
17/554,354 →
Publication:
US 2022/0105169
Compositions of Programmed Death Receptor 1 (Pd-1) Antibodies and Methods of Obtaining the Compositions Thereof
Inhibitors of Histone Deacetylase-3 Useful for the Treatment of Cancer, Inflammation, Neurodegeneration Diseases and Diabetes
PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR MAKING (2S,5R)-7-OXO-N-PIPERIDIN-4-YL-6-(SULFOXY)-l,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXAMIDE
Spiropiperidine Allosteric Modulators of Nicotinic Acetylcholine Receptors
Blood Biomarker and Genetic Markers Associated with Response to CRTH2 Receptor Antagonists
Application:
17/606,232 →
Publication:
US 2022/0259656
Pyridinone Derivatives as Selective Cytotoxic Agents Against Hiv Infected Cells
Application:
17/611,448 →
Publication:
US 2022/0242847
Natriuretic Peptide Receptor a Agonists Useful for the Treatment of Cardiometabolic Diseases, Kidney Disease and Diabetes
Natriuretic Peptide Receptor a Agonists Useful for the Treatment of Cardiometabolic Diseases, Kidney Disease and Diabetes
Application:
17/611,553 →
Publication:
US 2022/0281886
Factor Xi Activation Inhibitors
Glucose-Responsive Insulin Conjugates
1-Pyrazolyl, 5-, 6- Disubstituted Indazole Derivatives as LRRK2 Inhibitors, Pharmaceutical Compositions, and Uses Thereof
An Immunogenic Serotype 35B Pneumococcal Polysaccharide-Protein Conjugate and Conjugation Process for Making the Same
Application:
17/614,865 →
Publication:
US 2022/0233674
Novel Substituted Tetrahydroquinolin Compounds as Indoleamine 2,3-Dioxygenase (Ido) Inhibitors
Hydroxypyrrolidine-Substituted Arylsulfonamide Compounds with Selective Activity in Voltage-Gated Sodium Channels
Process for Separating Antigen-Binding Polypeptide Monomers Comprising One or More Immunoglobulin Single Variable Domains from Aggregates of Said Monomers
Application:
17/617,782 →
Publication:
US 2022/0267370
Containment System for Mixing Dry Powders with Solvents During Drug Production or Processing
Application:
17/618,641 →
Publication:
US 2022/0250013
Process for the Preparation of 2-Fluoroadenine
Compounds and Methods of Use Thereof as Antibacterial Agents
Antigenic Glycoprotein E Polypeptides, Compositions, and Methods of Use Thereof
Methods and Assemblies for Preparing and Dispensing Lyospheres of Pharmaceutical Compositions
Application:
17/628,711 →
Publication:
US 2022/0265558
Glucose-Responsive Insulin Conjugates
Application:
17/629,501 →
Publication:
US 2022/0273770
Anti-Pd-1/LAG3/Tigit Trispecific Antibodies and Anti-Pd-1/LAG3 Bicpecific Antibodies
Application:
17/630,586 →
Publication:
US 2022/0251194
Heteroaryl Pyrrolidine and Piperidine Orexin Receptor Agonists
Drug Delivery System for the Delivery of Antiviral Agents
Application:
17/633,300 →
Publication:
US 2022/0362277
Antimalarial Agents
Methods and Compositions Comprising an Anti-CTLA4 Monoclonal Antibody with Reduced Host Cell Proteins and Increased Polysorbate-80 Stability
Application:
17/642,870 →
Publication:
US 2024/0115701
9-Substituted Amino Triazolo Quinazoline Derivatives as Adenosine Receptor Antagonists, Pharmaceutical Compositions and Their Use
Methods for Treatment and Prophylaxis of Hiv and Aids
Glycan-Based Antibody-Drug Conjugates
Application:
17/658,731 →
Publication:
US 2022/0242970
Anti-LAG3 Antibodies and Antigen-Binding Fragments
Tetracyclic Heterocycle Compounds Useful as Hiv Integrase Inhibitors
CHROMANE, ISOCHROMANE AND DIHYDROISOBENZOFURAN DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE
Application:
17/695,262 →
Publication:
US 2022/0218676
Method for Measuring Nucleic Acid Content in Lipid Nanoparticles Using Ultraviolet Spectrometry
Application:
17/762,210 →
Publication:
US 2022/0397570
Methods for Treating Metastatic Triple Negative Breast Cancer with Anti-Pd-1 Antibodies
Application:
17/762,215 →
Publication:
US 2022/0380469
Apparatus and Method for Monitoring and Recording Disintegration Times for Pharmaceutical Products
Biomarkers for Anti-Tigit Antibody Treatment
Application:
17/762,530 →
Publication:
US 2022/0340660
N-(Heteroaryl) Quinazolin-2-Amine Derivatives as LRRK2 Inhibitors, Pharmaceutical Compositions, and Uses Thereof
Spiropiperidine Allosteric Modulators of Nicotinic Acetylcholine Receptors
Dosing Regimen of Anti-CD27 Antibodies for Treatment of Cancer
Application:
17/772,229 →
Publication:
US 2023/0192876
ANGIOGENESIS AND mMDSC GENE EXPRESSION BASED BIOMARKER OF TUMOR RESPONSE TO PD-1 ANTAGONISTS
Application:
17/773,396 →
Publication:
US 2022/0380854
On-Line Ultra Performance Hydrophobic Interaction Chromatography for Monitoring at Least One Product Attribute
Application:
17/778,999 →
Publication:
US 2023/0018939
Autoinjector Pen
Patent:
793,547 →
Application:
29/487,569 →
Autoinjector Pen
Patent:
780,909 →
Application:
29/487,571 →
Medical Injector Pen
Patent:
777,907 →
Application:
29/500,636 →
Medical Injector Pen
Patent:
773,646 →
Application:
29/500,640 →
Medical Injector Pen
Patent:
773,647 →
Application:
29/500,644 →
Medical Injector Pen
Patent:
752,210 →
Application:
29/500,648 →
Medical Injector Device
Patent:
777,908 →
Application:
29/500,651 →
Safety Syringe
Patent:
770,612 →
Application:
29/511,829 →
Auto Injector
Patent:
774,641 →
Application:
29/545,242 →
Medical Injector Pen
Patent:
810,283 →
Application:
29/583,993 →
Medical Injector Pen
Patent:
819,199 →
Application:
29/584,086 →
Autoinjector Device
Patent:
857,192 →
Application:
29/587,440 →
Autoinjector Pen
Patent:
870,270 →
Application:
29/612,133 →
Syringes and Injectors with Capacitive Sensing Locks and Methods of Making and Using Same
Application:
63/243,350 →
C-Linked Isoquinoline Amides as LRRK2 Inhibitors, Pharmaceutical Compositions, and Uses Thereof
Application:
63/251,193 →
Tricyclic Sulfamides and Sultams
Application:
63/254,578 →
Benzoxazinone Derivatives as Selective Cytotoxic Agents
Application:
63/256,194 →
Chromane Amidine Monobactam Compounds for the Treatment of Bacterial Infections
Application:
63/280,728 →
Human Mesothelin Binders
Application:
63/288,162 →
Chromane Amidine Monobactam Compounds for the Treatment of Bacterial Infections
Application:
63/327,385 →
Related Assignments
(6)
Other recorded transfers of the patents in this record — the chain of ownership.
Merger
Aug 27, 2012
From: MERCK SHARP & DOHME CORP.
To: SCHERING CORPORATION
Reel/Frame 028850/0515 →
Change of Name
Aug 29, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028866/0511 →
Change of Name
Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →
Corrective Assignment to Correct the Assignee Address Previously Recorded at Reel: 042389 Frame: 505. Assignor(S) Hereby Confirms the Change of Name.
Feb 14, 2018
From: DENDREON PHARMACEUTICALS, INC.
To: DENDREON PHARMACEUTICALS LLC
Reel/Frame 046088/0882 →
Change of Name
Apr 7, 2022
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 059629/0507 →
Security Interest
Dec 7, 2022
From: SIO2 MEDICAL PRODUCTS, INC.
To: SALZUFER HOLDING INC., AS ADMINISTRATIVE AGENT
Reel/Frame 062094/0121 →