IP Library › Granted Patent US 7,368,284
Granted Patent B2
US 7,368,284 · App. 10/863,116 · Granted May 6, 2008

Porcine CMP-N-Acetylneuraminic acid hydroxylase gene

Assignee: University of Pittsburgh
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Quick Facts
Patent No.
US 7,368,284
App. No.
10/863,116
Granted
May 6, 2008
Kind
B2
Abstract

The present invention provides porcine CMP-N-Acetylneuraminic-Acid Hydroxylase (CMP-Neu5Ac hydroxylase) protein, cDNA, and genomic DNA regulatory sequences. Furthermore, the present invention includes porcine animals, tissues, and organs, as well as cells and cell lines derived from such animals, tissues, and organs, which lack expression of functional CMP-Neu5Ac hydroxylase. Such animals, tissues, organs, and cells can be used in research and in medical therapy, including in xenotransplantation, and in industrial livestock farming operations.

Claims (4)

1. An isolated nucleotide comprising a nucleotide sequence of SEQ ID No 46.

2. A vector comprising a sequence of claim 1 .

3. A nucleic acid construct comprising a sequence of claim 1 .

4. A plasmid comprising a sequence of claim 1 .

Assignments (3)
CONFIRMATORY LICENSE Recorded Sep 24, 2019
From: UNIVERSITY OF PITTSBURGH
To: NATIONAL INSTITUTES OF HEALTH (DEITR)
Reel/Frame 050478/0871 →
CONFIRMATORY LICENSE Recorded Sep 11, 2008
From: UNIVERSITY OF PITTSBURGH
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021516/0438 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2004
From: KOIKE, CHIHIRO
To: UNIVERSITY OF PITTSBURGH
Reel/Frame 015447/0978 →
Continuity (2)
Provisional Application 6047639600 · Jun 6, 2003
Related Publication 20050223418A1 · Oct 6, 2005