Granted Patent
B2
US 9,833,448 · App. 15/293,569 · Granted Dec 5, 2017
Piperidinone carboxamide azaindane CGRP receptor antagonists
Inventors:
Ian M. Bell (Harleysville, PA); Mark E. Fraley (North Wales, PA); Steven N. Gallicchio (Horsham, PA); Anthony Ginnetti (Perkasie, PA); Helen J. Mitchell (Richboro, PA); Daniel V. Paone (Lansdale, PA); Donnette D. Staas (Harleysville, PA); Cheng Wang (Fort Washington, PA); C. Blair Zartman (Hatfield, PA)
Assignee:
Merck Sharp & Dohme Corp.
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Abstract
The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Claims (2)
1. A method of treating migraine in a mammalian patient in need of such treatment which method comprises administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising the compound of Formula II:
or a pharmaceutically acceptable salt thereof.
Assignments (2)
MERGER
Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jun 21, 2017
From: BELL, IAN M.; FRALEY, MARK E.; GALLICCHIO, STEVEN N.; GINNETTI, ANTHONY; MITCHELL, HELEN J.; PAONE, DANIEL V.; STAAS, DONNETTE D.; WANG, CHENG; ZARTMAN, C.BLAIR; STEVENSON, HEATHER E.
To: MERCK SHARP & DOHME CORP.
Reel/Frame 042765/0619 →
Continuity (5)
Provisional Application
61425034
· Dec 20, 2010
Provisional Application
61413077
· Nov 12, 2010