Compounds that are ERK inhibitors
View Patent ↗Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
1. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
2. The compound of claim 1 wherein said compound is:
3. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
4. The compound of claim 3 wherein said compound is:
5. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
6. The compound of claim 5 wherein said compound is:
7. A pharmaceutical composition comprising the compound of claim 1 .
8. A pharmaceutical composition comprising the compound of claim 3 .
9. A pharmaceutical composition comprising the compound of claim 5 .
10. A compound of the formula:
or a pharmaceutically acceptable salt thereof.
11. The compound of claim 10 wherein the compound is:
12. A pharmaceutical composition comprising the compound of claim 10 .