IP Library › Granted Patent US 8,476,425
Granted Patent B1
US 8,476,425 · App. 13/628,742 · Granted Jul 2, 2013

Tazobactam arginine compositions

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Quick Facts
Patent No.
US 8,476,425
App. No.
13/628,742
Granted
Jul 2, 2013
Kind
B1
Abstract

This disclosure provides compositions containing solid forms of tazobactam arginine, and methods of manufacturing and using these compositions.

Claims (3)

1. A composition comprising crystalline tazobactam arginine characterized by an X-ray powder diffraction pattern having peaks expressed in degrees 2-Theta±0.2° at angles of 4.8°, 8.9°, 11.3°, 14.9°, 18.0°, 19.4°, 21.3°, 22.8° and 24.3°.

2. The composition of claim 1 , further characterized by a differential scanning calorimetry thermogram having a characteristic peak expressed in units of ° C. at a temperature in the range of about 209.2 to about 211.9.

3. The composition of claim 1 , further characterized by a thermogravimetry curve with an onset temperature of about 201.9° C.

Assignments (6)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2015
From: CALIXA THERAPEUTICS, INC.
To: MERCK SHARP & DOHME CORP.
Reel/Frame 037198/0658 →
RELEASE OF SECURITY INTEREST Recorded Jul 24, 2015
From: ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT
To: CALIXA THERAPEUTICS, INC.; ADOLOR CORPORATION; CUBIST PHARMACEUTICALS, INC.
Reel/Frame 036180/0070 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 25, 2013
From: CUBIST PHARMACEUTICALS, INC.
To: CALIXA THERAPEUTICS, INC.
Reel/Frame 030876/0432 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 8, 2013
From: LAI, JAN-JI; GU, JIAN-QIAO; PATHARE, PRADIQ M.; JURKAUSKAS, VALDAS; TERRACCIANO, JOSEPH; DAMOUR, NICOLE MILLER
To: CUBIST PHARMACEUTICALS, INC.
Reel/Frame 029778/0208 →
SECURITY AGREEMENT Recorded Nov 20, 2012
From: CUBIST PHARMACEUTICALS, INC.; ADOLOR CORPORATION; CALIXA THERAPEUTICS, INC.; CUBIST PHARMACEUTICALS HOLDINGS, INC.; CUBIST PHARMACEUTICALS U.S.
To: ROYAL BANK OF CANADA, AS ADMINISTRATIVE AGENT
Reel/Frame 029339/0669 →