IP Library Granted Patent US 9,403,790
Granted Patent B2
US 9,403,790 · App. 15/006,220 · Granted Aug 2, 2016

Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes

Inventors: Tesfaye Biftu (Freehold, NJ); Ann E. Weber (Scotch Plains, NJ); Ping Chen (Edison, NJ)
Assignee: Merck Sharp & Dohme Corp.
C07D309/30
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Quick Facts
Patent No.
US 9,403,790
App. No.
15/006,220
Granted
Aug 2, 2016
Kind
B2
Abstract

The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

Claims (1)

1. A compound having the following structure:

Assignments (1)
MERGER Recorded Aug 8, 2022
From: MERCK SHARP & DOHME CORP.
To: MERCK SHARP & DOHME LLC
Reel/Frame 061102/0145 →
Continuity (9)
Continuation 14825535 · Aug 13, 2015
Continuation 14591124 · Jan 7, 2015
Continuation 14293031 · Jun 2, 2014
Continuation 14059638 · Oct 22, 2013
Continuation 13761407 · Feb 7, 2013
Continuation 13398887 · Feb 17, 2012
Continuation 12616831 · Nov 12, 2009
Provisional Application 61199179 · Nov 13, 2008
Related Publication 20160137622A1 · May 19, 2016