IP Library › Granted Patent US 9,499,541
Granted Patent B2
US 9,499,541 · App. 14/505,255 · Granted Nov 22, 2016

Piperidinone carboxamide indane CGRP receptor antagonists

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Quick Facts
Patent No.
US 9,499,541
App. No.
14/505,255
Granted
Nov 22, 2016
Kind
B2
Abstract

The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

Claims (4)

1. A compound which is:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition which comprises an inert carrier and a compound of claim 1 , or a pharmaceutically acceptable salt thereof.

3. A method of treating headache in a mammalian patient in need of such treatment, which comprises administering to the patient a therapeutically effective amount of a compound of claim 1 or a pharmaceutically acceptable salt thereof.

Assignments (1)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →