IP Library Granted Patent US 8,211,854
Granted Patent B2
US 8,211,854 · App. 12/688,664 · Granted Jul 3, 2012

Methods for inhibiting protein kinases

Assignee: Schering Corporation
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Quick Facts
Patent No.
US 8,211,854
App. No.
12/688,664
Granted
Jul 3, 2012
Kind
B2
Abstract

The present invention provides methods for inhibiting protein kinases selected from the group consisting of AKT, Checkpoint kinase, Aurora kinase, Pim kinases, and tyrosine kinase using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with protein kinases using such compounds.

Claims (4)

1. A method of inhibiting a Checkpoint kinase in a patient, comprising administering to the patient a therapeutically effective amount of a compound of formula:

or a pharmaceutically acceptable salt thereof.

2. A method of inhibiting a Checkpoint kinase in a patient, comprising administering to the patient a therapeutically effective amount of a compound of formula:

or a pharmaceutically acceptable salt thereof.

Assignments (2)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
CHANGE OF NAME Recorded Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →
Continuity (3)
Division 11542801 · Oct 4, 2006
Provisional Application 60724158 · Oct 6, 2005
Related Publication 20100125068A1 · May 20, 2010