Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity

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Quick Facts

Patent No.: US 7,786,305
App. No.: 10/856,012
Granted: Aug 31, 2010
Kind: B2

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Abstract

The present invention is directed to compounds of the formula I: (wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. The present invention is also directed to intermediates useful in the preparation of formula I compounds.

Claims (10)

1. A compound selected from:

or a salt thereof.

2. The compound:

or a salt thereof.

3. The compound:

or a salt thereof.

4. The compound:

or a salt thereof.

5. The compound:

or salt thereof.

Assignments (5)