IP Library Granted Patent US 7,807,445
Granted Patent B2
US 7,807,445 · App. 11/587,074 · Granted Oct 5, 2010

Antibiotic compound

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Quick Facts
Patent No.
US 7,807,445
App. No.
11/587,074
Granted
Oct 5, 2010
Kind
B2
Abstract

Fermentation of a nutrient medium with a eubacterium Streptomyces sp. yields a novel antibacterial compound of structural formula (I).

Claims (7)

1. An isolated compound of structural formula (I);

or a pharmaceutically acceptable salt thereof.

2. A process for the preparation of an isolated compound of structural formula (I):

which comprises the cultivation of a Streptomyce sp. with ATCC# PTA-5942 (MA7339) in a nutrient medium and isolating the Compound (I) from a fermentation broth.

3. The process of claim 2 wherein the fermentation is conducted at a temperature of about 10° C. to about 40° C.

4. The process of claim 3 , wherein the fermentation is conducted at a temperature of about 28° C.

5. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and an effective amount of a compound of structure (I) of claim 1 .

Assignments (6)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
CHANGE OF NAME Recorded Aug 29, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028866/0511 →
MERGER Recorded Aug 27, 2012
From: MERCK SHARP & DOHME CORP.
To: SCHERING CORPORATION
Reel/Frame 028850/0515 →
CHANGE OF NAME Recorded Jan 25, 2010
From: MERCK & CO., INC.
To: MERCK SHARP & DOHME CORP.
Reel/Frame 023837/0668 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 21, 2007
From: BASILIO, ANGELA; GENILLOUD, OLGA; GONZALEZ, IGNACIO; SALAZAR, OSCAR
To: MERCK SHARP AND DOHME DE ESPANA, S.A.
Reel/Frame 019462/0080 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 21, 2007
From: JAYASURIYA, HIRANTHI; SINGH, SHEO B.; WANG, JUN
To: MERCK & CO., INC.
Reel/Frame 019462/0199 →