IP Library › Granted Patent US 8,598,153
Granted Patent B2
US 8,598,153 · App. 13/435,130 · Granted Dec 3, 2013

Method of treatment using fatty acid synthesis inhibitors

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Quick Facts
Patent No.
US 8,598,153
App. No.
13/435,130
Granted
Dec 3, 2013
Kind
B2
Abstract

The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.

Claims (5)

1. A method of treating obesity comprising administration to a subject in need thereof a therapeutically effective amount of a compound of formula I or II

or a pharmaceutically acceptable salt thereof,

wherein represents a bond that can be absent or present.

2. The method according to claim 1 , wherein obesity is mediated by a melanocortin-4 receptor.

3. The method according to claim 2 wherein the subject is a mammal.

Assignments (1)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →