IP Library Granted Patent US 8,673,900
Granted Patent B2
US 8,673,900 · App. 13/128,493 · Granted Mar 18, 2014

Gamma secretase modulators

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Quick Facts
Patent No.
US 8,673,900
App. No.
13/128,493
Granted
Mar 18, 2014
Kind
B2
Abstract

In many embodiments, the present invention provides novel heterocyclic compounds which are modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compositions.

Claims (3)

1. A compound selected from the group consisting of compounds of,

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a therapeutically effective amount of a compound of claim 1 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.

Assignments (4)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
CHANGE OF NAME Recorded Apr 1, 2013
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 030124/0667 →
CHANGE OF NAME Recorded Aug 30, 2012
From: SCHERING CORPORATION
To: MERCK SHARP & DOHME CORP.
Reel/Frame 028884/0151 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2011
From: ZHU, ZHAONING; GREENLEE, WILLIAM J.; HUANG, XIANHAI; QIN, JUN; LIU, XIAOXIANG; LI, HONGMEI; ZHOU, WEI; PALANI, ANANDAN; ZHU, XIAOHONG; VICAREL, MONICA L.; MANDAL, MIHIRBARAN; SUN, ZHONG-YUE; BENNETT, CHAD E.; MCCRACKEN, TROY MICHAEL; GALLO, GIOCONDA
To: SCHERING CORPORATION
Reel/Frame 026834/0415 →