IP Library › Patent Application 16609671

Patent Application Utility PCT National Stage

App. No. 16/609,671 · Confirmation No. 3824

STABLE FORMULATIONS OF ANTI-CTLA4 ANTIBODIES ALONE AND IN COMBINATION WITH PROGRAMMED DEATH RECEPTOR 1 (PD-1) ANTIBODIES AND METHODS OF USE THEREOF

Inventors: Soumendu Bhattacharya, Chakravarthy Nachu Narasimhan, Manoj K. Sharma, Xiaoyu Yang, Arnab De, Rubi Burlage, Jason K. Cheung

Applicant: Merck Sharp & Dohme LLC

Abandoned -- Failure to Respond to an Office Action View Publication ↗

	Code	Description	Pages	PDF
2025-02-13	`ABN`	Abandonment	2	View
2024-12-17	`APP.FILE.REC`	Filing Receipt	4	View
2024-12-16	`WFEE`	Fee Worksheet (SB06)	1	View
2024-12-16	`WFEE`	Fee Worksheet (SB06)	1	View
2024-08-27	`TRAN.LET`	Transmittal Letter	3	View
2024-08-27	`N417.PYMT`	Electronic Fee Payment	2	View
2024-08-27	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2024-08-27	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2024-08-27	`R46C.REQ`	Request under 37CFR1.46(c) to correct, update, change applicant	2	View
2024-08-27	`ADS`	Application Data Sheet	10	View
2024-08-27	`FOR`	Foreign Reference	98	View
2024-06-11	`CTFR`	Final Rejection	9	View
2024-06-11	`SRFW`	Search information including classification, databases and other search related notes	2	View
2024-06-11	`1449`	List of References cited by applicant and considered by examiner	10	View
2024-06-11	`SRNT`	Examiner's search strategy and results	44	View
2024-05-17	`TRAN.LET`	Transmittal Letter	3	View
2024-05-17	`FOR`	Foreign Reference	17	View
2024-05-17	`FOR`	Foreign Reference	30	View
2024-05-17	`FOR`	Foreign Reference	106	View
2024-05-17	`FOR`	Foreign Reference	194	View
2024-05-17	`FOR`	Foreign Reference	69	View
2024-05-17	`N417`	Electronic Filing System Acknowledgment Receipt	11	View
2024-05-17	`FOR`	Foreign Reference	102	View
2024-05-17	`FOR`	Foreign Reference	72	View
2024-05-17	`FOR`	Foreign Reference	84	View
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2024-05-17	`FOR`	Foreign Reference	64	View
2024-05-17	`FOR`	Foreign Reference	99	View
2024-05-17	`N417.PYMT`	Electronic Fee Payment	2	View
2024-05-17	`FOR`	Foreign Reference	34	View
2024-05-17	`FOR`	Foreign Reference	77	View
2024-05-17	`REF.OTHER`	Other reference-Patent/Application/Search Documents	22	View
2024-05-17	`FOR`	Foreign Reference	92	View
2024-05-17	`FOR`	Foreign Reference	133	View
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2024-05-17	`FOR`	Foreign Reference	172	View
2024-05-17	`FOR`	Foreign Reference	127	View
2024-05-17	`FOR`	Foreign Reference	98	View
2024-05-17	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	10	View
2024-05-17	`FOR`	Foreign Reference	91	View
2024-05-17	`FOR`	Foreign Reference	136	View
2024-05-17	`FOR`	Foreign Reference	85	View
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2024-05-17	`FOR`	Foreign Reference	59	View
2024-05-17	`FOR`	Foreign Reference	78	View
2024-04-15	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	—	View
2024-04-15	`N417.PYMT`	Electronic Fee Payment	2	View
2024-04-15	`REM`	Applicant Arguments/Remarks Made in an Amendment	6	View
2024-04-15	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2024-04-15	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2024-04-15	`CLM`	Claims	3	View
2024-04-15	`WFEE`	Fee Worksheet (SB06)	1	View
2023-12-14	`CTNF`	Non-Final Rejection	8	View
2023-12-14	`SRFW`	Search information including classification, databases and other search related notes	2	View
2023-12-14	`SRNT`	Examiner's search strategy and results	22	View
2023-12-14	`SRNT`	Examiner's search strategy and results	1	View
2023-10-31	`PET.DEC.TC`	Petition decision routed to the Technology Center to act on the decision or continue prosecution	2	View
2023-09-25	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	—	View
2023-09-25	`PET.OP`	Petition for review by the Office of Petitions	4	View
2023-09-25	`RCEX`	Request for Continued Examination (RCE)	3	View
2023-09-25	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2023-09-25	`CLM`	Claims	3	View
2023-09-25	`REM`	Applicant Arguments/Remarks Made in an Amendment	6	View
2023-09-25	`PET.OP`	Petition for review by the Office of Petitions	2	View
2023-09-25	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2023-09-25	`N417.PYMT`	Electronic Fee Payment	2	View
2023-09-25	`WFEE`	Fee Worksheet (SB06)	1	View
2023-03-13	`CTFR`	Final Rejection	8	View
2023-03-13	`SRFW`	Search information including classification, databases and other search related notes	2	View
2023-03-13	`SRNT`	Examiner's search strategy and results	1	View
2023-03-13	`SRNT`	Examiner's search strategy and results	11	View
2023-03-13	`1449`	List of References cited by applicant and considered by examiner	8	View
2023-02-13	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	8	View
2023-02-13	`FOR`	Foreign Reference	30	View
2023-02-13	`FOR`	Foreign Reference	86	View
2023-02-13	`FOR`	Foreign Reference	32	View
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2023-02-13	`FOR`	Foreign Reference	172	View
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2023-02-13	`FOR`	Foreign Reference	77	View
2023-02-13	`FOR`	Foreign Reference	59	View
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2023-02-13	`FOR`	Foreign Reference	108	View
2023-02-13	`FOR`	Foreign Reference	121	View
2023-02-13	`FOR`	Foreign Reference	116	View
2023-02-13	`WFEE`	Fee Worksheet (SB06)	2	View
2023-02-13	`N417`	Electronic Filing System Acknowledgment Receipt	8	View
2023-02-13	`TRAN.LET`	Transmittal Letter	3	View
2023-01-26	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2023-01-26	`CLM`	Claims	3	View
2023-01-26	`REM`	Applicant Arguments/Remarks Made in an Amendment	7	View
2023-01-26	`WFEE`	Fee Worksheet (SB06)	2	View
2023-01-26	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2023-01-26	`REM`	Applicant Arguments/Remarks Made in an Amendment	7	View
2023-01-26	`WFEE`	Fee Worksheet (SB06)	1	View
2022-09-03	`OA.POSTCARD`	A courtesy postcard sent by USPTO to users who opt-in for e-Office Action	1	View
2022-08-26	`CTNF`	Non-Final Rejection	8	View
2022-08-26	`892`	List of references cited by examiner	1	View
2022-08-26	`SRFW`	Search information including classification, databases and other search related notes	2	View
2022-08-26	`SRNT`	Examiner's search strategy and results	1	View
2022-08-26	`SRNT`	Examiner's search strategy and results	7	View
2022-08-26	`FOR`	Foreign Reference	67	View
2022-08-08	`OATH`	Oath or Declaration filed	60	View
2022-06-24	`WFEE`	Fee Worksheet (SB06)	1	View
2022-06-24	`RCEX`	Request for Continued Examination (RCE)	3	View
2022-06-24	`AMSB`	Amendment Submitted/Entered with Filing of Continued Prosecution Application (CPA)/Request for Continued Examination(RCE)	1	View
2022-06-24	`CLM`	Claims	4	View
2022-06-24	`REM`	Applicant Arguments/Remarks Made in an Amendment	4	View
2022-06-24	`WFEE`	Fee Worksheet (SB06)	2	View
2022-06-24	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2022-03-24	`CTFR`	Final Rejection	6	View
2022-03-24	`SRFW`	Search information including classification, databases and other search related notes	1	View
2022-03-24	`SRNT`	Examiner's search strategy and results	6	View
2022-03-24	`1449`	List of References cited by applicant and considered by examiner	5	View
2022-03-24	`SRNT`	Examiner's search strategy and results	1	View
2022-01-13	`WFEE`	Fee Worksheet (SB06)	1	View
2022-01-13	`A...`	Amendment/Request for Reconsideration-After Non-Final Rejection	1	View
2022-01-13	`SPEC`	Specification	1	View
2022-01-13	`CLM`	Claims	4	View
2022-01-13	`REM`	Applicant Arguments/Remarks Made in an Amendment	5	View
2022-01-13	`WFEE`	Fee Worksheet (SB06)	2	View
2022-01-13	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2021-10-11	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	5	View
2021-10-11	`FOR`	Foreign Reference	16	View
2021-10-11	`FOR`	Foreign Reference	11	View
2021-10-11	`WFEE`	Fee Worksheet (SB06)	2	View
2021-10-11	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2021-10-11	`TRAN.LET`	Transmittal Letter	3	View
2021-09-13	`CTNF`	Non-Final Rejection	6	View
2021-09-13	`SRFW`	Search information including classification, databases and other search related notes	1	View
2021-09-13	`BIB`	Bibliographic Data Sheet	2	View
2021-09-13	`1449`	List of References cited by applicant and considered by examiner	4	View
2021-09-13	`1449`	List of References cited by applicant and considered by examiner	4	View
2021-09-13	`1449`	List of References cited by applicant and considered by examiner	4	View
2021-09-13	`1449`	List of References cited by applicant and considered by examiner	4	View
2021-09-13	`SRNT`	Examiner's search strategy and results	4	View
2021-09-13	`1449`	List of References cited by applicant and considered by examiner	37	View
2021-09-13	`SRNT`	Examiner's search strategy and results	1	View
2021-07-23	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2021-07-23	`ELC.`	Response to Election / Restriction Filed	1	View
2021-07-23	`REM`	Applicant Arguments/Remarks Made in an Amendment	1	View
2021-07-16	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2021-07-16	`FOR`	Foreign Reference	80	View
2021-07-16	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2021-07-16	`TRAN.LET`	Transmittal Letter	3	View
2021-06-28	`CTRS`	Requirement for Restriction/Election	6	View
2021-04-21	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2021-04-21	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2021-04-21	`TRAN.LET`	Transmittal Letter	3	View
2021-04-13	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2021-04-13	`N417`	Electronic Filing System Acknowledgment Receipt	3	View
2021-04-13	`TRAN.LET`	Transmittal Letter	3	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	9	View
2021-04-09	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	37	View
2021-04-09	`FOR`	Foreign Reference	96	View
2021-04-09	`FOR`	Foreign Reference	115	View
2021-04-09	`FOR`	Foreign Reference	51	View
2021-04-09	`FOR`	Foreign Reference	30	View
2021-04-09	`FOR`	Foreign Reference	68	View
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2021-04-09	`FOR`	Foreign Reference	34	View
2021-04-09	`FOR`	Foreign Reference	83	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	10	View
2021-04-09	`TRAN.LET`	Transmittal Letter	3	View
2021-04-09	`REF.OTHER`	Other reference-Patent/Application/Search Documents	3	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	10	View
2021-04-09	`REF.OTHER`	Other reference-Patent/Application/Search Documents	7	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	5	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	6	View
2021-04-09	`FOR`	Foreign Reference	97	View
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2021-04-09	`FOR`	Foreign Reference	129	View
2021-04-09	`N417`	Electronic Filing System Acknowledgment Receipt	4	View
2021-04-09	`FOR`	Foreign Reference	680	View
2020-08-20	`NTC.PUB`	Notice of Publication	1	View
2020-05-13	`M903`	Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed	2	View
2020-05-13	`APP.FILE.REC`	Filing Receipt	4	View
2020-05-13	`WFEE`	Fee Worksheet (SB06)	1	View
2020-04-06	`CRFE`	Sequence Listing in Computer Readable Format, No errors found	16	View
2020-04-03	`PEFR`	Applicant Response to Pre-Exam Formalities Notice	2	View
2020-04-03	`ABST`	Abstract	1	View
2020-04-03	`CLM`	Claims	6	View
2020-04-03	`SPEC`	Specification	80	View
2020-04-03	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2020-04-03	`SEQ.TXT`	Sequence Listing (Text File)	1	View
2020-02-04	`NT.CR.APP.PA`	Notice to File Corrected Application Papers	3	View
2020-02-04	`WCLM`	Claims Worksheet (PTO-2022)	1	View
2020-02-04	`SREXR.G`	Acceptance of Permission to Access Search Results	1	View
2020-02-04	`PD.AUTH.G`	Acceptance of Permission to Access Application	1	View
2020-02-04	`WFEE`	Fee Worksheet (SB06)	1	View
2019-11-05	`CRFD`	Sequence Listing in Computer Readable Format is Defective	19	View
2019-10-30	`SPEC`	Specification	80	View
2019-10-30	`DRW`	Drawings-only black and white line drawings	27	View
2019-10-30	`CLM`	Claims	6	View
2019-10-30	`ABST`	Abstract	2	View
2019-10-30	`FRPR`	Certified Copy of Foreign Priority Application	112	View
2019-10-30	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2019-10-30	`P.N.101.CONV`	PCT/RO/101 - Request form for new International Application - Conventional	5	View
2019-10-30	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2019-10-30	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2019-10-30	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2019-10-30	`IDS`	Information Disclosure Statement (IDS) Form (SB08)	4	View
2019-10-30	`FOR`	Foreign Reference	72	View
2019-10-30	`FOR`	Foreign Reference	75	View
2019-10-30	`PA..`	Power of Attorney	4	View
2019-10-30	`OATH`	Oath or Declaration filed	7	View
2019-10-30	`TRAN.LET`	Transmittal Letter	3	View
2019-10-30	`TRNA`	Transmittal of New Application	4	View
2019-10-30	`WFEE`	Fee Worksheet (SB06)	2	View
2019-10-30	`N417`	Electronic Filing System Acknowledgment Receipt	4	View
2019-10-30	`A.PE`	Preliminary Amendment	1	View
2019-10-30	`SPEC`	Specification	1	View
2019-10-30	`CLM`	Claims	7	View
2019-10-30	`REM`	Applicant Arguments/Remarks Made in an Amendment	1	View
2019-10-30	`ADS`	Application Data Sheet	10	View
2019-10-30	`DRW`	Drawings-only black and white line drawings	27	View
2019-10-30	`371P`	Documents submitted with 371 (National Stage) Applications	2	View
2019-10-30	`R3.73`	Assignee showing of ownership per 37 CFR 3.73	19	View
2019-10-30	`SEQ.TXT`	Sequence Listing (Text File)	1	View
2019-10-30	`371P`	Documents submitted with 371 (National Stage) Applications	7	View

Inventors

Soumendu Bhattacharya East Windsor, NJ

Chakravarthy Nachu Narasimhan Scotch Plains, NJ

Manoj K. Sharma Littleton, MA

Xiaoyu Yang Basking Ridge, NJ

Arnab De Burlington, MA

Rubi Burlage Florham Park, NJ

Jason K. Cheung Westfield, NJ

Attorneys & Agents of Record

ALYSIA FINNEGAN Reg. 48878 Attorney · MERCK

PATRICIA SHATYNSKI Reg. 43109 Attorney · MERCK & COMPANY, INC.

JOHN TODARO Reg. 36036 Attorney · MERCK

KEITH O'DOHERTY Reg. 80576 Attorney

SANJEEV MAHANTA Reg. 64174 Agent

KRISTI HARMAN Reg. 76825 Attorney · MERCK SHARP & DOHME LLC

SUSANNA BENN Reg. 63611 Agent · NIXON PEABODY LLP

STEVEN PAGEAU Reg. 80332 Attorney · MERCK

LI SU Reg. 45141 Attorney · MERCK

ANDREW CUSTER Reg. 56854 Attorney · MERCK

JULIE LAKE Reg. 51156 Attorney · MERCK

JEFFREY BERGMAN Reg. 51463 Agent · MERCK

EMILY SAUTER Reg. 67031 Attorney · KNOBBE MARTENS OLSON & BEAR

BAERBEL BROWN Reg. 47449 Attorney · MERCK

SARAH HOOSON Reg. 75870 Attorney

JANET FAIR Reg. 56042 Agent · MERCK

MARY MORRY Reg. 34398 Attorney · MERCK

SYLVIA AYLER Reg. 36436 Attorney · MERCK SHARP & DOHME

ZHIPENG ZHENG Reg. 80739 Attorney · COOLEY LLP

PATRICK REHFUSS Reg. 75367 Attorney · MERCK & CO., INC.

DANIEL WOODS Reg. 59864 Attorney · MERCK

J. FITZGERALD Reg. 71456 Agent · UNIVERSITY OF KANSAS MEDICAL CENTER

SAI VENKATESH SEETHARAMAN Reg. 72181 Attorney · MERCK

KAREN STOFFAN Reg. 54739 Attorney · MERCK

JOHN REILLY Reg. 43039 Attorney · MERCK

MATTHEW LEFF Reg. 50149 Attorney · MERCK

TAMARIA DEWDNEY Reg. 82437 Attorney · PROSKAUER ROSE LLP

NICOLE BEELER Reg. 45194 Attorney · MERCK

SU KYUNG SUH Reg. 73275 Agent · MERCK

DAVID KERWICK Reg. 56811 Attorney · MERCK

JAMES CORCORAN Reg. 70388 Agent · MERCK

CATHERINE FITCH Reg. 36502 Attorney · MERCK

LISA JAKOB Reg. 46181 Attorney · MERCK

ERIC GREENWALD Reg. 72159 Attorney · MERCK & CO., INC.

MINERVA WONG Reg. 77276 Agent · GOODWIN PROCTER, LLP

BENJAMIN ATKINS Reg. 77543 Attorney · MERCK SHARP & DOHME LLC

ANNA COCUZZO Reg. 42452 Attorney · MERCK

LAURA GINKEL Reg. 51737 Agent · MERCK

NICHOLE VALEYKO Reg. 55832 Attorney · MERCK & CO., INC.

DIANNE PECORARO Reg. 42068 Attorney · MERCK

ERIC MEADE Reg. 42876 Attorney · MERCK

Classification

USPC 424/143.1

A61P31/00 A61K39/39591 C07K16/2818 A61P35/00 A61K9/0019 A61K9/08 A61K9/19 A61K47/183 A61K47/20 A61K47/22 A61K47/26 A61K2039/505 A61K2039/507 C07K2317/565 C07K2317/94

Prosecution